Active Pharmaceutical Ingredient; Automation; Biobased platforms; Flow chemistry; Chemistry (miscellaneous); Fluid Flow and Transfer Processes; Organic Chemistry
Abstract :
[en] Biomass is a renewable, almost infinite reservoir of a large diversity of highly functionalized chemicals. The conversion of biomass toward biobased platform molecules through biorefineries generally still lacks economic viability. Profitability could be enhanced through the development of new market opportunities for these biobased platform chemicals. The fine chemical industry, and more specifically the manufacturing of pharmaceuticals is one of the sectors bearing significant potential for these biobased building blocks to rapidly emerge and make a difference. There are, however, still many challenges to be dealt with before this market can thrive. Continuous flow technology and its integration for the upgrading of biobased platform molecules for the manufacturing of pharmaceuticals is foreseen as a game-changer. This perspective reflects on the main challenges relative to chemical, process, regulatory and supply chain-related burdens still to be addressed. The implementation of integrated continuous flow processes and their automation into modular units will help for tackling with these challenges.
Disciplines :
Chemistry
Author, co-author :
Kaisin, Geoffroy ; Université de Liège - ULiège > Département de chimie (sciences) > Center for Integrated Technology and Organic Synthesis ; SynLock SRL, Rue de la Vieille Sambre 153, B-5190 Jemeppe-sur-Sambre, Belgium
Bovy, Loïc ; Université de Liège - ULiège > Molecular Systems (MolSys)
Joyard, Yoann; SynLock SRL, Rue de la Vieille Sambre 153, B-5190 Jemeppe-sur-Sambre, Belgium
Maindron, Nicolas; SynLock SRL, Rue de la Vieille Sambre 153, B-5190 Jemeppe-sur-Sambre, Belgium
Tadino, Vincent; SynLock SRL, Rue de la Vieille Sambre 153, B-5190 Jemeppe-sur-Sambre, Belgium
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