Global and regional burden of chronic respiratory disease in 2016 arising from non-infectious airborne occupational exposures: a systematic analysis for the Global Burden of Disease Study 2016.
COPD; occupational asthma; occupational exposure; pneumoconiosis; work; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Asthma/epidemiology; Chronic Disease; Disabled Persons/statistics & numerical data; Female; Global Burden of Disease/statistics & numerical data; Global Burden of Disease/trends; Global Health/statistics & numerical data; Global Health/trends; Humans; Male; Middle Aged; Occupational Diseases/epidemiology; Occupational Exposure/adverse effects; Occupational Exposure/statistics & numerical data; Pneumoconiosis/epidemiology; Pulmonary Disease, Chronic Obstructive/epidemiology; Quality-Adjusted Life Years; Respiration Disorders/epidemiology; Risk Assessment; Risk Factors; Sex Distribution; Socioeconomic Factors; Young Adult; Life Expectancy; Asthma; Disabled Persons; Global Burden of Disease; Global Health; Occupational Diseases; Pulmonary Disease, Chronic Obstructive; Respiration Disorders; Public Health, Environmental and Occupational Health
Abstract :
[en] [en] OBJECTIVES: This paper presents detailed analysis of the global and regional burden of chronic respiratory disease arising from occupational airborne exposures, as estimated in the Global Burden of Disease 2016 study.
METHODS: The burden of chronic obstructive pulmonary disease (COPD) due to occupational exposure to particulate matter, gases and fumes, and secondhand smoke, and the burden of asthma resulting from occupational exposure to asthmagens, was estimated using the population attributable fraction (PAF), calculated using exposure prevalence and relative risks from the literature. PAFs were applied to the number of deaths and disability-adjusted life years (DALYs) for COPD and asthma. Pneumoconioses were estimated directly from cause of death data. Age-standardised rates were based only on persons aged 15 years and above.
RESULTS: The estimated PAFs (based on DALYs) were 17% (95% uncertainty interval (UI) 14%-20%) for COPD and 10% (95% UI 9%-11%) for asthma. There were estimated to be 519 000 (95% UI 441,000-609,000) deaths from chronic respiratory disease in 2016 due to occupational airborne risk factors (COPD: 460,100 [95% UI 382,000-551,000]; asthma: 37,600 [95% UI 28,400-47,900]; pneumoconioses: 21,500 [95% UI 17,900-25,400]. The equivalent overall burden estimate was 13.6 million (95% UI 11.9-15.5 million); DALYs (COPD: 10.7 [95% UI 9.0-12.5] million; asthma: 2.3 [95% UI 1.9-2.9] million; pneumoconioses: 0.58 [95% UI 0.46-0.67] million). Rates were highest in males; older persons and mainly in Oceania, Asia and sub-Saharan Africa; and decreased from 1990 to 2016.
CONCLUSIONS: Workplace exposures resulting in COPD, asthma and pneumoconiosis continue to be important contributors to the burden of disease in all regions of the world. This should be reducible through improved prevention and control of relevant exposures.
Khosravi, Mohammadhossein ; Université de Liège - ULiège > GIGA > GIGA Consciousness - Coma Science Group
Language :
English
Title :
Global and regional burden of chronic respiratory disease in 2016 arising from non-infectious airborne occupational exposures: a systematic analysis for the Global Burden of Disease Study 2016.
Deakin University BMGF - Bill and Melinda Gates Foundation Ministry of Education, Science and Technological Development Public Health Agency of Canada XMUM - Xiamen University Malaysia FEDER - Federación Española de Enfermedades Raras Generalitat Valenciana
Funding text :
Funding The overall gBD study is partly funded by the Bill & Melinda gates Foundation. The work reported in this paper was partly supported by funding from the World health Organization. The funders had no role in the study design, data collection, data analysis, data interpretation or writing of the report. The authors had access to the data in the study and the final responsibility to submit the paper.Competing interests caTa reports personal fees from Johnson & Johnson (Philippines), inc., outside the submitted work. nK reports personal fees from Junpukai Foundation and softbank, co.; and grants from Fujitsu, lTD, Fujitsu software Technologies, lTD and softbank, co., outside the submitted work. JK reports grants from Merck Pharmaceuticals, outside the submitted work. TJM reports grants from cancer Foundation Finland sr., during the conduct of the study.
Fishwick D, Sen D, Barber C, et al. Occupational chronic obstructive pulmonary disease: A standard of care. Occup Med 2015; 65: 270-82.
Omland Oyvind, Würtz ET, Aasen TB, et al. Occupational chronic obstructive pulmonary disease: A systematic literature review. Scand J Work Environ Health 2014; 40: 19-35.
Tarlo S, Malo J. Fourth jack Pepys workshop on asthma in the workplace participants. An official American thoracic Society proceedings: work-related asthma and airway diseases. presentations and discussion from the fourth jack Pepys workshop on asthma in the workplace. Ann Am Thorac Soc 2013; 10: S17-S2.
Blanc PD. Occupation and COPD: A brief review. J Asthma 2012; 49: 2-4.
Blanc PD, Iribarren C, Trupin L, et al. Occupational exposures and the risk of COPD: dusty trades revisited. Thorax 2009; 64: 6-12.
R ushton L. Occupational causes of chronic obstructive pulmonary disease. Rev Environ Health 2007; 22: 195-212.
Karjalainen A, Kurppa K, Martikainen R, et al. Exploration of asthma risk by occupation-extended analysis of an incidence study of the Finnish population. Scand J Work Environ Health 2002; 28: 49-57.
