Exploring the Physicochemical and Antioxidant Characteristics of Honey from Eastern Morocco: Insights into Potential Health Benefits and Molecular Docking Analysis
Abeslami, Azzedine; Farissi, Hammadi; El Bachiri, Aliet al.
antioxidant activity; physicochemical properties; total phenolic content; total flavonoid content; molecular docking; DFT
Abstract :
[en] This study evaluates the physicochemical properties, phenolic and flavonoid content,
antioxidant activity, and molecular docking interactions of honey from eastern Morocco. Analysis confirmed compliance with European Commission standards, with moisture content ranging
from 15.39% to 19.74% and pH between 3.79 and 4.94. Carob honey exhibited the highest protein
content (0.42%), polyphenol concentration (720.16 mg gallic acid/kg), flavonoid content (90.5 mg
catechin/kg), and antioxidant activity (63.5% DPPH inhibition). Strong correlations were observed
between phenolic and flavonoid content and antioxidant properties. Molecular docking identified
ethyl phenylacetate and thymol as key compounds with significant interactions with cytochrome
c peroxidase, suggesting potential therapeutic effects. DFT calculations supported these findings,
indicating these compounds may enhance antioxidant activity. The study highlights the exceptional
quality and antioxidant capacity of honey from eastern Morocco, reflecting its unique floral sources
and potential as a natural source of antioxidants with therapeutic benefits.
Disciplines :
Agriculture & agronomy Chemistry
Author, co-author :
Abeslami, Azzedine; Laboratory of Environment and Applied Chemistry (LCAE), Team: Physical Chemistry of the Natural Resources and Processes, Faculty of Sciences, Mohammed First University, Oujda, Morocco
Farissi, Hammadi; Laboratory of Environment and Applied Chemistry (LCAE), Team: Physical Chemistry of the Natural Resources and Processes, Faculty of Sciences, Mohammed First University, Oujda, Morocco
El Bachiri, Ali; Laboratory of Environment and Applied Chemistry (LCAE), Team: Physical Chemistry of the Natural Resources and Processes, Faculty of Sciences, Mohammed First University, Oujda, Morocco
Sindic, Mariane; Laboratory of Agro-Food Quality and Safety, Faculty of the Agronomic Sciences, University Liege of Gembloux Agro-Bio Tech, Beekeeping Research and Information Centre (CARI), Louvain-la-Neuve, Belgium
Fauconnier, Marie-Laure ; Université de Liège - ULiège > TERRA Research Centre > Chemistry for Sustainable Food and Environmental Systems (CSFES)
Bruneau, Etienne; Beekeeping Research and Information Centre (CARI), Louvain-la-Neuve, Belgium
Talhaoui, Abdelmonaem; Laboratory of Environment and Applied Chemistry (LCAE), Team: Physical Chemistry of the Natural Resources and Processes, Faculty of Sciences, Mohammed First University, Oujda, Morocco
Language :
English
Title :
Exploring the Physicochemical and Antioxidant Characteristics of Honey from Eastern Morocco: Insights into Potential Health Benefits and Molecular Docking Analysis
Publication date :
06 September 2024
Journal title :
Agriculture
eISSN :
2077-0472
Publisher :
Multidisciplinary Digital Publishing Institute (MDPI), Switzerland
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