The evolution of subjective cognition after meditation training in older people: a secondary analysis of the three-arm age-well randomized controlled trial.
[en] Aging is associated with cognitive changes, even in the absence of brain pathology. This study aimed to determine if meditation training, by comparison to active and passive control groups, is linked to changes in the perception of cognitive functioning in older adults. One hundred thirty-four healthy older participants from the Age-Well Randomized Clinical Trial were included: 45 followed a meditation training, 45 a non-native language training and 44 had no intervention. Subjective cognition was assessed at baseline and following the 18-month intervention period. Perception of attentional efficiency was assessed using internal and external Attentional Style Questionnaire (ASQ) subscale scores. Perception of global cognitive capacities was measured via the total score of Cognitive Difficulties Scale (CDS). Deltas ([posttest minus pretest scores]/standard deviation at pretest) were calculated for the analyses. Generalized mixed effects models controlling for age, sex, education and baseline scores revealed that meditation training decreased the vulnerability score toward external distractors measured by the ASQ compared to non-native language training. However, no between-groups differences on ASQ internal or CDS total scores were observed. Results suggest a beneficial effect of meditation practice on perceived management of external distracting information in daily life. Meditation training may cultivate the ability to focus on specific information (e.g., breath) and ignore stimulation from other kinds of stimuli (e.g., noise).
Disciplines :
Neurosciences & behavior
Author, co-author :
Requier, Florence ; Université de Liège - ULiège > GIGA > GIGA CRC In vivo Imaging - Aging & Memory
Demnitz-King, Harriet ; Division of Psychiatry, University College London, London, UK
Frison, Eric ; Eduwell team, Lyon Neuroscience Research Center, Lyon University, Lyon, France
Delarue, Marion ; PhIND "Physiopathology and Imaging of Neurological Disorders", Institut Blood and Brain at Caen-Normandie, Caen, France
Gonneaud, Julie ; PhIND "Physiopathology and Imaging of Neurological Disorders", Institut Blood and Brain at Caen-Normandie, Caen, France
Chételat, Gaël ; PhIND "Physiopathology and Imaging of Neurological Disorders", Institut Blood and Brain at Caen-Normandie, Caen, France
Klimecki, Olga ; Swiss Center for Affective Sciences, Department of Medicine, University of Geneva, Geneva, Switzerland
Salmon, Eric ; Université de Liège - ULiège > Département des sciences cliniques ; Université de Liège - ULiège > GIGA > GIGA CRC In vivo Imaging - Aging & Memory
Lutz, Antoine ; Eduwell team, Lyon Neuroscience Research Center, Lyon University, Lyon, France
Marchant, Natalie L ; Division of Psychiatry, University College London, London, UK
Collette, Fabienne ; Université de Liège - ULiège > GIGA > GIGA CRC In vivo Imaging - Aging & Memory ; Université de Liège - ULiège > Psychologie et Neuroscience Cognitives (PsyNCog) > Cognition et Langage
Medit-Ageing Research Group
Language :
English
Title :
The evolution of subjective cognition after meditation training in older people: a secondary analysis of the three-arm age-well randomized controlled trial.
