Treatment of ocular hypertension by adrenalin and diverse sympathomimetic amines.

1. 1. The reduction of ocular tension effected by l-adrenalin in open-angle glaucoma is due to a lessened production of aqueous and not to any increased facility of drainage. 2. 2. The reduction of ocular tension by noradrenalin is less than that achieved by l-adrenalin, and the action of d-adrenalin and adrenalone is practically nil. 3. 3. Aleudrine, though not a vasoconstrictor, acts like l-adrenalin in reducing ocular tension. Since aleudrine also induces no mydriasis it may be eventually of some value in narrow-angle glaucoma, but the drug has the great disadvantage of provoking tachycardia. 4. 4. The advantages accruing from the simultaneous use of remedies facilitating aqueous drainage and reducing aqueous formation are emphasized. © 1955.