age; epidemiology; kidney transplantation; patient characteristics; primary renal disease; sex
Abstract :
[en] BACKGROUND: The aim of this study was to provide an overview of age, sex and primary renal disease (PRD) distribution among first kidney transplant recipients across Europe. METHOD: The European Renal Association (ERA) Registry database was used to obtain data on patients aged 20 years or older receiving their first kidney transplant between 2010 and 2019 from 12 European countries. The numbers and percentages of recipients in each age, sex and PRD group were calculated by country, donor type and year. RESULTS: In total, 99 543 adults received a first kidney transplant. Overall, 23% of the recipients were 65 years or older, 36% were female and 21% had glomerulonephritis and 15% diabetes mellitus as PRD. Compared with deceased donor kidney transplant recipients, living donor kidney transplant recipients were less often 65 years or older (13% versus 26%), more often had glomerulonephritis (25% versus 20%) and less often diabetes mellitus (8% versus 17%) as PRD. We found large international differences, which were most prominent for age and PRD and less prominent for sex. Over time, the largest change in recipient characteristics was observed for the percentage of recipients aged 65 years or older, increasing from 18% in 2010 to 28% in 2019 for all countries combined with a similar trend in most countries. CONCLUSION: We observed large differences for age and PRD distribution between recipients of living and deceased donor kidneys and between European countries. Over time, the percentage of older first kidney transplant recipients increased.
Disciplines :
Urology & nephrology
Author, co-author :
Boenink, Rianne; ERA Registry, Department of Medical Informatics, Amsterdam UMC location AMC, University of Amsterdam, Amsterdam, The Netherlands. ; Amsterdam Public Health, Quality of Care and Ageing & Later Life, Amsterdam, The Netherlands.
Kramer, Anneke ; ERA Registry, Department of Medical Informatics, Amsterdam UMC location AMC, University of Amsterdam, Amsterdam, The Netherlands. ; Amsterdam Public Health, Quality of Care and Ageing & Later Life, Amsterdam, The Netherlands.
Masoud, Sherry; UK Renal Registry, UK Kidney Association, Bristol, UK. ; DPMCN, School of Medicine, Cardiff University, UK. ; Renal Medicine & Transplantation, North Bristol NHS Trust, UK.
Rodríguez-Benot, Alberto; Kidney and Pancreas Transplantation Unit, Nephrology Dept University Hospital Reina Sofia, Cordoba, Spain. ; Sistema de Información de la Coordinación Autonómica de Trasplantes de Andalucía (SICATA), Spain.
Helve, Jaakko; Finnish Registry for Kidney Diseases, Helsinki, Finland. ; Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Bistrup, Claus; Department of Nephrology, Odense University Hospital, Odense, Denmark.
Segelmark, Mårten M ; Department of Clinical Sciences, Lund University, Lund, Sweden. ; Department of Endocrinology, Nephrology and Rheumatology, Skane University Hospital, Lund, Sweden.
Rodríguez Arévalo, Olga L; Registry of Renal Patients of the Valencian Community, General Directorate of Public Health and Addictions, Ministry of Universal Health and Public Health, Valencia, Spain. ; Health and Well-being Technologies Program, Polytechnic University of Valencia, Valencia, Spain.
Kerschbaum, Julia ; Austrian Dialysis and Transplant Registry, Department of Internal Medicine IV - Nephrology and Hypertension, Medical University Innsbruck, Innsbruck, Austria.
de Vries, Aiko P J ; Department of Medicine, Division of Nephrology, Leiden Transplant Center, Leiden University Medical Center and Leiden University, Leiden, The Netherlands.
Lundgren, Torbjörn; Division of Transplantation Surgery, CLINTEC, Karolinska Institute, Stockholm, Sweden.
Bell, Samira ; Scottish Renal Registry, Meridian Court, Glasgow, UK. ; Division of Population Health and Genomics, University of Dundee, Dundee, UK.
Crespo, Marta; Department of Nephrology, Hospital del Mar, Barcelona, Spain. ; Institut Mar d'Investigacions Médiques, Barcelona, Spain.
Sørensen, Søren S; Department of Nephrology P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.
Ferraro, Pietro Manuel ; U.O.S. Terapia Conservativa della Malattia Renale Cronica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. ; Università Cattolica del Sacro Cuore, Rome, Italy.
Arnol, Miha; Department of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
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Weekers, Laurent ; Centre Hospitalier Universitaire de Liège - CHU > > Service de néphrologie ; French-Belgian ESRD Registry (GNFB), Brussels, Belgium.
Reisæter, Anna Varberg; Department of Transplantation Medicine, Oslo University hospital, Rikshospitalet, Norway.
Rebić, Damir; Clinic for Nephrology, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
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Jager, Kitty J ; ERA Registry, Department of Medical Informatics, Amsterdam UMC location AMC, University of Amsterdam, Amsterdam, The Netherlands. ; Amsterdam Public Health, Quality of Care and Ageing & Later Life, Amsterdam, The Netherlands.
Stel, Vianda S; ERA Registry, Department of Medical Informatics, Amsterdam UMC location AMC, University of Amsterdam, Amsterdam, The Netherlands. ; Amsterdam Public Health, Quality of Care and Ageing & Later Life, Amsterdam, The Netherlands.
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