Article (Scientific journals)
Perineuronal nets in HVC and plasticity in male canary song
Cornez, Gilles; Valle, Shelley; Barros Dos Santos, Ednei et al.
2021In PLoS ONE, 16 (8), p. 0252560
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Keywords :
Multidisciplinary
Abstract :
[en] Songbirds learn their vocalizations during developmental sensitive periods of song memorization and sensorimotor learning. Some seasonal songbirds, called open-ended learners, recapitulate transitions from sensorimotor learning and song crystallization on a seasonal basis during adulthood. In adult male canaries, sensorimotor learning occurs each year in autumn and leads to modifications of the syllable repertoire during successive breeding seasons. We previously showed that perineuronal nets (PNN) expression in song control nuclei decreases during this sensorimotor learning period. Here we explored the causal link between PNN expression in adult canaries and song modification by enzymatically degrading PNN in HVC, a key song control system nucleus. Three independent experiments identified limited effects of the PNN degradation in HVC on the song structure of male canaries. They clearly establish that presence of PNN in HVC is not required to maintain general features of crystallized song. Some suggestion was collected that PNN are implicated in the stability of song repertoires but this evidence is too preliminary to draw firm conclusions and additional investigations should consider producing PNN degradations at specified time points of the seasonal cycle. It also remains possible that once song has been crystallized at the beginning of the first breeding season, PNN no longer play a key role in determining song structure; this could be tested by treatments with chondroitinase ABC at key steps in ontogeny. It would in this context be important to develop multiple stereotaxic procedures allowing the simultaneous bilateral degradation of PNN in several song control nuclei for extended periods.
Disciplines :
Zoology
Neurosciences & behavior
Author, co-author :
Cornez, Gilles ;  Université de Liège - ULiège > GIGA > GIGA Neurosciences - Neuroendocrinology
Valle, Shelley ;  Université de Liège - ULiège > GIGA > GIGA Neurosciences - Neuroendocrinology
Barros Dos Santos, Ednei ;  Université de Liège - ULiège > GIGA > GIGA Neurosciences - Neuroendocrinology
Chiver, Ioana ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques
Muller, Wendt;   Behavioural Ecology and Ecophysiology Lab, University of Antwerp, Antwerp, Belgium
Ball, Gregory;   Department of Psychology, University of Maryland, Maryland, College Park, United States of America
Cornil, Charlotte  ;  Université de Liège - ULiège > GIGA > GIGA Neurosciences - Neuroendocrinology
Balthazart, Jacques  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques
Language :
English
Title :
Perineuronal nets in HVC and plasticity in male canary song
Publication date :
27 August 2021
Journal title :
PLoS ONE
eISSN :
1932-6203
Publisher :
Public Library of Science (PLoS)
Volume :
16
Issue :
8
Pages :
e0252560
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
ULiège - Université de Liège [BE]
NINDS - National Institute of Neurological Disorders and Stroke [US-MD] [US-MD]
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