[en] Understanding the factors that predict why some individuals perceive to respond more to meditation training than others could impact the development, efficacy, adherence levels, and implementation of meditation-based interventions. We investigated individual-level variables associated with self- and teacher-perceived responsiveness to longer-term meditation training. This study presents a secondary analysis of the Age-Well trial (NCT02977819, 30/11/2016) and includes 90 healthy older adults (65-84 years) that were randomised to an 18-month meditation training or a non-native language (English) training. Responsiveness was measured post-intervention using participants' and teachers' ratings of four psychological domains (connection, positive/negative emotions, meta-awareness) in relation to two contexts (during sessions, in daily life), teachers' perception of overall benefit, and a global composite comprising all self- and teacher-perceived responsiveness measures. Linear regression modelling indicates that, when including baseline variables (sex, education, neuroticism, cognition, expectancy) and engagement (hours of formal practice during intervention), only higher levels of engagement were associated with higher global composite scores (standardised estimate = 0.50, 95% CI: 0.24-0.77, p < 0.001). Global composite scores were not correlated with pre-post changes in well-being. Findings indicate that more time spent practising meditation was related to greater perceived intervention effects. We suggest that future studies closely monitor levels of engagement and map reasons for disengagement.
Research Center/Unit :
GIGA CRC In vivo Imaging - ULiège
Disciplines :
Neurosciences & behavior
Author, co-author :
Schlosser, Marco; Division of Psychiatry, Faculty of Brain Sciences, University College London, London, UK. marco.schlosser@ucl.ac.uk ; Institut für Psychotherapie Potsdam, Potsdam, Germany. marco.schlosser@ucl.ac.uk
Gonneaud, Julie; Normandie Univ, UNICAEN, INSERM, U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Institut Blood and Brain @ Caen-Normandie, Cyceron, Caen, France
Poletti, Stefano; Eduwell team, Lyon Neuroscience Research Center, Inserm U1028, CNRS UMR5292, Lyon 1 University, Lyon, France
Bouet, Romain; Eduwell team, Lyon Neuroscience Research Center, Inserm U1028, CNRS UMR5292, Lyon 1 University, Lyon, France
Klimecki, Olga M; Institute of Psychology, Department of Developmental Psychology, Friedrich-Schiller- Universität Jena, Jena, Germany ; Biological Psychology, Faculty of Psychology, Technische Universität Dresden, Dresden, Germany
Collette, Fabienne ; Université de Liège - ULiège > Département de Psychologie ; Université de Liège - ULiège > GIGA > GIGA CRC In vivo Imaging - Aging & Memory ; Université de Liège - ULiège > Psychologie et Neuroscience Cognitives (PsyNCog) > Cognition et Langage
Marchant, Natalie L; Division of Psychiatry, Faculty of Brain Sciences, University College London, London, UK
Chételat, Gaël; Normandie Univ, UNICAEN, INSERM, U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Institut Blood and Brain @ Caen-Normandie, Cyceron, Caen, France
Lutz, Antoine; Eduwell team, Lyon Neuroscience Research Center, Inserm U1028, CNRS UMR5292, Lyon 1 University, Lyon, France. antoine.lutz@inserm.fr
Medit-Ageing Research Group
Language :
English
Title :
Meditation dosage predicts self- and teacher-perceived responsiveness to an 18-month randomised controlled trial.
H2020 - 667696 - MEDIT-AGEING - Investigating the impact of meditation training on mental health and wellbeing in the ageing population
Funders :
European Union
Funding text :
The Medit-Ageing Research Group includes: Claire Andr\u00E9, Florence Allais, Julien Asselineau, Eider Arenaza-Urquijo, Sebastian Baez, Martine Batchelor, Axel Beaugonin, Maelle Botton, Pierre Champetier, Anne Chocat, Nina Coll, Sophie Dautricourt, Pascal Delamillieure, Vincent De La Sayette, Marion Delarue, Harriet Demnitz-King, Titi Dolma, St\u00E9phanie Egret, Francesca Felisatti, Eglantine Ferrand-Devouges, Eric Frison, Francis Gheysen, Agathe Joret Philippe, Elizabeth Kuhn, Brigitte Landeau, Gwendoline Ledu, Val\u00E9rie Lefranc, Maria Leon, Florence Mezenge, In\u00E8s Moulinet, Theresa Mueller, Valentin Ourry, Cassandre Palix, L\u00E9o Paly, G\u00E9raldine Poisnel, Anne Quillard, G\u00E9raldine Rauchs, Florence Requier, Eric Salmon, Corrine Schwimmer, Edelweiss Touron, Denis Vivien, Patrik Vuilleumier, C\u00E9drick Wallet, Caitlin Ware, and Tim Whitfield. The authors would like to thank all the contributors listed in the Medit-Ageing Research Group as well as Rhonda Smith, Charlotte Reid, the sponsor (P\u00F4le de Recherche Clinique at Inserm), Inserm Transfert (Delphine Smagghe), the teachers, and the participants in the Medit-Ageing project. Fabienne Collette is Research Director at the Belgian National Fund for Scientific Research (F.R.S.-FNRS).GC, FC, OMK, AL, and NLM have received research support from the EU\u2019s Horizon 2020 research and innovation programme (grant agreement number 667696). GC has received research support from Inserm, Fondation d\u2019entreprise MMA des Entrepreneurs du Futur, Fondation Alzheimer, Programme Hospitalier de Recherche Clinique, R\u00E9gion Normandie, Association France Alzheimer et maladies apparent\u00E9es and Fondation Vaincre Alzheimer (all to Inserm), GC and AL have received research support and personal fees from Fondation d\u2019entreprise MMA des Entrepreneurs du Futur. All other authors have declared that no competing interests exist.
