[en] Short- and medium-chain chlorinated paraffins (SCCPs and MCCPs) are hazardous industrial chemicals that tend to bioaccumulate in animal-derived foodstuffs through the food supply chain. However, the lack of reliable noninvasive bioindicators hinders the monitoring of farm animal exposure to CPs. In this study, 169 cattle hair samples were collected from beef cattle farms in six Chinese provinces, with further beef, feed, and soil samples being collected in Hebei province. Geographical differences in CP concentrations were observed in the hair samples, and CP concentrations in samples collected from Hebei province decreased in the following order: hair > feed > beef > soil. C10-11Cl6-7 and C14Cl7-8 were the predominant SCCPs and MCCPs, respectively, in all the hair, beef, feed, and soil samples. CP concentrations in hair samples significantly correlated with those in beef, feed, and soil samples, indicating that hair can be used as a bioindicator of cattle exposure to CPs. The possible health risks associated with exposure to CPs through beef consumption, especially for children and high-volume beef consumers, should be further investigated.
Disciplines :
Chemistry
Author, co-author :
Dong, Shujun; Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China
Zhang, Su; Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China
Suo, Decheng; Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China
Wu, Xingyi; Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China, College of Science, China Agricultural University, Beijing 100193, China
Han, Xiaoxu; National Center of Technology Innovation for Dairy, Huhehaote 010100, China
Liang, Meng; Shandong Provincial Key Laboratory of Quality Safety Monitoring and Risk Assessment for Animal Products, Shandong Center for Quality Control of Feed and Veterinary Drug, Jinan 250100, China
Cao, Jun; Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China
Zou, Yun ; Organic Biological Analytical Chemistry Group, Department of Chemistry, University of Liège, Liège 4000, Belgium
Pei, Xiaoyan; National Center of Technology Innovation for Dairy, Huhehaote 010100, China
Wang, Peilong; Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: wangpeilong@caas.cn
Language :
English
Title :
Cattle hair as a bioindicator for short- and medium-chain chlorinated paraffin monitoring on cattle farms.
This study was supported by the National Center of Technology Innovation for Dairy (grant no. 2022-KYGG-13), and Agricultural Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences (grant no. CAAS-ASTIP-IQSTAP-04).
Aamir, M., Yin, S., Zhou, Y., Xu, C., Liu, K., Liu, W., Congener-specific C10-C13 and C14-C17 chlorinated paraffins in Chinese agricultural soils: Spatio-vertical distribution, homologue pattern and environmental behavior. Environ Pollut 245 (2019), 789–798, 10.1016/j.envpol.2018.10.132.
Brits, M., de Boer, J., Rohwer, E.R., De Vos, J., Weiss, J.M., Brandsma, S.H., Short-, medium-, and long-chain chlorinated paraffins in South African indoor dust and cat hair. Chemosphere, 238, 2020, 124643, 10.1016/j.chemosphere.2019.124643.
Chen, S., Gong, Y., Luo, Y., Cao, R., Yang, J., Cheng, L., Gao, Y., Zhang, H., Chen, J., Geng, N., Toxic effects and toxicological mechanisms of chlorinated paraffins: A review for insight into species sensitivity and toxicity difference. Environ Inter, 178, 2023, 108020, 10.1016/j.envint.2023.108020.
Chinese Nutrition Society, 2022. Chinese Dietary Guidelines 2022. People's Medical Publishing House. Beijing, China. (in Chinese).
Cui, L., Gao, L., Zheng, M., Li, J., Zhang, L., Wu, Y., Qiao, L., Xu, C., Wang, K., Huang, D., Short- and medium-chain chlorinated paraffins in foods from the sixth Chinese Total Diet Study: Occurrences and estimates of dietary intakes in South China. J Agric Food Chem 68 (2020), 9043–9051, 10.1021/acs.jafc.0c03491.
Dong, S., Zhang, S., Li, X., Wei, S., Li, T., Zou, Y., Zhang, W., Cheng, J., Wang, R., Wang, P., Su, X., Occurrence of short- and medium-chain chlorinated paraffins in raw dairy cow milk from five Chinese provinces. Environ Inter, 136, 2020, 105466, 10.1016/j.envint.2020.105466.
Dong, S., Zhang, S., Wu, X., Cao, J., Yan, M., Zou, Y., Yan, H., Tang, J., Suo, D., Wang, P., A preliminary study on short- and medium-chain chlorinated paraffins in duck farms: Concentrations, distribution, and dietary exposure risks. Environ Res, 246, 2024, 118109, 10.1016/j.envres.2024.118109.
Dong, S., Zhang, S., Zou, Y., Fan, M., Wang, Y., Cheng, J., Wang, R., Li, T., Li, X., Wang, P., Concentrations and sources of short- and medium-chain chlorinated paraffins in farmed Chinese mitten crabs in China. J Hazard Mater, 411, 2021, 125076, 10.1016/j.jhazmat.2021.125076.
Esteban, M., Castano, A., Non-invasive matrices in human biomonitoring: A review. Environ Inter 35:2 (2009), 438–449, 10.1016/j.envint.2008.09.003.
Glüge, J., Wang, J., Bogdal, Z., Scheringer, C., Hungerbühler, M., K, Global production, use, and emission volumes of short-chain chlorinated paraffins - A minimum scenario. Sci Total Environ 573 (2016), 1132–1146, 10.1016/j.scitotenv.2016.08.105.