Publication date :
17 July 2024
Journal title :
Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
Chételat, G., Lutz, A., Klimecki, O., Frison, E., Asselineau, J., Schlosser, M., Arenaza-Urquijo, E. M., Mézenge, F., Kuhn, E., Moulinet, I., Touron, E., Dautricourt, S., André, C., Palix, C., Ourry, V., Felisatti, F., Gonneaud, J., Landeau, B., Rauchs, G., & Medit-Ageing Research Group. (2022). Effect of an 18-month meditation training on regional brain volume and perfusion in older adults: The age-well randomized clinical trial. JAMA Neurology, 79(11), 1–10. https://doi.org/10.1001/jamaneurol.2022.3185
Collette, F., (2019a). Les modifications cognitives associées au vieillissement normal: d’une conception déficitaire à une vision de compensation. Revue de neuropsychologie, 11(1), 23. https://doi.org/10.3917/rne.111.0023
Collette, F., (2019b). Les modifications des processus exécutifs et de leurs substrats cérébraux avec l’avancée en âge. Revue de neuropsychologie, 11(2), 93–99. https://doi.org/10.1684/nrp.2019.0503
Costello, M. C., Madden, D. J., Shepler, A. M., Mitroff, S. R., & Leber, A. B., (2010). Age-related preservation of top-down control over distraction in visual search. Experimental Aging Research, 36(3), 249–272. https://doi.org/10.1080/0361073X.2010.484719
Demnitz-King, H., Requier, F., Whitfield, T., Schlosser, M., Gonneaud, J., Ware, C., Barnhofer, T., Coll-Padros, N., Dautricourt, S., Delarue, M., Klimecki, O. M., Paly, L., Salmon, E., Schild, E.-K., Wirth, M., Frison, E., Lutz, A., Chételat, G., Collette, F., & Marchant, N. L., (2023). Effects of meditation training and non-native language training on cognition in older adults: A secondary analysis of a randomized clinical trial. JAMA Network Open, 6(7), e2317848. https://doi.org/10.1001/jamanetworkopen.2023.17848
Devilly, G. J., & Borkovec, T. D., (2000). Psychometric properties of the credibility/expectancy questionnaire. Journal of Behavior Therapy and Experimental Psychiatry, 31(2), 73–86. https://doi.org/10.1016/S0005-7916(00)00012-4
Dufouil, C., Fuhrer, R., & Alpérovitch, A., (2005). Subjective cognitive complaints and cognitive decline: Consequence or predictor? The epidemiology of vascular aging study. Journal of the American Geriatrics Society, 53(4), 616–621. https://doi.org/10.1111/j.1532-5415.2005.53209.x
Erskine, J. A. K., Georgiou, G. J., Joshi, M., Deans, A., & Colegate, C., (2017). Ageing and thought suppression performance: Its relationship with working memory capacity, habitual thought suppression and mindfulness. Consciousness and Cognition, 53, 211–221. https://doi.org/10.1016/j.concog.2017.06.019
Felisatti, F., Chauveau, L., Marchant, N. L., Collette, F., Demnitz-King, H., Whitfield, T., Requier, F., Mézenge, F., Landeau, B., Palix, C., Haudry, S., Delarue, M., De La Sayette, V., Vivien, D., Poisnel, G., Flores, R., De Chételat, G., Gonneaud, J., Boulevard, C., & Becquerel, H., (2023). Interaction between APOE4 status and lifestyle on brain and cognitive outcomes in cognitively unimpaired older adults. medRxiv. https://doi.org/10.1101/2023.07.17.23292755
Folstein, M. F., Folstein, S. E., & Fanjiang, G., (2001). Mini-Mental State Examination: Clinical guide. Psychological Assessment Resources.
Friedman, N. P., & Miyake, A., (2004). The relations among inhibition and interference control functions: A latent-variable analysis. Journal of Experimental Psychology: General, 133(1), 101–135. https://doi.org/10.1037/0096-3445.133.1.101
Gass, C. S., Patten, B., Penate, A., & Rhodes, A., (2021). The cognitive difficulties scale (CDS): Psychometric characteristics in a clinical referral sample. Journal of the International Neuropsychological Society, 27(4), 351–364. https://doi.org/10.1017/S1355617720001058
Harada, C. N., Natelson Love, M. C., & Triebel, K. L., (2013). Normal cognitive aging. Clinics in Geriatric Medicine, 29(4), 737–752. https://doi.org/10.1016/j.cger.2013.07.002
Incagli, F., Tarantino, V., Crescentini, C., & Vallesi, A., (2020). The effects of 8-week mindfulness-based stress reduction program on cognitive control: An EEG study. Mindfulness, 11(3), 756–770. https://doi.org/10.1007/s12671-019-01288-3
Innes, K. E., Selfe, T. K., Khalsac, D. S., Kandatia, S., & Ashford, J. W., (2017). Meditation and music improve memory and cognitive function in adults with subjective cognitive decline: A pilot randomized controlled trial. Journal of Alzheimer’s Disease, 56(3), 899–916. https://doi.org/10.3233/JAD-160867
