[en] [en] PURPOSE OF REVIEW: Severe burn injury causes significant metabolic changes and demands that make nutritional support particularly important. Feeding the severe burn patient is a real challenge in regard to the specific needs and the clinical constraints. This review aims to challenge the existing recommendations in the light of the few recently published data on nutritional support in burn patients.
RECENT FINDINGS: Some key macro- and micro-nutrients have been recently studied in severe burn patients. Repletion, complementation or supplementation of omega-3 fatty acids, vitamin C, vitamin D, antioxidant micronutrients may be promising from a physiologic perspective, but evidence of benefits on hard outcomes is still weak due to the studies' design. On the contrary, the anticipated positive effects of glutamine on the time to discharge, mortality and bacteremias have been disproved in the largest randomized controlled trial investigating glutamine supplementation in burns. An individualized approach in term of nutrients quantity and quality may proof highly valuable and needs to be validated in adequate trials. The combination of nutrition and physical exercises is another studied strategy that could improve muscle outcomes.
SUMMARY: Due to the low number of clinical trials focused on severe burn injury, most often including limited number of patients, developing new evidence-based guidelines is challenging. More high-quality trials are needed to improve the existing recommendations in the very next future.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Rousseau, Anne-Françoise ; Centre Hospitalier Universitaire de Liège - CHU > > Service des soins intensifs
Pantet, Olivier; Intensive Care Department, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland
Heyland, Daren K; Clinical Evaluation Research Unit, Department of Critical Care Medicine, Queen's University, Kingston, ON, Canada
Language :
English
Title :
Nutrition after severe burn injury.
Publication date :
01 March 2023
Journal title :
Current Opinion in Clinical Nutrition and Metabolic Care
ISSN :
1363-1950
eISSN :
1473-6519
Publisher :
Ovid Technologies (Wolters Kluwer Health), England
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