C.J. Dahl A. Lutz R.J. Davidson Reconstructing and deconstructing the self: cognitive mechanisms in meditation practice Trends Cogn. Sci. 2015 19 515 523 10.1016/j.tics.2015.07.001 26231761 4595910
C.J. Dahl C.D. Wilson-Mendenhall R.J. Davidson The plasticity of well-being: a training-based framework for the cultivation of human flourishing Proc. Natl. Acad. Sci. 2020 117 32197 32206 2020PNAS.11732197D 10.1073/pnas.2014859117 33288719 7768706
R.E. Laukkonen H.A. Slagter From many to (n)one: meditation and the plasticity of the predictive mind Neurosci. Biobehav Rev. 2021 128 199 217 10.1016/j.neubiorev.2021.06.021 34139248
A. Lutz A.P. Jha J.D. Dunne C.D. Saron Investigating the phenomenological matrix of mindfulness-related practices from a neurocognitive perspective Am. Psychol. 2015 70 632 658 10.1037/a0039585 26436313 4608430
M.J. Wright J.L. Sanguinetti S. Young M.D. Sacchet Uniting contemplative theory and Scientific Investigation: toward a Comprehensive Model of the mind Mindfulness 2023 14 1088 1101 10.1007/s12671-023-02101-y
Burbea, R. Seeing that Frees: Meditations on Emptiness and Dependent Arising (Hermes Amara, 2014). https://troubador.co.uk/bookshop/mind-body-spirit/seeing-that-frees
Gallagher, S. et al. The self-pattern and Buddhist Psychology. Mindfulness 2023. https://doi.org/10.1007/s12671-023-02118-3
A. Lutz H.A. Slagter J.D. Dunne R.J. Davidson Attention regulation and monitoring in meditation Trends Cogn. Sci. 2008 12 163 169 10.1016/j.tics.2008.01.005 18329323 2693206
N.T. Van Dam et al. Mind the hype: a critical evaluation and prescriptive agenda for Research on Mindfulness and Meditation Perspect. Psychol. Sci. 2018 13 36 61 10.1177/1745691617709589 29016274
J. Galante et al. A Framework for the empirical investigation of Mindfulness Meditative Development Mindfulness 2023 14 1054 1067 10.1007/s12671-023-02113-8
K.C.R. Fox et al. Functional neuroanatomy of meditation: a review and meta-analysis of 78 functional neuroimaging investigations Neurosci. Biobehav Rev. 2016 65 208 228 10.1016/j.neubiorev.2016.03.021 27032724
M. Goyal et al. Meditation Programs for Psychological Stress and Well-being: a systematic review and Meta-analysis JAMA Intern. Med. 2014 174 357 368 10.1001/jamainternmed.2013.13018 24395196 4142584
B. Khoury B. Knäuper M. Schlosser K. Carrière A. Chiesa Effectiveness of traditional meditation retreats: a systematic review and meta-analysis J. Psychosom. Res. 2017 92 16 25 10.1016/j.jpsychores.2016.11.006 27998508
P. Sedlmeier et al. The psychological effects of meditation: a meta-analysis Psychol. Bull. 2012 138 1139 1171 10.1037/a0028168 22582738
T. Whitfield et al. The Effect of Mindfulness-based programs on cognitive function in adults: a systematic review and Meta-analysis Neuropsychol. Rev. 2022 32 677 702 10.1007/s11065-021-09519-y 34350544
J. Wielgosz S.B. Goldberg T.R.A. Kral J.D. Dunne R.J. Davidson Mindfulness Meditation and Psychopathology Annu. Rev. Clin. Psychol. 2019 15 285 316 10.1146/annurev-clinpsy-021815-093423 30525995
R.J. Davidson A.W. Kaszniak Conceptual and methodological issues in Research on Mindfulness and Meditation Am. Psychol. 2015 70 581 592 10.1037/a0039512 26436310 4627495
