[en] OBJECTIVE: To assess in vivo blood oxygen binding in double-muscled calves and dairy calves with conventional muscle conformation. ANIMALS: 58 dairy and 48 double-muscled calves. PROCEDURE: Calves were classified as neonatal (24 hours old) or older calves (2 to 26 days old). Venous and arterial blood samples were collected, and hemoglobin concentration, pH, PCO2, and PO2 were determined. Blood oxygen equilibrium curves (OEC) under standard conditions were constructed, and the oxygen exchange fraction (OEF) and the amount of oxygen released at the tissue level by 100 ml of blood (OEF Vol%) were calculated. RESULTS: In each breed, partial pressure of oxygen at 50% saturation of hemoglobin (P50) under standard conditions was significantly higher in older than in neonatal calves, indicating a right shift in OEC with age. Venous P50 was significantly lower in neonatal double-muscled calves than in neonatal dairy calves, but arterial and venous P50 were significantly higher in older double-muscled calves than in older dairy calves. In double-muscled, but not in dairy, calves, OEF was significantly higher in older than in neonatal calves. In neonatal calves, OEF Vol% was not significantly different between breeds, but OEF Vol% was significantly higher in older double-muscled calves than in older dairy calves. CONCLUSIONS AND CLINICAL RELEVANCE: The lower OEF in neonatal double-muscled calves, compared with dairy calves, could contribute to the higher sensitivity of double-muscled calves to hypoxia. Blood oxygen affinity decreased with age, but OEF and OEF Vol% were unchanged with age in dairy calves, whereas they increased with age in double-muscled calves
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Cambier, Carole ; Université de Liège - ULiège > Département de sciences fonctionnelles > Département de sciences fonctionnelles
Clerbaux, T.; Cliniques Universitaires Saint-Luc (Bruxelles) > Division of Pneumology
Detry, B.; Cliniques Universitaires Saint-Luc (Bruxelles) > Division of Pneumology
Beerens, Dominique ; Université de Liège - ULiège > Département de sciences fonctionnelles > Département de sciences fonctionnelles
Frans, A.; Cliniques Universitaires Saint-Luc (Bruxelles) > Division of Pneumology
Gustin, Pascal ; Université de Liège - ULiège > Département de sciences fonctionnelles > Pharmacologie, pharmacothérapie et toxicologie
Language :
English
Title :
Blood Oxygen Binding in Double-Muscled Calves and Dairy Calves with Conventional Muscle Conformation
Publication date :
2000
Journal title :
American Journal of Veterinary Research
ISSN :
0002-9645
eISSN :
1943-5681
Publisher :
American Veterinary Medical Association
Volume :
61
Issue :
3
Pages :
299-304
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
Walloon Region (DGTRE grants number 3012 and 2555)
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