[en] From MeOH-soluble fraction of the flowers of Hibiscus sabdariffa (Malvaceae), one new lignan, (þ)-4-O-methyl-5 0-methoxy-secoisolariciresinol (1), together with four known compounds (2-5) were isolated. The structures were elucidated based on NMR spectroscopic analysis. The absolute configuration of 1 was determined based on the Cotton effects in the CD spectrum. Compounds 1, 3 and 4 showed antioxidant activities with the SC 50 values of 56.9, 19.3 and 22.7 mM, respectively.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Van Nguyen Thien, Truong; Faculty of Chemistry, VNUHCM-University of Science, Ho Chi Minh City, Vietnam
Thi, Lien
Do, My; Faculty of Environmental Science, Sai Gon University, Ho Chi Minh City, Vietnam
Dang, Hoang; Faculty of Chemistry, VNUHCM-University of Science, Ho Chi Minh City, Vietnam
Huynh, Ngoc; Faculty of Chemistry, VNUHCM-University of Science, Ho Chi Minh City, Vietnam
Dang, Phuc; Laboratory of Applied Physics, Advanced Institute of Materials Science, Ton Duc Thang University, Ho Chi Minh City, Vietnam ; Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam
Nguyen, Thanh; Binh Thuan Pharmaceutical and Medical Equipment Joint Stock Company (PhaPharco), Vietnam
Tran, Kim Thuy ; Université de Liège - ULiège > TERRA Research Centre ; Binh Thuan Pharmaceutical and Medical Equipment Joint Stock Company (PhaPharco), Vietnam
Nguyen, Minh; Faculty of Traditional Medicine, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam
That, Quang; Faculty of Chemistry, VNUHCM-University of Science, Ho Chi Minh City, Vietnam
Dang, Huu
Language :
English
Title :
A new lignan from the flowers of Hibiscus sabdariffa L. (Malvaceae)
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