Han, X., Chen, H., Shen, M., Deng, M., Du, B., Zeng, L., Hair and nails as noninvasive bioindicators of human exposure to chlorinated paraffins: Contamination patterns and potential influencing factors. Sci Total Environ, 798, 2021, 149257, 10.1016/j.scitotenv.2021.149257.
Huang, H., Gao, L., Zheng, M., Li, J., Zhang, L., Wu, Y., Wang, R., Xia, D., Qiao, L., Cui, L., Dietary exposure to short- and medium-chain chlorinated paraffins in meat and meat products from 20 provinces of China. Environ Pollut 233 (2018), 439–445, 10.1016/j.envpol.2017.10.022.
Iino, F., Takasuga, T., Senthilkumar, K., Nakamura, N., Nakanishi, J., Risk assessment of short-chain chlorinated paraffins in Japan based on the first Market Basket Study and species sensitivity distributions. Environ Sci Technol 39:3 (2005), 859–866, 10.1021/es049221.
Kräetschmer, K., Schäechtele, A., Vetter, W., Short- and medium-chain chlorinated paraffin exposure in South Germany: A total diet, meal and market basket study. Environ Pollut, 272, 2021, 116019, 10.1016/j.envpol.2020.116019.
Lee, S., Choo, G., Ekpe, O.D., Kim, J., Oh, J.E., Short-chain chlorinated paraffins in various foods from Republic of Korea: Levels, congener patterns, and human dietary exposure. Environ Pollut, 263, 2020, 114520, 10.1016/j.envpol.2020.114520.
Lin, Y., Feng, C., Le, S., Qiu, X., Xu, Q., Jin, S., Fang, Y., Jin, Y. e, Wen, Y., Wang, G., Lu, D., Infant exposure to PCBs and PBDEs revealed by hair and human milk analysis: Evaluation of hair as an alternative biomatrix. Environ Sci Technol 56:22 (2022), 15912–15919, 10.1021/acs.est.2c04045.
McGrath, T.J., Limonier, F., Poma, G., Bombeke, J., Winand, R., Vanneste, K., Andjelkovic, M., Van Hoeck, E., Joly, L., Covaci, A., Concentrations and distribution of chlorinated paraffins in Belgian foods. Environ Pollut, 291, 2021, 118263, 10.1016/j.envpol.2021.118236.
Poon, S., Wade, M.G., Aleksa, K., Rawn, D.F.K., Carnevale, A., Gaertner, D.W., Sadler, A., Breton, F., Koren, G., Ernest, S.R., Lalancette, C., Robaire, B., Hales, B.F., Goodyer, C.G., Hair as a biomarker of systemic exposure to polybrominated diphenyl ethers. Environ Sci Technol 48:24 (2014), 14650–14658, 10.1021/es502789h.
Reth, M., Zencak, Z., Oehme, M., First study of congener group patterns and concentrations of short- and medium-chain chlorinated paraffins in fish from the North and Baltic Sea. Chemosphere 58 (2005), 847–854, 10.1016/j.chemosphere.2004.09.036.
Schrenk, D., Bignami, M., Bodin, L., Chipman, J.K., del Mazo, J., Grasl-Kraupp, B., Hogstrand, C., Hoogenboom, L.R., Leblanc, J.-C., Nebbia, C.S., Ntzani, E., Petersen, A., Sand, S., Schwerdtle, T., Vleminckx, C., Wallace, H., Brschweiler, B., Leonards, P., Rose, M., Binaglia, M., Horvth, Z., Bordajandi, L.R., Nielsen, E., Chain, E.P.C.F., Risk assessment of chlorinated paraffins in feed and food. EFSA J, 18, 2020, 5991, 10.2903/j.efsa.2020.5991.
Taylor, S., Lynch, M., Terkildsen, M., Stevenson, G., Yates, A., Piro, N., de Araujo, J., Gray, R., Utility of fur as a biomarker for persistent organic pollutants in Australian fur seals (Arctocephalus pusillus doriferus). Sci Total Environ 610, 2018, 1310–1320, 10.1016/j.scitotenv.2017.08.204.
UNEP, 2017, The 16 New POPs. An introduction to the chemicals added to the Stockholm Convention as Persistent Organic Pollutants by the Conference of the Parties. http://chm.pops.int/TheConvention/ThePOPs/TheNewPOPs/tabid/2511/Default.aspx.
United Nations Environment Program (UNEP), 2022. Report of the Persistent Organic Pollutants Review Committee on the work of its eighteenth meeting. UNEP/POPS/POPRC.18/11/Add.3. https://chm.pops.int/Convention/POPsReviewCommittee/Chemicals/tabid/243/Default.aspx.
Zheng, J., Chen, K.-H., Luo, X.-J., Yan, X., He, C.-T., Yu, Y.-J., Hu, G.-C., Peng, X.-W., Ren, M.-Z., Yang, Z.-Y., Mai, B.-X., Polybrominated diphenyl Ethers (PBDEs) in paired human hair and serum from e-waste recycling workers: Source apportionment of hair PBDEs and relationship between hair and serum. Environ Sci Technol 48:1 (2014), 791–796, 10.1021/es4044402.
Zhou, W., Huang, K., Bu, D., Zhang, Q., Fu, J., Hu, B., Zhou, Y., Chen, W., Fu, Y., Zhang, A., Fu, J., Jiang, G., Remarkable contamination of short- and medium- chain chlorinated paraffins in free-range chicken eggs from rural Tibetan Plateau. Environ Sci Technol 58:11 (2024), 5093–5102, 10.1021/acs.est.3c08815.
