Article (Scientific journals)
Common Bias and Challenges in Physical and Rehabilitation Medicine Research: How to Tackle Them
Thibaut, Aurore; Beaudart, Charlotte; Martens, Géraldine et al.
2022In Frontiers in rehabilitation sciences, 3, p. 873241
Peer reviewed


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Keywords :
General Earth and Planetary Sciences; General Environmental Science
Abstract :
[en] The importance of evidence-based medicine is crucial, especially in physical and rehabilitation medicine (PRM), where there is a need to conduct rigorous experimental protocols, as in any medical field. Currently, in clinical practice, therapeutic approaches are often based on empirical data rather than evidence-based medicine. However, the field of PRM faces several challenges that may complicate scientific research. In addition, there is often a lack of appropriate research training in educational programs. In this context, we aim to review the methodological challenges in PRM and provide clear examples for each of them as well as potential solutions when possible. This article will cover the following themes: (1) Choosing the right study design and conducting randomized and benchmarking controlled trials; (2). Selecting the appropriate controlled, placebo or sham condition and the issue of blinding in non-pharmacological trials; (3) The impact of populations' heterogeneity and multi-comorbidities; (4). The challenge of recruitment and adherence; (5). The importance of homogeneity and proper quantification of rehabilitative strategies; and (6). Ethical issues. We are convinced that teaching the basics of scientific research in PRM could help physicians and therapists to choose a treatment based on (novel) scientific evidence. It may also promote scientific research in PRM to develop novel and personalized rehabilitation strategies using rigorous methodologies and randomized or benchmarking controlled trials in order to improve patients' management.
Disciplines :
Orthopedics, rehabilitation & sports medicine
Author, co-author :
Thibaut, Aurore ;  Université de Liège - ULiège > Département des sciences cliniques
Beaudart, Charlotte ;  Université de Liège - ULiège > Département des sciences de la motricité
Martens, Géraldine  ;  Université de Liège - ULiège > Evaluation-Revalidation (EVAREVA)
Bornheim, Stephen ;  Université de Liège - ULiège > Département des sciences de la motricité > Kinésithérapie neurologique
KAUX, Jean-François  ;  Université de Liège - ULiège > Evaluation-Revalidation (EVAREVA) ; Centre Hospitalier Universitaire de Liège - CHU > > Service de médecine de l'appareil locomoteur ; Université de Liège - ULiège > Département des sciences de la motricité > Médecine physique, réadaptation et traumatologie du sport
Language :
Title :
Common Bias and Challenges in Physical and Rehabilitation Medicine Research: How to Tackle Them
Publication date :
June 2022
Journal title :
Frontiers in rehabilitation sciences
Publisher :
Frontiers Media SA
Special issue title :
Pursuing quality education in Physical and Rehabilitation Medicine
Volume :
Pages :
Peer reviewed :
Peer reviewed
Available on ORBi :
since 10 August 2022


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