Benin; antibiotic prophylaxis practices; beliefs; cesarean section; healthcare professionals; knowledge; Microbiology; Biochemistry; Pharmacology, Toxicology and Pharmaceutics (all); Microbiology (medical); Infectious Diseases; Pharmacology (medical); General Pharmacology, Toxicology and Pharmaceutics
Abstract :
[en] A low adherence to recommendations on antibiotic prophylaxis has been reported worldwide. Since 2009, cesarean sections have been performed under user fee exemption in Benin with a free kit containing the required supplies and antibiotics for prophylaxis. Despite the kit, the level of antibiotic prophylaxis achievement remains low. We conducted a convergent parallel design study in 2017 using a self-administered questionnaire and interviews to assess the knowledge and explore the beliefs of healthcare professionals regarding antibiotic prophylaxis in three hospitals. Of the 35 participants, 33 filled out the questionnaire. Based on the five conventional criteria of antibiotic prophylaxis, the mean level of knowledge was 3.3 out of 5, and only 15.2% scored 5 out of 5. From the verbatim of 19 interviewees, determinants such as suboptimal patient status health, low confidence in antibiotics, some disagreement with the policy, inappropriate infrastructures and limited financial resources in hospitals, poor management of the policy in the central level, and patient refusal to buy antibiotics can explain poor practices. Because of the dysfunction at these levels, the patient becomes the major determinant of adequate antibiotic prophylaxis. Policymakers have to consider these determinants for improving antibiotic prophylaxis in a way that ensures patient safety and reduces the incidence of antimicrobial resistance.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Dohou, Angèle Modupè ; Louvain Drug Research Institute, Université Catholique de Louvain, Avenue Emmanuel Mounier 73, 1200 Brussels, Belgium ; Faculté des Sciences de la Santé, Université d'Abomey Calavi, Cotonou 01 BP 188, Benin
Buda, Valentina Oana ; Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania
Anagonou, Severin; Faculté des Sciences de la Santé, Université d'Abomey Calavi, Cotonou 01 BP 188, Benin
Van Bambeke, Françoise ; Louvain Drug Research Institute, Université Catholique de Louvain, Avenue Emmanuel Mounier 73, 1200 Brussels, Belgium
UCL - Université Catholique de Louvain ARES - Académie de Recherche et d'Enseignement Supérieur
Funding text :
Funding: This work was funded in frame of PhD research by Commission de l’Action International of Université catholique de Louvain, Belgium and Académie de la Recherche et d’Enseignement Supérieur, Belgium.
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