Neuroendocrine regulation of female aggression

De Moura Oliveira, Vinicius Elias; Bakker, Julie

doi:10.3389/fendo.2022.957114

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Neuroendocrine regulation of female aggression

De Moura Oliveira, Vinicius Elias; Bakker, Julie

2022 • In Frontiers in Endocrinology, 13

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https://hdl.handle.net/2268/293934

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10.3389/fendo.2022.957114

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Endocrinology, Diabetes and Metabolism

Abstract :

[en] Classically the neurobiology of aggression has been studied exclusively in males. Thus, females have been considered mildly aggressive except during lactation. Interestingly, recent studies in rodents and humans have revealed that non-lactating females can show exacerbated and pathological aggression similarly to males. This review provides an overview of recent findings on the neuroendocrine mechanisms regulating aggressive behavior in females. In particular, the focus will be on novel rodent models of exaggerated aggression established in non-lactating females. Among the neuromodulatory systems influencing female aggression, special attention has been given to sex-steroids and sex-steroid-sensitive neuronal populations (i.e., the core nuclei of the neural pathway of aggression) as well as to the neuropeptides oxytocin and vasopressin which are major players in the regulation of social behaviors.

Disciplines :

Life sciences: Multidisciplinary, general & others
Anatomy (cytology, histology, embryology...) & physiology
Neurosciences & behavior
Animal psychology, ethology & psychobiology

Author, co-author :

De Moura Oliveira, Vinicius Elias ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie de la différenciation sexuelle du cerveau

Bakker, Julie ; Université de Liège - ULiège > GIGA > GIGA Neurosciences - Neuroendocrinology

Language :

English

Title :

Neuroendocrine regulation of female aggression

Publication date :

10 August 2022

Journal title :

Frontiers in Endocrinology

eISSN :

1664-2392

Publisher :

Frontiers Media SA

Volume :

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://www.frontiersin.org/articles/10.3389/fendo.2022.957114/full

Funders :

F.R.S.-FNRS - Fonds de la Recherche Scientifique

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since 22 August 2022

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