Article (Scientific journals)
Editor's Note: EGFR Activation and Signaling in Cancer Cells Are Enhanced by the Membrane-Bound Metalloprotease MT4-MMP.
PAYE, Alexandra; Truong, Alice; Yip, Cassandre et al.
2022In Cancer Research, 82 (4), p. 734
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Keywords :
Cancer Research; Oncology
Abstract :
[en] The editors are publishing this note to alert readers to concerns about this article (1). In Fig. 2, the actin loading control bands for cyclin D1 and cyclin D2 are identical-the authors clarified that the Western blots for cyclin D1 and cyclin D2 were performed on the same samples, however, this was not indicated in the figure legend. Additionally, in Fig. 6C, the p-EGFR bands in MDA-MB-231 cells showing stimulation by TGFa treatment are identical to the p-EGFR bands showing stimulation by EGF treatment. In the original submission of this manuscript, a correct version of this figure was used to show both TGFa and EGF could stimulate p-EGFR in control vector (CTR)- and MT4-MMP-expressing (MT4) MDA-MB-231 cells, but these panels were mistakenly duplicated in the revised and final versions of the manuscript.
Disciplines :
Oncology
Author, co-author :
PAYE, Alexandra ;  Centre Hospitalier Universitaire de Liège - CHU > > Institut d'oncologie
Truong, Alice ;  Université de Liège - ULiège > Département des sciences cliniques > Labo de biologie des tumeurs et du développement
Yip, Cassandre
Cimino, Jonathan ;  Université de Liège - ULiège > Département des sciences cliniques
Blacher, Silvia ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie cellulaire et moléculaire
Munaut, Carine  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques
Cataldo, Didier  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de pneumologie - allergologie
Foidart, Jean Michel
Maquoi, Erik  ;  Université de Liège - ULiège > Département des sciences cliniques > Labo de biologie des tumeurs et du développement
Collignon, Joëlle  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service d'oncologie médicale
Delvenne, Philippe ;  Centre Hospitalier Universitaire de Liège - CHU > > Service d'anatomie et cytologie pathologiques
Jerusalem, Guy  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service d'oncologie médicale
Noël, Agnès ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie cellulaire et moléculaire
Sounni, Nor Eddine
More authors (4 more) Less
Language :
English
Title :
Editor's Note: EGFR Activation and Signaling in Cancer Cells Are Enhanced by the Membrane-Bound Metalloprotease MT4-MMP.
Publication date :
15 February 2022
Journal title :
Cancer Research
ISSN :
0008-5472
eISSN :
1538-7445
Publisher :
American Association for Cancer Research (AACR), United States
Volume :
82
Issue :
4
Pages :
734
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 19 March 2023

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