Karjalainen A, Kurppa K, Martikanen R, et al. Work is related to a substantial portion of adult-onset asthma incidence in the Finnish population. Am J Respir Crit Care Med 2001; 164: 565-8.
Kogevinas M, Zock J-P, Jarvis D, et al. Exposure to substances in the workplace and new-onset asthma: An international prospective population-based study (ECRHS-II ). The Lancet 2007; 370: 336-41.
E isner MD, Anthonisen N, Coultas D, et al. An official American thoracic Society public policy statement: novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2010; 182: 693-718.
Blackley DJ, Halldin CN, Laney AS. Continued Increase in Prevalence of Coal Workers' Pneumoconiosis in the United States, 1970-2017. Am J Public Health 2018; 108: 1220-2.
H oy RF, Baird T, Hammerschlag G, et al. Artificial stone-Associated silicosis: A rapidly emerging occupational lung disease. Occup Environ Med 2018; 75: 3-5.
N elson DI, Concha-Barrientos M, Driscoll T, et al. The global burden of selected occupational diseases and injury risks: methodology and summary. Am J Ind Med 2005; 48: 400-18.
Driscoll T, Nelson DI, Steenland K, et al. The global burden of non-malignant respiratory disease due to occupational airborne exposures. Am J Ind Med 2005; 48: 432-45.
L im SS, Vos T, Flaxman AD, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: A systematic analysis for the global burden of disease study 2010. The Lancet 2012; 380: 2224-60.
G BD. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: A systematic analysis for the global burden of disease study 2013. Lancet 2015; 388: 1659-724.
Forouzanfar MH, Afshin A, Alexander LT, et al. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: A systematic analysis for the global burden of disease study 2015. Lancet 2016; 388: 1659-724.
G akidou E, Afshin A, Abajobir AA, et al. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: A systematic analysis for the global burden of disease study 2016. Lancet 2017; 390: 1345-422.
S tanaway JD, Afshin A, Gakidou E, et al. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: A systematic analysis for the global burden of disease study 2017. Lancet 2018; 392: 1923-94.
G BD 2016 Occupational Carcinogens Collaborators. Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens: A systematic analysis for the global burden of disease study 2016. Occup Environ Med 2020; 77: 151-9.
G BD 2016 Occupational Risk Factors Collaborators. Global and regional burden of disease and injury in 2016 arising from occupational exposures: A systematic analysis for the global burden of disease study 2016. Occup Environ Med 2020; 77: 133-41.
I nstitute for Health Metrics and Evaluation. GBD compare. Seattle, WA: IHME, University of Washington, 2017.
I nternational Labour Office. ILOSTAT database. Geneva: ILO, 2015.
L evin M. The occurrence of lung cancer in man. Acta Unio Internationalis Contra Cancrum 1959; 9: 531-41.
Weinmann S, Vollmer WM, Breen V, et al. Copd and occupational exposures: A case-control study. J Occup Environ Med 2008; 50: 561-9.
Vestbo J, Hurd SS, Agustí AG , et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2013; 187: 347-65.
Kauppinen T, Toikkanen J, Pedersen D, et al. Occupational exposure to carcinogens in the European Union. Occup Environ Med 2000; 57: 10-18.
Kogevinas M, Anto J, Sunyer J, et al. Occupational asthma in Europe. Lancet 1999; 353: 1750-4.
Wang H, Abajobir AA, Abate KH, et al. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: A systematic analysis for the global burden of disease study 2016. The Lancet 2017; 390: 1084-150.
S oriano JB, Abajobir AA, Abate KH, et al. Global, regional, and national deaths, prevalence, disability-Adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015: A systematic analysis for the global burden of disease study 2015. Lancet Respir Med 2017; 5: 691-706.
Balmes J, Becklake M, Blanc P, et al. American thoracic Society statement: occupational contribution to the burden of airway disease. Am J Respir Crit Care Med 2003; 167: 787-97.
Meldrum Met al. The role of occupation in the development of chronic obstructive pulmonary disease (COPD). Occup Environ Med 2005; 62: 212-4.
Mehta AJ, Miedinger D, Keidel D, et al. Occupational exposure to dusts, gases, and fumes and incidence of chronic obstructive pulmonary disease in the Swiss cohort study on air pollution and lung and heart diseases in adults. Am J Respir Crit Care Med 2012; 185: 1292-300.
L ytras T, Kogevinas M, Kromhout H, et al. Occupational exposures and 20-year incidence of COPD: The European community respiratory health survey. Thorax 2018; 73: 1008-15.
Würtz ET, Schlünssen V, Malling TH, et al. Occupational COPD among Danish never-smokers: A population-based study. Occup Environ Med 2015; 72: 456-9.
H ooper R, Burney P, Vollmer WM, et al. Risk factors for COPD spirometrically defined from the lower limit of normal in the BOLD project. Eur Respir J 2012; 39: 1343-53.
Darnton A, Hodgson J, Benson P, et al. Mortality from asbestosis and mesothelioma in Britain by birth cohort. Occup Med 2012; 62: 549-52.
World Health Organization. Who mortality database. Geneva: WHO, 2016.
Baussano I, Nunn P, Williams B, et al. Tuberculosis among health care workers. Emerg Infect Dis 2011; 17: 488-94.
Traboulsi H, Guerrina N, Iu M, et al. Inhaled pollutants: The molecular scene behind respiratory and systemic diseases associated with ultrafine particulate matter. Int J Mol Sci 2017; 18: 243.