biofortification; crop; human health; metabolism; vitamins; Plant Science
Abstract :
[en] Vitamin deficiencies are major forms of micronutrient deficiencies, and are associated with huge economic losses as well as severe physical and intellectual damages to humans. Much evidence has demonstrated that biofortification plays an important role in combating vitamin deficiencies due to its economical and effective delivery of nutrients to populations in need. Biofortification enables food plants to be enriched with vitamins through conventional breeding and/or biotechnology. Here, we focus on the progress in the manipulation of the vitamin metabolism, an essential part of biofortification, by the genetic modification or by the marker-assisted selection to understand mechanisms underlying metabolic improvement in food plants. We also propose to integrate new breeding technologies with metabolic pathway modification to facilitate biofortification in food plants and, thereby, to benefit human health.
Jiang, Ling; Biotechnology Research Institute, Chinese Academy of Agricultural SciencesBeijing, China ; National Key Facility for Crop Gene Resources and Genetic ImprovementBeijing, China
Wang, Weixuan; Biotechnology Research Institute, Chinese Academy of Agricultural SciencesBeijing, China ; National Key Facility for Crop Gene Resources and Genetic ImprovementBeijing, China
Lian, Tong ; Université de Liège - ULiège > TERRA Research Centre ; Biotechnology Research Institute, Chinese Academy of Agricultural SciencesBeijing, China
Zhang, Chunyi; Biotechnology Research Institute, Chinese Academy of Agricultural SciencesBeijing, China ; National Key Facility for Crop Gene Resources and Genetic ImprovementBeijing, China
Language :
English
Title :
Manipulation of Metabolic Pathways to Develop Vitamin-Enriched Crops for Human Health.
This work was financially supported by the National Basic Research Program of China (grant no. 2013CB127003 to CZ), the Ministry of Science and Technology of China (2016YFD0100503 to LJ), and the National Natural Science Foundation of China (grant no. 31301398 to WW).We thank Dr. Lan Zhang and Ms. Ying Liu at Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, for valuable discussions.
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