Article (Scientific journals)
Immune-mediated cerebellitis following SARS-CoV-2 infection-a case report and review of the literature.
Plumacker, Florence; Lambert, Nicolas; Maquet, Pierre
2023In Journal of Neurovirology, 29 (4), p. 507 - 518
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Keywords :
COVID-19; Cerebellitis; Coronavirus; Neurological manifestation; Post-infectious; SARS-CoV-2; Humans; COVID-19/complications; Neurology; Neurology (clinical); Cellular and Molecular Neuroscience; Virology
Abstract :
[en] The coronavirus disease 2019 (COVID-19) can be associated with a wide variety of neurological manifestations. Some of these manifestations might result from the ongoing systemic inflammatory state, but the pathophysiology of specific neurologic involvement is still unclear. In this article, we report a patient who developed an isolated cerebellar syndrome 9 weeks after an episode of COVID-19. The reverse-transcriptase polymerase chain reaction (RT-PCR) for SARS-CoV-2 was positive on cerebrospinal fluid (CSF). A post-infectious-autoimmune-cerebellitis following COVID-19 was suspected, and the patient was treated with corticosteroids, leading to a complete recovery within a few weeks. We review the other cases of COVID-19-associated cerebellar syndrome reported so far and discuss the potential pathophysiological mechanisms underlying this neurologic manifestation.
Disciplines :
Neurology
Author, co-author :
Plumacker, Florence ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de neurologie
Lambert, Nicolas  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de neurologie
Maquet, Pierre  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de neurologie
Language :
English
Title :
Immune-mediated cerebellitis following SARS-CoV-2 infection-a case report and review of the literature.
Publication date :
August 2023
Journal title :
Journal of Neurovirology
ISSN :
1355-0284
eISSN :
1538-2443
Publisher :
Springer Science and Business Media Deutschland GmbH, United States
Volume :
29
Issue :
4
Pages :
507 - 518
Peer reviewed :
Peer Reviewed verified by ORBi
Funding text :
We thank the patient’s family for their understanding and support.
Available on ORBi :
since 05 February 2024

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