Article (Scientific journals)
Inflammation et cancer : une relation complexe à double sens.
Scheen, André; Noël, Agnès; Delvenne, Philippe et al.
2022In Revue Médicale de Liège, 77 (5-6), p. 354-360
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Keywords :
Humans; Inflammation/complications/drug therapy; Neoplasms/drug therapy; Tumor Microenvironment; Cancer; Immunity; Inflammation; Oncology; Tumour; Anti; inflammatory drugs
Abstract :
[en] The relationships between inflammation and cancer are known since the original work by Virchow in the 19th century and have been largely confirmed after-wards. An interesting question is what might be the primum movens. Numerous clinical observations have shown that a chronic inflammatory state, as that observed with some infections, toxic agents or dysimmune diseases, may be associated with the development of cancer later on. Besides, cancer is generally accompanied by an inflammatory microenvironment, with numerous cellular and humoral components, which promotes both tumorigenesis and the invasivity of the tumour. This article aims at defining the pathophysiology of this association, with a description of underlying mechanisms and mediators, and at determining possible therapeutic implications.
Disciplines :
Oncology
Author, co-author :
Scheen, André  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de diabétologie, nutrition, maladies métaboliques
Noël, Agnès ;  Université de Liège - ULiège > GIGA > GIGA Cancer
Delvenne, Philippe ;  Service d'Anatomopathologie, CHU Liège, Belgique.
Jerusalem, Guy  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service d'oncologie médicale
Language :
French
Title :
Inflammation et cancer : une relation complexe à double sens.
Alternative titles :
[en] Inflammation and cancer : a complex two-way relationship.
Publication date :
May 2022
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Be
Special issue title :
Inflammation et maladies inflammatoires chroniques
Volume :
77
Issue :
5-6
Pages :
354-360
Peer reviewed :
Editorial Reviewed verified by ORBi
Available on ORBi :
since 18 August 2022

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