Benefits of microsampling and microextraction for metabolomics studies

Hemmati, Maryam; Nix, Cindy; Crommen, Jacques; Servais, Anne-Catherine; Fillet, Marianne

doi:10.1016/j.trac.2020.115899

Request a copy

Article (Scientific journals)

Benefits of microsampling and microextraction for metabolomics studies

Hemmati, Maryam; Nix, Cindy; Crommen, Jacques et al.

2020 • In TrAC: Trends in Analytical Chemistry, 127, p. 115899

Peer Reviewed verified by ORBi

Permalink
https://hdl.handle.net/2268/302381

DOI
10.1016/j.trac.2020.115899

Files (1)Send to Details Statistics Bibliography Similar publications

Files

Full Text

1-s2.0-S016599362030128X-main-1.pdf

Publisher postprint (793.4 kB)

Request a copy

All documents in ORBi are protected by a user license.

Send to

RIS BibTex APA Chicago Permalink X Linkedin

Details

Keywords :

Metabolomics; Microextraction; Microsampling; Micro-extraction procedures

Abstract :

[en] The present review deals with the recent developments in metabolome analysis to improve the diagnosis of diseases and the identification of biomarkers. A particular focus has been put on the application of the non-invasive and up-to-date microsampling and microextraction procedures for the targeted/untargeted metabolome analysis from low volume of samples. These approaches aim to enhance sensitivity for the study of highly bioactive, short-lived, and low-abundant metabolites from complex matrices, especially when access to high sample volumes is not possible. The main strengths and weaknesses of those modern approaches as well as robust solutions to meet the undeniable challenges in metabolomics field are also presented. Moreover, some attractive alternatives for the better extraction of hydrophilic metabolites are discussed. Besides, information are given related to method validation results (such as recovery, matrix effect, detection limit, reproducibility, stability, etc.) as well as perspectives of these modern procedures in the context of diseases understanding, diagnosis, and follow up.

Disciplines :

Pharmacy, pharmacology & toxicology

Author, co-author :

Hemmati, Maryam ; Université de Liège - ULiège > Département de pharmacie > Analyse des médicaments

Nix, Cindy ; Université de Liège - ULiège > Département de pharmacie > Analyse des médicaments

Crommen, Jacques ; Université de Liège - ULiège > Département de pharmacie

Servais, Anne-Catherine ; Université de Liège - ULiège > Département de pharmacie > Analyse des médicaments

Fillet, Marianne ; Université de Liège - ULiège > Département de pharmacie > Analyse des médicaments

Language :

English

Title :

Benefits of microsampling and microextraction for metabolomics studies

Publication date :

June 2020

Journal title :

TrAC: Trends in Analytical Chemistry

ISSN :

0165-9936

eISSN :

1879-3142

Publisher :

Elsevier B.V.

Volume :

127

Pages :

115899

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://api.elsevier.com/content/article/PII:S016599362030128X?httpAccept=text/xml

Funders :

F.R.S.-FNRS - Fund for Scientific Research [BE]
Fonds Léon Fredericq [BE]

Funding text :

Authors appreciate the Belgian National Fund for Scientific Research and the Fonds Léon Fredericq for financial support.

Available on ORBi :

since 08 May 2023

Statistics

Number of views

26 (2 by ULiège)

