[en] Three undescribed oleanolic acid glycosides, together with four known ones, were isolated from root barks of two species of Olax: 3-O-α-L-rhamnopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→3)-β-D-glucuronopyranosyloleanolic acid and 3-O-α-L-rhamnopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→3)-β-D-glucuronopyranosyloleanolic acid 28-O-β-D-glucopyranosyl ester from Olax wildemanii, and 3-O-β-D-glucopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→3)]-β-D-glucuronopyranosyloleanolic acid from Olax subscorpioidea. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR experiments in combination with mass spectrometry. These molecules showed no antimicrobial activity against Candida albicans, Staphylococcus aureus and Pseudomonas aeruginosa.
Pertuit, David; Centre des Sciences du Goût et de l′Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Dijon, France
Sautour, Marc ; Parasitology and Mycology Laboratory, Hôpital du Bocage, Dijon cedex, France
Miyamoto, Tomofumi; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
Delaude, Clément ; Université de Liège - ULiège > Département de chimie (sciences) > Centre de recherche phytochimique
Kapundu, Mpuza; Centre d′études des Substances Naturelles d′Origine Végétale, Faculté des Sciences Pharmaceutiques, Université de Kinshasa, Democratic Republic Congo
Lacaille-Dubois, Marie-Aleth; Centre des Sciences du Goût et de l′Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Dijon, France
Mitaine-Offer, Anne-Claire; Centre des Sciences du Goût et de l′Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Dijon, France
Language :
English
Title :
Oleanolic acid glycosides from two species of Olax: Olax wildemanii and Olax subscorpioidea
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