Jessen, F., Amariglio, R. E., Buckley, R. F., van der Flier, W. M., Han, Y., Molinuevo, J. L., Rabin, L., Rentz, D. M., Rodriguez-Gomez, O., Saykin, A. J., Sikkes, S. A. M., Smart, C. M., Wolfsgruber, S., & Wagner, M., (2020). The characterisation of subjective cognitive decline. Lancet Neurology, 19(3), 271–278. https://doi.org/10.1016/S1474-4422(19)30368-0
Langlois, A. S., & Belleville, S., (2014). Subjective cognitive complaint in healthy older adults: Identification of major domains and relation to objective performance. Aging, Neuropsychology & Cognition, 21(3), 257–282. https://doi.org/10.1080/13825585.2013.795928
Logan, G. D., (1985). Executive control of thought and action. Acta Psychologica, 60(2–3), 193–210. https://doi.org/10.1016/0001-6918(85)90055-1
Lutz, A., Chételat, G., Collette, F., Klimecki, O. M., Marchant, N. L., & Gonneaud, J., (2021). The protective effect of mindfulness and compassion meditation practices on ageing: Hypotheses, models and experimental implementation. Ageing Research Reviews, 72, 101495. https://doi.org/10.1016/j.arr.2021.101495
Lutz, A., Slagter, H. A., Dunne, J. D., & Davidson, R. J., (2008). Attention regulation and monitoring in meditation. Trends in Cognitive Sciences, 12(4), 163–169. https://doi.org/10.1016/j.tics.2008.01.005
Maillet, D., Yu, L., Hasher, L., & Grady, C. L., (2020). Age-related differences in the impact of mind-wandering and visual distraction on performance in a go/no-go task. Psychology and Aging, 35(5), 627–638. https://doi.org/10.1037/pag0000409
Martins, C. A. R., (2012). Silent healing: Mindfulness-based stress reduction program for older adults [ProQuest Dissertations and Theses]. http://easyaccess.lib.cuhk.edu.hk/login?url=http://search.proquest.com/docview/1086325806?accountid=10371%5Cnhttp://findit.lib.cuhk.edu.hk/852cuhk/?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&genre=dissertations+%26+theses&sid=ProQ:P
Mcalister, C., & Schmitter-Edgecombe, M., (2017). Adults with subjective cognitive concerns. The Clinical Neuropsychologist, 30(7), 1087–1103. https://doi.org/10.1080/13854046.2016.1190404
McNair, D. M., & Kahn, R. J., (1983). Self-assessment of cognitive deficits. In T., Crook, D., Ferris, & R., Bartus (Eds.), Assessment in geriatric psychopharmacology (pp. 137–143). Mark Powley Associates.
Narbutas, J., Van Egroo, M., Chylinski, D., Bahri, M. A., Koshmanova, E., Talwar, P., Besson, G., Muto, V., Schmidt, C., Luxen, A., Balteau, E., Phillips, C., Maquet, P., Salmon, E., Bastin, C., Vandewalle, G., & Collette, F., (2021). Associations between cognitive complaints, memory performance, mood, and amyloid-β accumulation in healthy amyloid negative late-midlife individuals. Journal of Alzheimer’s Disease, 83(1), 127–141. https://doi.org/10.3233/JAD-210332
Newson, R. S., & Kemps, E. B., (2006). The nature of subjective cognitive complaints of older adults. International Journal of Aging & Human Development, 63(2), 139–151. https://doi.org/10.2190/1EAP-FE20-PDWY-M6P1
Poisnel, G., Arenaza-Urquijo, E., Collette, F., Klimecki, O. M., Marchant, N. L., Wirth, M., de La Sayette, V., Rauchs, G., Salmon, E., Vuilleumier, P., Frison, E., Maillard, A., Vivien, D., Lutz, A., & Chételat, G., (2018). The age-well randomized controlled trial of the medit-ageing European project: Effect of meditation or foreign language training on brain and mental health in older adults. Alzheimer’s & Dementia, 4(1), 714–723. https://doi.org/10.1016/j.trci.2018.10.011
Rabbit, P., & Abson, V., (1991). Do older people know how good they are?British Journal of Psychology, 82(2), 137–151. https://doi.org/10.1111/j.2044-8295.1991.tb02389.x
Rabin, L. A., Smart, C. M., & Amariglio, R. E., (2017). Subjective cognitive decline in preclinical Alzheimer’s disease. Annual Review of Clinical Psychology, 13, 369–396. https://doi.org/10.1146/annurev-clinpsy-032816-045136
Reaves, S., Graham, B., Grahn, J., Rabannifard, P., & Duarte, A., (2016). Turn off the music! Music impairs visual associative memory performance in older adults. The Gerontologist, 56(3), 569–577. https://doi.org/10.1093/geront/gnu113
Reuter-Lorenz, P. A., & Park, D. C., (2014). How does it STAC up? Revisiting the scaffolding theory of aging and cognition. Neuropsychology Review, 24(3), 355–370. https://doi.org/10.1007/s11065-014-9270-9
Rey-Mermet, A., & Gade, M., (2018). Inhibition in aging: What is preserved? What declines? A meta-analysis. Psychonomic Bulletin & Review, 25(5), 1695–1716. https://doi.org/10.3758/s13423-017-1384-7
SAS Institute Inc. (2013). Base SAS®9.4 procedures guide (2nd ed.). Statistical Procedures.