Number of downloads

1 (1 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

Bibliography

Clish, C.B., Metabolomics: an emerging but powerful tool for precision medicine. Mol. Case Stud., 1, 2015, a000588.
Wishart, D.S., Feunang, Y.D., Marcu, A., Guo, A.C., Liang, K., Vázquez-Fresno, R., Sajed, T., Johnson, D., Li, C., Karu, N., HMDB 4.0: the human metabolome database for 2018. Nucleic Acids Res. 46 (2017), D608–D617.
Roberts, L.D., Souza, A.L., Gerszten, R.E., Clish, C.B., Targeted metabolomics. Curr. Protoc. Mol. Biol. 98 (2012), 30–32 31-32.30.32. 24.
Winter, G., Krömer, J.O., Fluxomics – connecting ‘omics analysis and phenotypes. Environ. Microbiol., 15(7), 1916, 1901.
Vuckovic, D., Current trends and challenges in sample preparation for global metabolomics using liquid chromatography–mass spectrometry. Anal. Bioanal. Chem. 403 (2012), 1523–1548.
Gong, Z.-G., Hu, J., Wu, X., Xu, Y.-J., The recent developments in sample preparation for mass spectrometry-based metabolomics. Crit. Rev. Anal. Chem. 47 (2017), 325–331.
Nys, G., Kok, M.G.M., Servais, A.-C., Fillet, M., Beyond dried blood spot: current microsampling techniques in the context of biomedical applications. Trac. Trends Anal. Chem. 97 (2017), 326–332.
Hernandes, V.V., Barbas, C., Dudzik, D., A review of blood sample handling and pre-processing for metabolomics studies. Electrophoresis 38 (2017), 2232–2241.
Kok, M.G., Fillet, M., Volumetric absorptive microsampling: current advances and applications. J. Pharmaceut. Biomed. Anal. 147 (2018), 288–296.
Protti, M., Mandrioli, R., Mercolini, L., Tutorial: volumetric absorptive microsampling (VAMS). Anal. Chim. Acta 1046 (2019), 32–47.
Wang, Q., Sun, T., Cao, Y., Gao, P., Dong, J., Fang, Y., Fang, Z., Sun, X., Zhu, Z., A dried blood spot mass spectrometry metabolomic approach for rapid breast cancer detection. OncoTargets Ther., 9, 2016, 1389.
Petrick, L., Edmands, W., Schiffman, C., Grigoryan, H., Perttula, K., Yano, Y., Dudoit, S., Whitehead, T., Metayer, C., Rappaport, S., An untargeted metabolomics method for archived newborn dried blood spots in epidemiologic studies. Metabolomics, 13, 2017, 27.
Haijes, H.A., Willemsen, M., Van der Ham, M., Gerrits, J., Pras-Raves, M.L., Prinsen, H.C., Van Hasselt, P.M., Sain-van der Velden, D., Monique, G., Verhoeven-Duif, N.M., Direct infusion based metabolomics identifies metabolic disease in patients’ dried blood spots and plasma. Metabolites, 9, 2019, 12.
DiBattista, A., McIntosh, N., Lamoureux, M., Al-Dirbashi, O.Y., Chakraborty, P., Britz-McKibbin, P., Metabolic signatures of cystic fibrosis identified in dried blood spots for newborn screening without carrier identification. J. Proteome Res. 18 (2018), 841–854.
Volani, C., Caprioli, G., Calderisi, G., Sigurdsson, B.B., Rainer, J., Gentilini, I., Hicks, A.A., Pramstaller, P.P., Weiss, G., Smarason, S.V., Pre-analytic evaluation of volumetric absorptive microsampling and integration in a mass spectrometry-based metabolomics workflow. Anal. Bioanal. Chem. 409 (2017), 6263–6276.
Volani, C., Paglia, G., Smarason, S., Pramstaller, P., Demetz, E., Pfeifhofer-Obermair, C., Weiss, G., Metabolic signature of dietary iron overload in a mouse model. Cells, 7, 2018, 264.
Cala, M.P., Meesters, R.J., Comparative study on microsampling techniques in metabolic fingerprinting studies applying gas chromatography–MS analysis. Bioanalysis 9 (2017), 1329–1340.
de Sain-van der Velden, M.G.M., van der Ham, M., Gerrits, J., Prinsen, H.C.M.T., Willemsen, M., Pras-Raves, M.L., Jans, J.J., Verhoeven-Duif, N.M., Quantification of metabolites in dried blood spots by direct infusion high resolution mass spectrometry. Anal. Chim. Acta 979 (2017), 45–50.
Han, J., Higgins, R., Lim, M.D., Atkinson, K., Yang, J., Lin, K., Borchers, C.H., Isotope-labeling derivatization with 3-nitrophenylhydrazine for LC/multiple-reaction monitoring-mass-spectrometry-based quantitation of carnitines in dried blood spots. Anal. Chim. Acta 1037 (2018), 177–187.
Jacob, M., Malkawi, A., Albast, N., Al Bougha, S., Lopata, A., Dasouki, M., Rahman, A.M.A., A targeted metabolomics approach for clinical diagnosis of inborn errors of metabolism. Anal. Chim. Acta 1025 (2018), 141–153.
