[en] [en] BACKGROUND: Granulosa cell tumours are rare ovarian malignancies accounting for 2% to 5% of ovarian tumours. They are characterized by late recurrences, with the latest recurrence reported 37 years after first diagnosis.
CASE: A 73-year-old woman who had surgery for a granulosa cell tumour in her early 30s and who presented with a recurrence 40 years later.
CONCLUSION: Patients and their physicians should be made aware that there is a potential for a granulosa cell tumour to recur many years in the future.
Disciplines :
Oncology
Author, co-author :
East, Nathalie; Department of Gynecology Oncology, CHUM, Notre-Dame Hospital, Montreal QC
Alobaid, Abdulaziz; Department of Gynecology Oncology, CHUM, Notre-Dame Hospital, Montreal, Canada
Goffin, Frédéric ; Centre Hospitalier Universitaire de Liège - CHU > > Service de gynécologie-obstétrique (CHR) ; Department of Gynecology Oncology, CHUM, Notre-Dame Hospital, Montreal, Canada
Ouallouche, Karim; Department of Pathology, CHUM, Notre-Dame Hospital, Montreal, Canada
Gauthier, Philippe; Department of Gynecology Oncology, CHUM, Notre-Dame Hospital, Montreal, Canada
Language :
English
Title :
Granulosa cell tumour: a recurrence 40 years after initial diagnosis.
Dr Goffin is supported by the FNRS (Fonds National de la Recherche Scientifique, Brussels, Belgium), the CHU of Liege (Mandat de Recherche Clinique), and the Fondation Leon Fredericq. The next-of-kin of the woman whose story is told in this case report has provided signed perrnission for its publication.
Segal R, DePetrillo AD, Thomas G. Clinical review of adult granulosa cell tumors of the ovary. Gynecol Oncol 1995;56:338-44.
Hines JF, Khalifa MA, Moore JL, Fine KP, Lage JM, Barnes W A. Recurrent granulosa cell tumor of the ovary 37 years after initial diagnosis: a case report and review of the literature. Gynecol Oncol 1996;60:484-8.
Schumer ST, Cannistra SA. Granulosa cell tumor of the ovary. J Clin Oncol 2003;21 (6):1180-9.
Singh-Ranger G, Sharp A, Crinnin JN. Recurrence of granulosa cell tumor after thirty years with small bowel obsrruction. 1nt Semin Surg Oncol 2004;11;1(1):4.
Ifaturati O, Cracker SG. Ovarian granulosa cell tumor recurring 36 years after primary treatment.J Obstet Gynaecol 2004;24(3):331-2.