Sheikh, J. I., & Yesavage, J. A., (1988). Geriatric depression scale (GDS): Recent evidence and development of a shorter version. Clinical Gerontologist: The Journal of Aging and Mental Health, 5(1–2), 165–173. https://doi.org/10.1300/J018v05n01_09
Spielberger, C. D., Gorsuch, R. L., & Lushene, R. E., (1970). STAI manual for the state-trait anxiety inventory. Self-evaluation questionnaire.
Steinberg, S. I., Negash, S., Sammel, M. D., Bogner, H., Harel, B. T., Livney, M. G., McCoubrey, H., Wolk, D. A., Kling, M. A., & Arnold, S. E., (2013). Subjective memory complaints, cognitive performance, and psychological factors in healthy older adults. American Journal of Alzheimer’s Disease & Other Dementias, 28(8), 776–783. https://doi.org/10.1177/1533317513504817
Stern, Y., Arenaza-Urquijo, E. M., Bartrés-Faz, D., Belleville, S., Cantilon, M., Chetelat, G., Ewers, M., Franzmeier, N., Kempermann, G., Kremen, W. S., Okonkwo, O., Scarmeas, N., Soldan, A., Udeh-Momoh, C., Valenzuela, M., Vemuri, P., Vuoksimaa, E., Arenaza Urquiljo, E. M., Bartrés-Faz, D., & Vuoksimaa, E., (2018). Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance. Alzheimer’s and Dementia, 16(9), 1305–1311. https://doi.org/10.1016/j.jalz.2018.07.219
Urry, H. L., & Gross, J. J., (2010). Emotion regulation in older age. Current Directions in Psychological Science, 19(6), 352–357. https://doi.org/10.1177/0963721410388395
Van Calster, L., D’Argembeau, A., & Majerus, S., (2018). Measuring individual differences in internal versus external attention: The attentional style questionnaire. Personality & Individual Differences, 128, 25–32. https://doi.org/10.1016/j.paid.2018.02.014
Verhaeghen, P., Cerella, J., Basak, C., & Bopp, K. L., (2005). Aging and varieties of cognitive control: A review of meta-analyses on resistance to interference, coordination, and task switching, and an experimental exploration of age-sensitivity in the newly identified process of focus switching. In R., Engle, G., Sedek, U., Von Hecker, & D., McIntosh (Eds.), Cognitive limitations in aging and psychopathology (pp. 160–189). Cambridge University Press. https://doi.org/10.1017/CBO9780511720413.008
Wuthrich, V. M., Johnco, C. J., & Wetherell, J. L., (2015). Differences in anxiety and depression symptoms: Comparison between older and younger clinical samples. International Psychogeriatrics, 27(9), 1523–1532. https://doi.org/10.1017/S1041610215000526
Zhang, Y., Hedo, R., Rivera, A., Rull, R., Richardson, S., & Tu, X. M., (2019). Post hoc power analysis: Is it an informative and meaningful analysis?General Psychiatry, 32(4), e100069. https://doi.org/10.1136/gpsych-2019-100069
Zlatar, Z. Z., Moore, R. C., Palmer, B. W., Thompson, W. K., & Jeste, D. V., (2014). Cognitive complaints correlate with depression rather than concurrent objective cognitive impairment in the successful aging evaluation baseline sample. Journal of Geriatric Psychiatry and Neurology, 27(3), 181–187. https://doi.org/10.1177/0891988714524628
