Article (Scientific journals)
Adenomyosis and Infertility: A Literature Review.
Pados, George; Gordts, Stephan; Sorrentino, Felice et al.
2023In Medicina, 59 (9), p. 1551
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Keywords :
adenomyosis; classification; diagnosis; infertility; pathogenesis; treatment
Abstract :
[en] Background and Objectives: Adenomyosis (the presence of ectopic endometrial glands and stroma below the endometrial-myometrial junction) is a benign condition which is increasingly diagnosed in younger women suffering from infertility. The aim of this narrative review was to study the pathophysiology and prevalence of adenomyosis, the mechanisms causing infertility, treatment options, and reproductive outcomes in infertile women suffering from adenomyosis. Materials and Methods: A literature search for suitable articles published in the English language was performed using PubMed from January 1970 to July 2022. Results: The literature search retrieved 50 articles that met the purpose of this review and summarized the most recent findings regarding the accuracy of diagnostic methods, pathophysiology, and the prevalence of adenomyosis and optimal strategies for the treatment of infertile women with adenomyosis. Conclusions: Adenomyosis is a common gynecological disorder, affecting women of reproductive age. It negatively affects in vitro fertilization, pregnancy and the live birth rate, as well as increases the risk of miscarriage. With the advent of non-invasive diagnoses with MRI and TVUS, the role of adenomyosis in infertility has been better recognized. Overall, more randomized controlled trials (RCTs) are needed to provide strong data on the accuracy of diagnostic methods, the pathophysiology and the prevalence of adenomyosis, the fertility outcomes of patients and the optimal strategy for the treatment.
Disciplines :
Reproductive medicine (gynecology, andrology, obstetrics)
Author, co-author :
Pados, George;  1st Department of Obstetrics and Gynaecology, Papageorgiou General Hospital, School of Medicine, Aristotle University of Thessaloniki, 54643 Thessaloniki, Greece
Gordts, Stephan ;  Life Expert Centre, 3000 Leuven, Belgium
Sorrentino, Felice ;  Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, 71121 Foggia, Italy
Nisolle, Michelle ;  Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique
Nappi, Luigi;  Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, 71121 Foggia, Italy
Daniilidis, Angelos ;  1st Department of Obstetrics and Gynaecology, Papageorgiou General Hospital, School of Medicine, Aristotle University of Thessaloniki, 54643 Thessaloniki, Greece
Language :
English
Title :
Adenomyosis and Infertility: A Literature Review.
Publication date :
26 August 2023
Journal title :
Medicina
ISSN :
1010-660X
eISSN :
1648-9144
Publisher :
Multidisciplinary Digital Publishing Institute (MDPI), Switzerland
Volume :
59
Issue :
9
Pages :
1551
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 25 October 2023

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