Article (Scientific journals)
Dopaminergic neurones: much more than dopamine?
Seutin, Vincent
2005In British Journal of Pharmacology, 146 (2), p. 167-9
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Keywords :
Dopamine/physiology; Dopamine Agents/pharmacology; Endocannabinoids/metabolism; Glutamic Acid/metabolism; Humans; Neurons/physiology
Abstract :
[en] Midbrain dopaminergic (DA) neurones sustain important physiological functions such as control of motricity, signalling of the error in prediction of rewards and modulation of emotions and cognition. Moreover, their degeneration leads to Parkinson's disease and they may be dysfunctional in other pathological states, such as schizophrenia and drug abuse. A subset of DA neurones has been known for many years to contain releasable peptides such as neurotensin and cholecystokinin. However, recent experimental evidence indicates that the phenotype of DA neurones may be much more diverse, since it is suggested that, under certain conditions, they may also release glutamate, cannabinoids and even serotonin.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Seutin, Vincent ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Pharmacologie
Language :
English
Title :
Dopaminergic neurones: much more than dopamine?
Publication date :
2005
Journal title :
British Journal of Pharmacology
ISSN :
0007-1188
Publisher :
Nature Publishing Group, London, United Kingdom
Volume :
146
Issue :
2
Pages :
167-9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 16 April 2010

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