Analyzing the Bioactive Properties and Volatile Profiles Characteristics of Opuntia dillenii: Exploring its Potential for Pharmacological Applications.
El Hassania, Loukili; Mounime, Kadi; Elbouzidi, Amineet al.
2024 • In Chemistry and Biodiversity, p. 202301890
Opuntia dillenii; antioxidant and Anti-inflammatory activity; oil; phenolic compounds; volatile compounds; Molecular Biology; Molecular Medicine; General Chemistry; Biochemistry; General Medicine; Bioengineering
Abstract :
[en] In this investigation, the study focused on the chemical constitution and the antioxidative as well as anti-inflammatory characteristics of oils and pulpy variants (Imatchan (IM), Harmocha (HA), and Aknari (AK)) sourced from O. dillenii. This inquiry encompassed both in vitro and in silico analyses. High-performance liquid chromatography (HPLC) was employed to ascertain the phenolic constituents, while gas chromatography-mass spectrometry (GC-MS) methodologies. were applied to discern the volatile makeup. The anti-inflammatory activity was examined using BSA and LOX. Molecular docking methods assessed the antioxidant and anti-inflammatory properties. According to HPLC findings, the most abundant compounds detected in AKO and IMO cultivars were quercetin 3-O-β-D-glucoside followed by vanillic acid, ferulic acid and tyrolsol. The DPPH IC50 for AK, HA and IM were 38.41±1.54, 42.24±0.29 and 15.17±1.28 mg/mL, respectively. The AK, HA and IM O. dillenii oils were effective in their anti-inflammatory activity. Molecular docking of O. dillenii oils phenolic compounds was conducted to determine the possible targeted proteins by the phenolic compounds in O. dillenii's compounds. Overall, these fruits demonstrated the potential for new ingredients for culinary or pharmaceutical applications, providing value to these natural species that can flourish in arid conditions.
Disciplines :
Agriculture & agronomy Chemistry
Author, co-author :
El Hassania, Loukili; Mohammed First University Oujda, chemistry, Oujda, Oujda, MOROCCO
Mounime, Kadi; Mohammed First University Oujda, chemistry, Oujda, Oujda, MOROCCO
Elbouzidi, Amine; Mohammed First University Oujda, chemistry, Oujda, Oujda, MOROCCO
Taibi, Mohamed; Mohammed First University Oujda, chemistry, Oujda, Oujda, MOROCCO
Addi, Mohamed; Mohammed First University Oujda, enviromental sciences, Oujda, Oujda, MOROCCO
Fauconnier, Marie-Laure ; Université de Liège - ULiège > TERRA Research Centre > Chemistry for Sustainable Food and Environmental Systems (CSFES)
Language :
English
Title :
Analyzing the Bioactive Properties and Volatile Profiles Characteristics of Opuntia dillenii: Exploring its Potential for Pharmacological Applications.
K. Hirasa, M. Takemasa, Spice science and technology CRC Press, 1998
I. Karmakar, N. Dolai, P. Saha, N. Sarkar, A. Bala, P. K. Haldar, Orient. Pharm. Exp. Med. 2011, 11 (4), 221–228.
A. Scalbert, “Fruits et légumes, polyphénols et santé.” Professeur agrégée (Laboratoire des maladies métaboliques et micronutriments, INRA, centre de recherche de Clermont-Ferrand/Theix), relu par Ed: Florentin (2004): 239–253.
F. Visioli, A. Romani A, N. Mulinacci, S. Zarini, D. Conte, F. F. Vincieri, C. Galli, J. Agric. Food Chem. 1999, 47 (8), 3397–3401.
N. Chougui, A. Tamendjari, W. Hamidj, S. Hallal, A. Barras, T. Richard, R. Larbat, Food Chem. 2013, 139 (1-4), 796–803.
M. Kaur, A. Kaur, R. Sharma, J. Appl. Pharmacol. 2012, 2 (7), 15–18.
M. Bouhrim, H. Ouassou, M. Choukri, H. Mekhfi, A. Ziyyat, A. Legssyer, M. Bnouham, Asian Pac. J. Trop. Med. 2018, 8 (5), 254.
H. Chahdoura, J. C. Barreira, V. Fernández-Ruiz, P. Morales, R. Calhelha, C. Flamini, G. M. Soković, I. C. Ferreira, L. Achour, Food Funct. 2016, 7 (3), 1458–1467.
W. Schwab, R. Davidovich-Rikanati, E. Lewinsohn, Plant J. 2008, 54 (4), 712–732.
A. K. Hjelmeland, S. E. Ebeler, Am. J. Enol. Vitic. 2015, 66 (1), 1–11.
B. de Ancos, E. Ibanez, G. Reglero, M. P. Cano, J. Agric. Food Chem. 2000, 48 (3), 873–879.
M. N. Khalil, M. I. Fekry, M. A. Farag, Food Chem. 2017, 217, 171–181.
B. G. Defilippi, D. Manríquez, K. Luengwilai, M. González-Agüero, Adv. Bot. Res. 2009, 50, 1–37.
H. Chahdoura, J. C. Barreira, L. Barros, M. I. Dias, R. C. Calhelha, G. Flamini, M. Soković, L. Achour, I. C. Ferreira, LWT. 2019, 105, 57–65.
P. Zito, M. Sajeva, M. Bruno, S. Rosselli, A. Maggio, F. Senatore, Nat. Prod. Res. 2013, 27 (14), 1305–1314.
G. Al-Naqeb, C. Cafarella, E. Aprea, G. Ferrentino, A. Gasparini, C. Buzzanca, G. Micalizzi, P. Dugo, L. Mondello, F. Rigano, Food 2023, 12(3), 618.
