Article (Scientific journals)
Prevalence of occult HCV infection in hemodialysis and kidney-transplanted patients: A systematic review
Dolatimehr, Fardin; Khosravi, Mohammad Hossein; Rezaee-Zavareh, Mohammad Saeid et al.
2017In Future Virology, 12 (5), p. 315 - 322
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Keywords :
kidney transplantation; occult hepatitis C; renal dialysis; Virology
Abstract :
[en] Aim: We performed a systematic review for determining the prevalence rate of occult HCV infection (OCI) among hemodialysis and kidney-transplanted (KT) patients. Methods: Electronic databases were searched with appropriate search strategies. We considered positive result for tests of HCV-RNA in peripheral blood mononuclear cell, ultracentrifuged serum or hepatocytes in the absence of HCV-RNA and anti-HCV antibody in patients' sera as the definition of OCI. Results: Two studies reported OCI prevalence rate of 0 and 2% among KT patients. Results of OCI prevalence rates among hemodialysis patients varied between 0 and 45% in ten different included studies showing a great heterogeneity. Conclusion: Although we still need more evidence to support our results, they suggest that checking OCI in hemodialysis or KT patients with unexplained signs of liver diseases may have some benefit.
Disciplines :
Gastroenterology & hepatology
Author, co-author :
Dolatimehr, Fardin;  Stud. Research Commitee, Baqiyatallah University of Medical Sciences, Tehran, Iran ; Baqiyatallah Research Center for Gastroenterology and Liver Diseases (BRCGL), Baqiyatallah University of Medical Sciences, Tehran, Iran ; Middle East Liver Diseases (MELD) Center, Tehran, Iran
Khosravi, Mohammad Hossein  ;  Université de Liège - ULiège > Faculté de Médecine > Doct. sc. méd. (paysage)
Rezaee-Zavareh, Mohammad Saeid;  Stud. Research Commitee, Baqiyatallah University of Medical Sciences, Tehran, Iran ; Baqiyatallah Research Center for Gastroenterology and Liver Diseases (BRCGL), Baqiyatallah University of Medical Sciences, Tehran, Iran ; Middle East Liver Diseases (MELD) Center, Tehran, Iran
Alavian, Seyed Moayed;  Baqiyatallah Research Center for Gastroenterology and Liver Diseases (BRCGL), Baqiyatallah University of Medical Sciences, Tehran, Iran ; Middle East Liver Diseases (MELD) Center, Tehran, Iran
Language :
English
Title :
Prevalence of occult HCV infection in hemodialysis and kidney-transplanted patients: A systematic review
Publication date :
May 2017
Journal title :
Future Virology
ISSN :
1746-0794
Publisher :
Future Medicine Ltd.
Volume :
12
Issue :
5
Pages :
315 - 322
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 21 May 2022

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