Kok, M.G.M., Nix, C., Nys, G., Fillet, M., Targeted metabolomics of whole blood using volumetric absorptive microsampling. Talanta 197 (2019), 49–58.
Causon, T.J., Hann, S., Review of sample preparation strategies for MS-based metabolomic studies in industrial biotechnology. Anal. Chim. Acta 938 (2016), 18–32.
Drouin, N., Rudaz, S., Schappler, J., Sample preparation for polar metabolites in bioanalysis. Analyst 143 (2018), 16–20.
Huang, S., Chen, G., Ye, N., Kou, X., Zhu, F., Shen, J., Ouyang, G., Solid-phase microextraction: an appealing alternative for the determination of endogenous substances-A review. Anal. Chim. Acta 1077 (2019), 67–86.
Jiang, R., Pawliszyn, J., Thin-film microextraction offers another geometry for solid-phase microextraction. Trac. Trends Anal. Chem. 39 (2012), 245–253.
Nozoe, T., Goda, S., Selyanchyn, R., Wang, T., Nakazawa, K., Hirano, T., Matsui, H., Lee, S.-W., In vitro detection of small molecule metabolites excreted from cancer cells using a Tenax TA thin-film microextraction device. J. Chromatogr. B 991 (2015), 99–107.
Vincent, B., Jennifer, I., Mark, M., Richard, S., Leslie, B., Mark, S., Janusz, P., In vivo tissue sampling using solid-phase microextraction for non-lethal exposome-wide association study of CYP1A1 induction in Catostomus commersonii. Environ. Res. 151 (2016), 216–223.
Bessonneau, V., Boyaci, E., Maciazek-Jurczyk, M., Pawliszyn, J., In vivo solid phase microextraction sampling of human saliva for non-invasive and on-site monitoring. Anal. Chim. Acta 856 (2015), 35–45.
Bongaerts, J., De Bundel, D., Mangelings, D., Smolders, I., Vander Heyden, Y., Van Eeckhaut, A., Sensitive targeted methods for brain metabolomic studies in microdialysis samples. J. Pharmaceut. Biomed. Anal. 161 (2018), 192–205.
Bojko, B., Reyes-Garcés, N., Bessonneau, V., Goryński, K., Mousavi, F., Souza Silva, E.A., Pawliszyn, J., Solid-phase microextraction in metabolomics. Trac. Trends Anal. Chem. 61 (2014), 168–180.
Zhang, Q.-H., Zhou, L.-D., Chen, H., Wang, C.-Z., Xia, Z.-N., Yuan, C.-S., Solid-phase microextraction technology for in vitro and in vivo metabolite analysis. Trac. Trends Anal. Chem. 80 (2016), 57–65.
Živković Semren, T., Brčić Karačonji, I., Safner, T., Brajenović, N., Tariba Lovaković, B., Pizent, A., Gas chromatographic-mass spectrometric analysis of urinary volatile organic metabolites: optimization of the HS-SPME procedure and sample storage conditions. Talanta 176 (2018), 537–543.
Yu, L.-Q., Wang, L.-Y., Su, F.-H., Hao, P.-Y., Wang, H., Lv, Y.-K., A gate-opening controlled metal-organic framework for selective solid-phase microextraction of aldehydes from exhaled breath of lung cancer patients. Microchimica Acta, 185, 2018, 307.
Cavaco, C., Pereira, J.A., Taunk, K., Taware, R., Rapole, S., Nagarajaram, H., Câmara, J.S., Screening of salivary volatiles for putative breast cancer discrimination: an exploratory study involving geographically distant populations. Anal. Bioanal. Chem. 410 (2018), 4459–4468.
Monteiro, M., Moreira, N., Pinto, J., Pires-Luís, A.S., Henrique, R., Jerónimo, C., Bastos, M.d.L., Gil, A.M., Carvalho, M., Guedes de Pinho, P., GC-MS metabolomics-based approach for the identification of a potential VOC-biomarker panel in the urine of renal cell carcinoma patients. J. Cell Mol. Med. 21 (2017), 2092–2105.
Opitz, P., Herbarth, O., The volatilome–investigation of volatile organic metabolites (VOM) as potential tumor markers in patients with head and neck squamous cell carcinoma (HNSCC). J. Otolaryngol. Head Neck Surg., 47, 2018, 42.
Taunk, K., Taware, R., More, T.H., Porto-Figueira, P., Pereira, J.A., Mohapatra, R., Soneji, D., Câmara, J.S., Nagarajaram, H., Rapole, S., A non-invasive approach to explore the discriminatory potential of the urinary volatilome of invasive ductal carcinoma of the breast. RSC Adv. 8 (2018), 25040–25050.
Hough, R., Archer, D., Probert, C., A comparison of sample preparation methods for extracting volatile organic compounds (VOCs) from equine faeces using HS-SPME. Metabolomics, 14, 2018, 19.