E. H. Loukili, B. Bouchal, M. Bouhrim, F. Abrigach, M. Genva, K. Zidi, M. Bnouham, M. Bellaoui, B. Hammouti, M. Addi, M. Ramdani, J. Food Qual. 2022, 1–15.
J. Katanić, F. Yousfi, M. C. Caruso, S. Matić, D. M. Monti, E. H. Loukili, T. F. Boroja, V. Mihailović, F. Galgano, P. Imbimbo, G. Petruk, M. Bouhrim, M. Bnouham, M. Ramdani, Food Biosci. 2019, 30, 100410.
B. Ali, Z. Abderrahim, M. Hassane, S. Marianne, F. Marie-Laure, L. Abdelkhaleq, A. Mohammed, B. Mohamed, J. Pharmacopunct. 2022, 25 (2), 121.
N. Chougui, A. Tamendjari W Hamidj S Hallal, A. Barras T Richard R Larbat, Food Chem. 2013, 139 (1-4), 796–803.
H. Jick, The Lancet. 1994, 343 (8900), 769–772.
P. J. Barnes, Clin. Sci. 1998, 94 (6), 557–572.
C.-H. Yoon, S.-J. Chung, S.-W. Lee, Y.-B. Park, S.-K. Lee, M.-C. Park, Revue du rhumatisme. 2013, 80 (3), 271–278.
M. Gupta, T. Bhalla, G. Gupta, C. Mitra, K. Bhargava, J. Pharmacol. 1971, 21 (3), 377–382.
A. García-Lafuente, E. Guillamón, A. Villares, M. A. Rostagno, J. A. Martínez, J. Inflamm. Res. 2009, 58 (9), 537-552.
A. Pasdaran, D. Sheikhi, The Microbiology of Respiratory System Infections. 2016, 237–261.
S. Baylac, P. Racine, Int. J. Aromather. 2003, 13 (2–3), 138-142.
H. D. S. M. Perera, J. K. R. R. Samarasekera, S. M. Handunnetti, O. V. D. S. J. Weerasena, Ind. Crops Prod. 2016, 94, 610–620.
P. Siddhuraju, K. Becker, Food Chem. 2007, 101 (1), 10–19.
P.-G. Pietta, J. Nat. Prod. 2000, 63 (7), 1035–1042.
C.-A. Calliste, P. Trouillas, D.-P. Allais, A. Simon, J.-L. Duroux, J. Agric. Food Chem. 2001, 49 (7), 3321–332.
S. Kadda, A. Belabed, E. H. Loukili, B. Hammouti, S. Fadlaoui, Environ. Sci. Pollut. Res. Int. 2022, 1–9.
S. Haddou, E. H. Loukili, A. Hbika, A. Chahine, B. Hammouti, Mater. Today: Proc. 2023, 72, 3896–3903.
E. H. Loukili, F. Abrigach, M. Bouhrim, M. Bnouham, M.-L. Fauconnier, M. Ramdani, J. Chem. 2021, 2021, 1–11.
E. H. Loukili, S. Ouahabi, A. Elbouzidi, M. Taibi, M. I. Yahyaoui, A. Asehraou, A. Azougay, A. Saleh, O. Al Kamaly, M. K. Parvez, Plants. 2023, 12(19), 3376.
H. Laaroussi, A. Aouniti, B. Hafez, O. Mokhtari, R. Sheikh, I. Hamdani, I. Rahhou, E. H. Loukili, C. Belbachir, B. Hammouti, Int. J. Corros. Scale Inhib. 2022, 11(4), 1539–1556.
S. Haddou, A. Elrherabi, E. H. Loukili, R. Abdnim, A. Hbika, M. Bouhrim, O. Al Kamaly, A. Saleh, A. A. Shahat, M. Bnouham, Molecules. 2023, 29 (1), 93.
A. Elbouzidi, M. Taibi, H. Ouassou, S. Ouahhoud, D. Ou-Yahia, E. H. Loukili, M. Aherkou, F. Mansouri, N. Bencheikh, S. Laaraj, Pharmaceuticals. 2023, 16(6), 840.
M. Oyaizu, JJ Nut Diet 1986, 44 (6), 307–315.
T. C. Dinis, V. M. Madeira, L. M. Almeida, Arch. Biochem. Biophys. 1994, 315 (1), 161–169.
G. Nikhila, G. Sangeetha, J. Med. Plants Res. 2015, 9 (1), 1–7.
B. Kar, R. S. Kumar, I. Karmakar, N. Dola, A. Bala, U. K. Mazumder, P. K. Hadar, Asian Pac. J. Trop. Med. 2012, 2 (2), S976–S980.
F. Nea, E. A. Tanoh, E. L. Wognin, T. K. Kemene, M. Genva, M. Saive, Z. F. Tonzibo, M.-L. Fauconnier, Ind. Crops Prod. 2019, 141, 111766.
P. Banerjee, A. O. Eckert, A. K. Schrey, R. Preissner, Nucleic Acids Res. 2018, 46(W1), W257–W263.
M. A. Aboul-Soud, H. Ennaji, A. Kumar, M. A. Alfhili, A. Bari, M. Ahamed, M. Chebaibi, M. Bourhia, F. Khallouki, K. M. Alghamdi, Antioxidants. 2022, 11(8), 1514.
F. E.-Z. Amrati, M. Slighoua, I. Mssillou, M. Chebaibi, R. Galvão de Azevedo, S. Boukhira, K. Moslova, O. Al Kamaly, A. Saleh, A. Correa de Oliveira, Separations. 2023, 10(3), 172.
S. Ouahabi, E. H. Loukili, N. E. Daoudi, M. Chebaibi, M. Ramdani, I. Rahhou, M. Bnouham, M.-L. Fauconnier, B. Hammouti, L. Rhazi, Mar. Drugs. 2023, 21 (7), 372.
