cardiology; cardiovascular disease; clinical researchpractice; donors and donation: deceased; donors and donation: donation after circulatory death (DCD); ethics; ethics and public policy; heart transplantation; organ procurement; organ procurement and allocation; Immunology and Allergy; Transplantation; Pharmacology (medical)
Abstract :
[en] While euthanasia has been legalized in a growing number of countries, organ donation after euthanasia is only performed in Belgium, the Netherlands, Spain, and Canada. Moreover, the clinical practice of heart donation after euthanasia has never been reported before. We describe the first case of a heart donated after euthanasia, reconditioned with thoraco-abdominal normothermic regional perfusion, preserved using cold storage while being transported to a neighboring transplant center, and then successfully transplanted following a procurement warm ischemic time of 17 min. Heart donation after euthanasia using thoraco-abdominal normothermic regional perfusion is feasible, it could expand the heart donor pool and reduce waiting lists in countries where organ donation after euthanasia can be performed.
Disciplines :
Surgery Anesthesia & intensive care Cardiovascular & respiratory systems
Author, co-author :
Tchana-Sato, Vincent ; Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie cardio-vasculaire et thoracique
Hans, Grégory ; Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation
Brouckaert, Janne; Department of Cardiac Surgery, University Hospitals, Leuven, Belgium
Detry, Olivier ; Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie abdo, sénologique, endocrine et de transplantation
Van Cleemput, Johan; Department of Cardiology, University Hospitals, Leuven, Belgium
Rex, Steffen; Department of Anesthesiology, University Hospitals, Leuven, Belgium
Jaquet, Océane ; Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation
De Troy, Erwin; Department of Intensive Care Medicine, University Hospitals, Leuven, Belgium
Trung, Mai-Linh Nguyen; Department of Cardiology, CHU, Liege, Belgium
Ancion, Arnaud ; Centre Hospitalier Universitaire de Liège - CHU > > Service de cardiologie
Van den Eynde, Raf; Department of Anesthesiology, University Hospitals, Leuven, Belgium
Lievens, Isabelle ; Centre Hospitalier Universitaire de Liège - CHU > > Service de neurologie
Lagny, Marc Gilbert; Department of Cardiovascular Surgery, CHU, Liege, Belgium
DELBOUILLE, Marie-Hélène ; Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie abdo, sénologique, endocrine et de transplantation
DEFRAIGNE, Jean ; Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie cardio-vasculaire et thoracique
Ledoux, Didier ; Centre Hospitalier Universitaire de Liège - CHU > > Service des soins intensifs
Rega, Filip; Department of Cardiac Surgery, University Hospitals, Leuven, Belgium
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