S.B. Goldberg K.M. Riordan S. Sun R.J. Davidson The empirical status of mindfulness-based interventions: a systematic review of 44 Meta-analyses of Randomized controlled trials Perspect. Psychol. Sci. 2022 17 108 130 10.1177/1745691620968771 33593124
B. Khoury et al. Mindfulness-based therapy: a comprehensive meta-analysis Clin. Psychol. Rev. 2013 33 763 771 10.1016/j.cpr.2013.05.005 23796855
I. Buric M. Farias J.M.A. Driessen I.A. Brazil Individual differences in meditation interventions: a meta-analytic study Br. J. Health Psychol. 2022 27 1043 1076 10.1111/bjhp.12589 35224829 9543193
Sieder, K., Thiedmann, P., Voracek, M. & Tran, U. S. Baseline trait mindfulness moderates the efficacy of mindfulness interventions and active controls: a meta-analysis of 177 randomised controlled trials. Appl. Psychol. Health Well-Being 2024,1–24. https://doi.org/10.1111/aphw.12550
S.B. Goldberg A common factors perspective on mindfulness-based interventions Nat. Rev. Psychol. 2022 1 605 619 10.1038/s44159-022-00090-8 36339348 9635456
H. Demnitz-King et al. Effects of Meditation Training and Non-native Language Training on Cognition in older adults: a secondary analysis of a Randomized Clinical Trial JAMA Netw. Open. 2023 6 e2317848 10.1001/jamanetworkopen.2023.17848 37450303 10349342
M. Schlosser et al. An 18-month meditation training selectively improves psychological well-being in older adults: a secondary analysis of a randomised controlled trial PLOS ONE 2023 18 e0294753 10.1371/journal.pone.0294753 38039341 10691714
M. Schlosser et al. Effects of a mindfulness-based intervention and a health self-management programme on psychological well-being in older adults with subjective cognitive decline: secondary analyses from the SCD-Well randomised clinical trial PLOS ONE 2023 18 e0295175 10.1371/journal.pone.0295175 38100477 10723715
T. Whitfield et al. Effects of a mindfulness-based versus a health self-management intervention on objective cognitive performance in older adults with subjective cognitive decline (SCD): a secondary analysis of the SCD-Well randomized controlled trial Alzheimers Res. Ther. 2022 14 125 10.1186/s13195-022-01057-w 36068621 9446839
H.C.W. de Vet et al. Minimally important change values of a measurement instrument depend more on baseline values than on the type of intervention J. Clin. Epidemiol. 2015 68 518 524 10.1016/j.jclinepi.2014.07.008 25544741
P. Grossman On the porosity of subject and object in ‘mindfulness’ scientific study: challenges to ‘scientific’ construction, operationalization and measurement of mindfulness Curr. Opin. Psychol. 2019 28 102 107 10.1016/j.copsyc.2018.11.008 30583202
Y. Kang et al. Gender differences in response to a school-based mindfulness training intervention for early adolescents J. Sch. Psychol. 2018 68 163 176 10.1016/j.jsp.2018.03.004 29861026 6174072
Rojiani, R., Santoyo, J. F., Rahrig, H., Roth, H. D. & Britton, W. B. Women Benefit More Than Men in Response to College-based Meditation Training. Front. Psychol. 8, 551. https://doi.org/10.3389/fpsyg.2017.00551 (2017).
