Intraoral low-temperature degradation of monolithic zirconia dental prostheses: 5-year results of a prospective clinical study with ex vivo monitoring.
[en] [en] OBJECTIVES: To investigate the 5-year intraoral evolution and kinetics of low-temperature degradation (LTD) of second-generation monolithic prostheses made of 3% molar yttrium-doped tetragonal zirconia polycrystal (3Y-TZP) and the influence of masticatory mechanical stresses and glaze layer on this evolution.
METHODS: A total of 101 posterior tooth elements were included in this prospective clinical study, which comprised ex vivo LTD monitoring (at baseline, 6 months, 1 year, 2 years, 3 years, and 5 years) using Raman spectroscopy (n = 2640 monoclinic phase measurement points per evaluation time) and scanning electron microscopy (SEM). Four types of areas (1-2 mm2 surface, six on molars, and four on premolars) were analysed on each element surface: occlusal, axial, glazed, or unglazed. Raman mapping, high-resolution SEM, and focused ion beam-SEM were performed on selected samples.
RESULTS: The dental prostheses developed a tetragonal-to-monoclinic transformation at the extreme surface of the material after six months in a buccal environment, and this process increased significantly over time. Over the five years of monitoring, the transformation developed nonuniformly with the presence of localised clusters of monoclinic grains. Tribological stresses generate grain pull-out from these clusters, which may raise questions regarding the release of 3Y-TZP nanoparticles into the body. The prosthesis fracture rate was 4.5% after 5 years.
SIGNIFICANCE: LTD developed in vivo on the surfaces of 3Y-TZP dental prostheses and progressed slowly but significantly over time, up to 5 years investigation. However, the effects of aging on the failure rate recorded and of zirconia nanoparticles released into the body require further investigation.
Research Center/Unit :
d‐BRU - Dental Biomaterials Research Unit - ULiège
Disciplines :
Dentistry & oral medicine
Author, co-author :
KOENIG, Vinciane ; Centre Hospitalier Universitaire de Liège - CHU > > Service prothèse fixée
Douillard, T; Université de Lyon, INSA Lyon, CNRS, MATEIS, UMR 5510, F-69621 Villeurbanne, France
Chevalier, J; Université de Lyon, INSA Lyon, CNRS, MATEIS, UMR 5510, F-69621 Villeurbanne, France
Amiard, F; Institut des Molécules et Matériaux du Mans (IMMM - UMR6283), Université du Mans, avenue Olivier Messiaen, 72085 Cedex 9 Le Mans, France
Lamy de la Chapelle, M; Institut des Molécules et Matériaux du Mans (IMMM - UMR6283), Université du Mans, avenue Olivier Messiaen, 72085 Cedex 9 Le Mans, France
Le Goff, S; Unité de Recherches en Biomatériaux Innovants et Interfaces (URB2i) - EA4462, Faculté de Chirurgie Dentaire, Université Paris Descartes, Sorbonne Paris-Cité, Montrouge 92120, France
Vanheusden, Alain ; Centre Hospitalier Universitaire de Liège - CHU > > Service prothèse fixée
Dardenne, Nadia ; Université de Liège - ULiège > Département des sciences de la santé publique
Wulfman, C; Dental Biomaterials Research Unit (d-BRU), University of Liège (ULiège), 45 Quai G. Kurth, Liège 4020, Belgium, Unité de Recherches en Biomatériaux Innovants et Interfaces (URB2i) - EA4462, Faculté de Chirurgie Dentaire, Université Paris Descartes, Sorbonne Paris-Cité, Montrouge 92120, France
Mainjot, Amélie ; Centre Hospitalier Universitaire de Liège - CHU > > Service prothèse fixée
Language :
English
Title :
Intraoral low-temperature degradation of monolithic zirconia dental prostheses: 5-year results of a prospective clinical study with ex vivo monitoring.
The authors declare that they have no competing interests related to the authorship and/or publication of this article. The authors thank 3 M for providing the restorations used in this study and for the partial funding. The company had no authority over the study design and did not influence the decision to submit the report for publication. We would also like to thank the Consortium Lyon Saint-Etienne de Microscopie (www.clym.fr) for providing access to the FIB/SEM.
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