Article (Scientific journals)
Anticoagulants oraux directs. Avancée thérapeutique de la décennie.
SPRYNGER, Muriel; LANCELLOTTI, Patrizio
2020In Revue Médicale de Liège, 75 (5-6), p. 310-315
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Keywords :
Anticoagulants; Administration, Oral; Anticoagulants/administration & dosage; Atrial Fibrillation; Humans; Venous Thromboembolism; Antagonists; Atrial fibrillation; Heparin; Venous thromboembolic disease; Vitamin K; Direct oral anticoagulants
Abstract :
[en] In the past decade atrial fibrillation (AF) and venous thromboembolic disease (VTE) treatment have been revolutionized by direct oral anticoagulants (DOACs). Compared to vitamin K antagonists, DOACs have interesting advantages : standardized dosages (no need for monitoring), fast action, short half-life, (no food interaction and lower risk of intracranial bleeding). In addition to VTE and AF, DOACs have specific indications : prevention of postorthopedic surgery VTE and more recently, prevention of cardiovascular events in patients with stable coronaropathy and/or peripheral artery disease. Nevertheless, DOACs must be handled with care according to dosage regimens, contra-indications, drug-drug interactions. Other anticoagulants are in the pipeline. What will their indications be ? Future will tell us.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
SPRYNGER, Muriel ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de cardiologie
LANCELLOTTI, Patrizio  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de cardiologie
Language :
French
Title :
Anticoagulants oraux directs. Avancée thérapeutique de la décennie.
Alternative titles :
[en] Direct oral anticoagulants : therapeutic breakthroughs over the past decade.
Publication date :
May 2020
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Be
Volume :
75
Issue :
5-6
Pages :
310-315
Peer reviewed :
Editorial Reviewed verified by ORBi
Available on ORBi :
since 24 June 2022

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