D. Katz B. Toner A systematic review of gender differences in the effectiveness of mindfulness-based treatments for Substance Use disorders Mindfulness 2013 4 318 331 10.1007/s12671-012-0132-3
I. Nyklíček M. Irrmischer For whom does Mindfulness-based stress reduction work? Moderating effects of personality Mindfulness 2017 8 1106 1116 10.1007/s12671-017-0687-0 28757903 5506177
M.A. Rosenkranz J.D. Dunne R.J. Davidson The next generation of mindfulness-based intervention research: what have we learned and where are we headed? Curr. Opin. Psychol. 2019 28 179 183 10.1016/j.copsyc.2018.12.022 30739006 6609495
S. Strohmaier The relationship between doses of mindfulness-based programs and depression, anxiety, stress, and Mindfulness Randomized Controlled Trials Mindfulness 2020 11 1315 1335 10.1007/s12671-020-01319-4
G. Chételat et al. Effect of an 18-Month Meditation Training on Regional Brain volume and perfusion in older adults: the Age-Well Randomized Clinical Trial JAMA Neurol. 2022 79 1165 1174 10.1001/jamaneurol.2022.3185 36215061 9552046
N.L. Marchant et al. Effects of a mindfulness-based intervention versus Health Self-Management on subclinical anxiety in older adults with subjective cognitive decline: the SCD-Well Randomized Superiority Trial Psychother. Psychosom. 2021 90 341 350 10.1159/000515669 33873195
M. Farias E. Maraldi K.C. Wallenkampf G. Lucchetti Adverse events in meditation practices and meditation-based therapies: a systematic review Acta Psychiatr Scand. 2020 142 374 393 10.1111/acps.13225 32820538
S.B. Goldberg S.U. Lam W.B. Britton R.J. Davidson Prevalence of meditation-related adverse effects in a population-based sample in the United States Psychother. Res. 2022 32 291 305 10.1080/10503307.2021.1933646 34074221
M. Schlosser T. Sparby S. Vörös R. Jones N.L. Marchant Unpleasant meditation-related experiences in regular meditators: prevalence, predictors, and conceptual considerations Plos One 2019 14 e0216643 10.1371/journal.pone.0216643 31071152 6508707
A. Lutz et al. The protective effect of mindfulness and compassion meditation practices on ageing: hypotheses, models and experimental implementation Ageing Res. Rev. 2021 72 101495 10.1016/j.arr.2021.101495 34718153
G. Poisnel et al. The Age-Well randomized controlled trial of the medit-ageing European project: Effect of meditation or foreign language training on brain and mental health in older adults Alzheimers Dement. Transl Res. Clin. Interv 2018 4 714 723 10.1016/j.trci.2018.10.011
M. Schlosser et al. Measuring psychological mechanisms in Meditation Practice: using a Phenomenologically grounded classification system to develop theory-based Composite scores Mindfulness 2022 13 600 614 10.1007/s12671-021-01816-0
M. Schlosser N.G. Pfaff S.R. Schweinberger N.L. Marchant O.M. Klimecki The psychometric properties of the compassionate love scale and the validation of the English and German 7-item compassion for others scale (COS-7) Curr. Psychol. 2021 42 579 591 10.1007/s12144-020-01344-5
S. Sprecher B. Fehr Compassionate love for close others and humanity J. Soc. Pers. Relatsh. 2005 22 629 651 10.1177/0265407505056439
E.M. Forman et al. The Drexel defusion scale: a new measure of experiential distancing J. Context Behav. Sci. 2012 1 55 65 10.1016/j.jcbs.2012.09.001
R.A. Baer G.T. Smith J. Hopkins J. Krietemeyer L. Toney Using Self-Report Assessment methods to explore facets of mindfulness Assessment 2006 13 27 45 10.1177/1073191105283504 16443717
M.H. Davis Measuring individual differences in empathy: evidence for a multidimensional approach J. Pers. Soc. Psychol. 1983 44 113 126 1983eibb.book...D 10.1037/0022-3514.44.1.113
W.E. Mehling et al. The Multidimensional Assessment of Interoceptive Awareness (MAIA) PLOS ONE 2012 7 e48230 2012PLoSO..748230M 10.1371/journal.pone.0048230 23133619 3486814
G.V. Caprara P. Steca A. Zelli C. Capanna A New Scale for measuring adults’ prosocialness Eur. J. Psychol. Assess. 2005 21 77 89 10.1027/1015-5759.21.2.77
O.P. John S. Srivastava The Big Five Trait taxonomy: History, measurement, and theoretical perspectives Handb. Personal. Theory Res 1999 2 New York, NY, US Guilford Press 102 38
K.V. Papp D.M. Rentz I. Orlovsky R.A. Sperling E.C. Mormino Optimizing the preclinical Alzheimer’s cognitive composite with semantic processing: the PACC5 Alzheimers Dement. Transl Res. Clin. Interv 2017 3 668 677 10.1016/j.trci.2017.10.004
Goldberg, SB. et al. Is Dosage of a Meditation App Associated With Changes in Psychological Distress? It Depends on How You Ask. Clin. Psychol. Sci. 21677026241266570. https://doi.org/10.1177/21677026241266567 (2024).
K.M. Riordan et al. How often should I meditate? A randomized trial examining the role of meditation frequency when total amount of meditation is held constant J Couns Psychol. 2024 71 104 14 10.1037/cou0000725
