HRQoL; Psychometric properties; Quality of life; Sarcopenia; Validation; Geriatrics and Gerontology; Aging
Abstract :
[en] Patient perspectives are now widely recognized as a key element in the evaluation of health interventions. Therefore, the provision of specific and validated Patient Reported Outcome Measures that emphasize the lived experience of patients suffering from specific diseases is very important. In the field of sarcopenia, the only validated specific health-related quality of life (HRQoL) instrument available is the Sarcopenia Quality of Life questionnaire (SarQoL). This self-administrated HRQoL questionnaire, developed in 2015, consists of 55 items arranged into 22 questions and has currently been translated into 35 languages. Nineteen validation studies performed on SarQoL have consensually confirmed the capacity of SarQoL to detect difference in HRQoL between older people with and without sarcopenia, its reliability and its validity. Two further observational studies have also indicated its responsiveness to change. A short form SarQoL, including only 14 items has further been developed and validated to reduce the potential burden of administration. Research on the psychometric properties of SarQoL questionnaire is still encouraged as the responsiveness to change of SarQoL has not yet been measured in the context of interventional studies, as limited prospective data currently exist and as there is still not cut-off score to define a low HRQoL. In addition, SarQoL has mainly been used in community-dwelling older individuals with sarcopenia and would benefit to be studied in other types of populations. This review aims to provide to researchers, clinicians, regulators, pharmaceutical industries and other stakeholders a clear summary of comprehensive evidence on the SarQoL questionnaire published up to January 2023Query.
Disciplines :
Public health, health care sciences & services
Author, co-author :
Beaudart, Charlotte ; Division of Public Health, Epidemiology and Health Economics, WHO Collaborating Center for Public Health Aspects of Musculo-Skeletal Health and Ageing, University of Liège, Liège, Belgium. c.beaudart@uliege.be
Reginster, Jean-Yves ; Université de Liège - ULiège > Département des sciences de la santé publique
Amuthavalli Thiyagarajan, Jotheeswaran; Department of Ageing and Life Course, WHO, Geneve, Switzerland
Bautmans, Ivan; Frailty in Ageing Research Department, Vrije Universiteit Brussel, Brussels, Belgium
Bauer, Jürgen; Center for Geriatric Medicine and Network Aging Research (NAR), Heidelberg University, Heidelberg, Germany
Burlet, Nansa ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Cesari, Matteo; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy ; Geriatric Unit, IRCCS Istituti Clinici Scientifici Maugeri, Milan, Italy
Cherubini, Antonio; Geriatria, Accettazione geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy
Cooper, Cyrus; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK
Cruz-Jentoft, Alfonso J; Servicio de Geriatría. Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain
Dawson-Hughes, Bess; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
Fielding, Roger A; Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, USA
Harvey, Nicholas C; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK ; NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK
Montero-Errasquin, Beatriz; Servicio de Geriatría. Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain
Concepción, Prieto Yerro María; Agencia Española de Medicamentos y Productos Sanitarios, Madrid, Spain
Rolland, Yves; Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, CERPOP UMR 1295, University of Toulouse III, Inserm, Toulouse, France
Rizzoli, René; Service of Bone Diseases, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland
Visser, Marjolein; Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam and the Amsterdam Public Health Research Institute, Amsterdam, The Netherlands
Bruyère, Olivier ; Division of Public Health, Epidemiology and Health Economics, WHO Collaborating Center for Public Health Aspects of Musculo-Skeletal Health and Ageing, University of Liège, Liège, Belgium
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