Article (Scientific journals)
Factors associated with the efficacy and safety of endoscopic dilatation of symptomatic strictures in Crohn's disease: a retrospective cohort study.
DANDOY, Pierre; Louis, Edouard; Gast, Pierrette et al.
2022In Scandinavian Journal of Gastroenterology, p. 1 - 9
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Keywords :
Crohn’s disease; adult; colonoscopy; dilatation; endoscopic balloon dilatation; endoscopy; inflammatory bowel disease; stricture; therapy; Gastroenterology
Abstract :
[en] ("[en] OBJECTIVE: Endoscopic balloon dilatation (EBD) is a standard treatment for intestinal strictures in Crohn's disease (CD). No evidence-based guidelines exist regarding the balloon diameter or the balloon pressure to be used, with recent studies suggesting the use of a smaller diameter than classically used. We sought to analyze the factors associated with safety and efficacy of EBD in CD strictures, particularly looking at balloon diameter and dilatation pressure. METHODS: We conducted a monocentric retrospective study of patients who underwent EBD between 2005 and 2020. RESULTS: Our endoscopy department performed EBD in 94 CD patients during the considered period. The mean size of balloon dilatation was 16 mm (±2.5; including 21 patients with balloon <14 mm) and the mean dilatation pressure was 5.3 atm (±1.5). No perforation was observed. Over a median follow-up of 5.6 years, the probability of being operated was 5.4% at 1 year and 10.4% at 3 years. Smaller height (HR = 0.90, p = 0.022) and a higher BMI (HR = 1.23, p = 0.014) were associated with the risk of operation. The probability of being operated or redilated was 30.1% at 1 year and 52.5% at 3 years. No factor was significantly associated with this risk. The size of the balloon had no impact on outcomes. CONCLUSION: In this retrospective cohort, including a significant proportion of CD patients dilated with balloon <14 mm, no perforation was observed and the size of the balloon or the dilatation pressure had no impact on the risk of surgery or redilatation.","[en] ","")
Disciplines :
Gastroenterology & hepatology
Author, co-author :
DANDOY, Pierre  ;  Centre Hospitalier Universitaire de Liège - CHU > > Frais communs médecine - Pool assistants
Louis, Edouard  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de gastroentérologie, hépatologie, onco. digestive
Gast, Pierrette ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de gastroentérologie, hépatologie, onco. digestive
Poncin, Maxime ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de gastroentérologie, hépatologie, onco. digestive
Seidel, Laurence  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service des informations médico économiques (SIME)
Loly, Jean-Philippe  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de gastroentérologie, hépatologie, onco. digestive
Language :
English
Title :
Factors associated with the efficacy and safety of endoscopic dilatation of symptomatic strictures in Crohn's disease: a retrospective cohort study.
Publication date :
19 December 2022
Journal title :
Scandinavian Journal of Gastroenterology
ISSN :
0036-5521
eISSN :
1502-7708
Publisher :
Taylor and Francis Ltd., England
Pages :
1 - 9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 16 January 2023

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