Antidepressive Agents; Humans; Diabetes Mellitus, Type 2/complications/drug therapy; Depression/drug therapy; Quality of Life; Obesity/complications; Antidepressive Agents/adverse effects; Antidepressant; Depression; Diabetes; Metabolic syndrome; SSRI; Tricyclics; Weight Gain
Abstract :
[en] Metabolic disorders (dysglycaemia, dyslipidaemia, metabolic syndrome) may occur or worsen with antidepressants. Even if the metabolic risk appears lower with antidepressants than with certain atypical antipsychotics, it should not be neglected in clinical practice, especially with antidepressants that are associated with weight gain. Metabolic disorders may occur with both selective serotonin reuptake inhibitors and tricyclics, but with some between-molecule differences within each pharmacological family. Besides potential deleterious effects of medications, the psychiatric population is also exposed to bad lifestyle habits (unhealthy diet and sedentary life) and poor medication compliance, which all together could also contribute to enhance the risk of metabolic disorders and cardiovascular complications. Facing such a complex situation, it is not easy to individualize the metabolic risk inherent to antidepressants, also because an effective management of the depression could improve both the quality of life and the adherence to a better lifestyle.
This website uses cookies to improve user experience. Read more
Save & Close
Accept all
Decline all
Show detailsHide details
Cookie declaration
About cookies
Strictly necessary
Performance
Strictly necessary cookies allow core website functionality such as user login and account management. The website cannot be used properly without strictly necessary cookies.
This cookie is used by Cookie-Script.com service to remember visitor cookie consent preferences. It is necessary for Cookie-Script.com cookie banner to work properly.
Performance cookies are used to see how visitors use the website, eg. analytics cookies. Those cookies cannot be used to directly identify a certain visitor.
Used to store the attribution information, the referrer initially used to visit the website
Cookies are small text files that are placed on your computer by websites that you visit. Websites use cookies to help users navigate efficiently and perform certain functions. Cookies that are required for the website to operate properly are allowed to be set without your permission. All other cookies need to be approved before they can be set in the browser.
You can change your consent to cookie usage at any time on our Privacy Policy page.