[en] AIM: To evaluate the adjunctive effects of a Streptococcus oralis KJ3, Streptococcus uberis KJ2 and Streptococcus rattus JH145 containing probiotic tablet after scaling and root planing (SRP). MATERIALS AND METHODS: Forty-eight periodontitis patients were included in this double-blind, placebo-controlled clinical trial. After root planing, patients used either a placebo or a probiotic tablet twice a day for 12 weeks. The pocket probing depth (primary outcome measure), bleeding on probing and relative attachment levels were measured at baseline, 12 and 24 weeks. At baseline, 4, 8, 12 and 24 weeks, microbiological sampling was performed and plaque and gingival indices were recorded. RESULTS: The primary and secondary outcome measures were significantly (p < 0.05) improved at the 12- and the 24-week evaluation in both groups. However, no significant inter-group differences could be detected at any time point, except from the % of sites with plaque that were significantly lower in the probiotic group than in the control group at the 24-week evaluation. In addition, at the 12-week time point, the salivary Prevotella intermedia counts were significantly lower in the probiotic group. CONCLUSIONS: No differences were detected when comparing the adjunctive use of a placebo or the investigated streptococci containing probiotic tablet after SRP. ClinicalTrials.gov Identifier: NCT02403960.
Disciplines :
Dentistry & oral medicine
Author, co-author :
Laleman, Isabelle ; Centre Hospitalier Universitaire de Liège - CHU > > Service de parodontologie, chirurgie bucco-dentaire et chirurgie implantaire ; Department of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals
Yilmaz, Eftal; Department of Periodontology, Faculty of Dentistry, Cukurova Univerisity, Adana,
Ozcelik, Onur; Department of Periodontology, Faculty of Dentistry, Cukurova Univerisity, Adana,
Haytac, Cenk; Department of Periodontology, Faculty of Dentistry, Cukurova Univerisity, Adana,
Pauwels, Martine; Department of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals
Herrero, Esteban R; Department of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals
Slomka, Vera; Department of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals
Quirynen, Marc; Department of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals
Alkaya, Bahar; Department of Periodontology, Faculty of Dentistry, Cukurova Univerisity, Adana,
Teughels, Wim; Department of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals
Language :
English
Title :
The effect of a streptococci containing probiotic in periodontal therapy: a randomized controlled trial.
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