Roszkowska, A., Yu, M., Bessonneau, V., Bragg, L., Servos, M., Pawliszyn, J., Tissue storage affects lipidome profiling in comparison to in vivo microsampling approach. Sci. Rep., 8, 2018, 6980.
Deng, J., Li, W., Yang, Q., Liu, Y., Fang, L., Guo, Y., Guo, P., Lin, L., Yang, Y., Luan, T., Biocompatible surface-coated probe for in vivo, in situ, and microscale lipidomics of small biological organisms and cells using mass spectrometry. Anal. Chem. 90 (2018), 6936–6944.
Roszkowska, A., Yu, M., Bessonneau, V., Bragg, L., Servos, M., Pawliszyn, J., Metabolome profiling of fish muscle tissue exposed to benzo [a] pyrene using in vivo solid-phase microextraction. Environ. Sci. Technol. Lett. 5 (2018), 431–435.
Bessonneau, V., Ings, J., McMaster, M., Smith, R., Bragg, L., Servos, M., Pawliszyn, J., In vivo microsampling to capture the elusive exposome. Sci. Rep., 7, 2017, 44038.
Reyes-Garcés, N., Diwan, M., Boyacı, E., Gómez-Ríos, G.A., Bojko, B., Nobrega, J.N., Bambico, F.R., Hamani, C., Pawliszyn, J., In vivo brain sampling using a microextraction probe reveals metabolic changes in rodents after deep brain stimulation. Anal. Chem. 91 (2019), 9875–9884.
Vasiljevic, T., Singh, V., Pawliszyn, J., Miniaturized SPME tips directly coupled to mass spectrometry for targeted determination and untargeted profiling of small samples. Talanta 199 (2019), 689–697.
Reyes-Garcés, N., Gionfriddo, E., Recent developments and applications of solid phase microextraction as a sample preparation approach for mass-spectrometry-based metabolomics and lipidomics. Trac. Trends Anal. Chem., 2019.
Belinato, J.R., Dias, F.F., Caliman, J.D., Augusto, F., Hantao, L.W., Opportunities for green microextractions in comprehensive two-dimensional gas chromatography/mass spectrometry-based metabolomics–A review. Anal. Chim. Acta 1040 (2018), 1–18.
Hu, S., Chen, X., Wang, R.-q., Yang, L., Bai, X.-h., Natural product applications of liquid-phase microextraction. Trac. Trends Anal. Chem. 113 (2019), 340–350.
Campillo, N., Viñas, P., Marín, J., Hernández-Córdoba, M., Glyoxal and methylglyoxal determination in urine by surfactant-assisted dispersive liquid–liquid microextraction and LC. Bioanalysis 9 (2017), 369–379.
Malaei, R., Ramezani, A.M., Absalan, G., Analysis of malondialdehyde in human plasma samples through derivatization with 2,4-dinitrophenylhydrazine by ultrasound-assisted dispersive liquid–liquid microextraction-GC-FID approach. J. Chromatogr. B 1089 (2018), 60–69.
Huang, Y., Huang, X., Huang, L., Liu, Q., Lei, Y., Yang, L., Huang, L., Three-phase solvent bar liquid-phase microextraction combined with high-performance liquid chromatography to determine sarcosine in human urine. J. Separ. Sci. 41 (2018), 3121–3128.
Zhao, X.-E., He, Y., Yan, P., Wei, N., Wang, R., Sun, J., Zheng, L., Zhu, S., You, J., Sensitive and accurate determination of neurotransmitters from in vivo rat brain microdialysate of Parkinson's disease using in situ ultrasound-assisted derivatization dispersive liquid–liquid microextraction by UHPLC-MS/MS. RSC Adv. 6 (2016), 108635–108644.
Wei, N., Zhao, X.-E., Zhu, S., He, Y., Zheng, L., Chen, G., You, J., Liu, S., Liu, Z., Determination of dopamine, serotonin, biosynthesis precursors and metabolites in rat brain microdialysates by ultrasonic-assisted in situ derivatization–dispersive liquid–liquid microextraction coupled with UHPLC-MS/MS. Talanta 161 (2016), 253–264.
Drouin, N., Rudaz, S., Schappler, J., New supported liquid membrane for electromembrane extraction of polar basic endogenous metabolites. J. Pharmaceut. Biomed. Anal. 159 (2018), 53–59.
Rye, T.K., Fuchs, D., Pedersen-Bjergaard, S., Petersen, N.J., Direct coupling of electromembrane extraction to mass spectrometry-Advancing the probe functionality toward measurements of zwitterionic drug metabolites. Anal. Chim. Acta 983 (2017), 121–129.
Pedersen-Bjergaard, S., Electromembrane extraction-looking into the future. 411, 2019, 1687–1693.
Ask, K.S., Lid, M., Øiestad, E.L., Pedersen-Bjergaard, S., Gjelstad, A., Liquid-phase microextraction in 96-well plates - calibration and accurate quantification of pharmaceuticals in human plasma samples. J. Chromatogr. A 1602 (2019), 117–123.