oncology; radiation therapy; head and neck cancer; split-course hypofractionated irradiation; hypofractionation; radiotherapy side-effects; mucositis; dysphagia; oncologie; radiothérapie oncologie; cancers de la tête et du cou; radiothérapie concentrée discontinue; hypofractionnement; effets secondaires de l'irradiation; mucite; dysphagie; GCSF; Filgrastim
Abstract :
[en] A possible benefit of GCSF was investigated among head and neck cancer patients receiving a split-course hypofractionated radiotherapy. Parameters taken in consideration of mucosal side-effects were grades 0 to 5 mucositis, grades 0 to 5 dysphagia and 3 degrees of global intolerance summing the two former items. GCSF was given for 6 consecutive days at mid- and end of treatment. All the mentioned criterias were significantly shifted towards better tolerance as compared to the untreated group.
Disciplines :
Oncology
Author, co-author :
Deneufbourg, Jean-Marie ; Université de Liège - ULiège > Département des sciences cliniques > Radiothérapie
Piret, Pascal ; Université de Liège - ULiège > Département des sciences cliniques > Radiothérapie
Bonniver, Fabienne; ULiège - Université de Liège > Département des sciences cliniques > Radiothérapie
Collette, Maryvonne; ULiège - Université de Liège > Département des sciences cliniques > Radiothérapie
Language :
English
Title :
Possible Role of Granulocyte Colony-stimulating Factor (Filgrastim) in the Management of Radiation Induced Oral Mucositis and Dysphagia
Publication date :
July 1996
Event name :
4th International Conference on Head and Neck Cancer
Event organizer :
Canadian Society of Head and Neck Surgeons American Society for Head and Neck Surgery
Event place :
Toronto, Canada
Event date :
28/7 - 1/8 1996
Event number :
4
Audience :
International
Main work title :
4th ICHNC Book of Abstracts TORONTO
Editor :
Shah, Jatin P.; Memorial Sloan Ca Ctr > Head and Neck Service > New-York NY USA
Johnson, Jonas T.; Eye and Ear Hospital > Pittsburgh PA USA
