Ethnicity/genetics; Exome/genetics; Heterozygote; Homozygote; Humans; Polymorphism, Single Nucleotide; Genetic Variation; Ethnic Groups; Exome; Biophysics; Biochemistry; Chemistry (all); General Chemistry; General Medicine
Abstract :
[en] We studied the genetic diversity of the Yakut population using exome sequencing. We performed comparative analysis of the Yakut population and the populations that are included in the "1000 Genomes" project and we identified the alleles specific to the Yakut population. We showed, that the Yakuts population is a separate cluster between Europeans and East Asians.
Disciplines :
Genetics & genetic processes
Author, co-author :
Zlobin, Alexander ; Université de Liège - ULiège > GIGA > GIGA Medical Genomics - Unit of Animal Genomics ; Novosibirsk State University, Novosibirsk, 630090, Russia. defrag12@gmail.com ; Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia. defrag12@gmail.com
Sharapov, S Sh; Novosibirsk State University, Novosibirsk, 630090, Russia ; Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia
Guryev, V P; European Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen, The Netherlands
Bevova, M R; European Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen, The Netherlands
Tsepilov, Y A; Novosibirsk State University, Novosibirsk, 630090, Russia ; Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia
Sivtseva, T M; Research Institute of Health, Ammosov North-Eastern Federal University, Yakutsk, Russia
Boyarskih, U A; Novosibirsk State University, Novosibirsk, 630090, Russia ; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia
Sokolova, E A; Novosibirsk State University, Novosibirsk, 630090, Russia ; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia
Aulchenko, Y S; Novosibirsk State University, Novosibirsk, 630090, Russia ; Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia
Filipenko, M L; Novosibirsk State University, Novosibirsk, 630090, Russia ; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia
Osakovsky, V L; Research Institute of Health, Ammosov North-Eastern Federal University, Yakutsk, Russia
Language :
English
Title :
Population specific analysis of Yakut exomes.
Publication date :
May 2017
Journal title :
Doklady. Biochemistry and Biophysics
ISSN :
1607-6729
eISSN :
1608-3091
Publisher :
Maik Nauka Publishing / Springer SBM, United States
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