Diversity of the Mechanisms of Resistance to Beta-Lactam Antibiotics

Frère, Jean-Marie; Joris, Bernard; Granier, B.; Matagne, André; Ackerman, Francine; Bourguignon-Bellefroid, C.

doi:10.1016/0923-2508(91)90084-N

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Diversity of the Mechanisms of Resistance to Beta-Lactam Antibiotics

Frère, Jean-Marie; Joris, Bernard; Granier, B. et al.

1991 • In Research in Microbiology, 142 (6, Jul-Aug), p. 705-10

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https://hdl.handle.net/2268/28922

DOI
10.1016/0923-2508(91)90084-N

PubMed
1961980

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Abstract :

[en] The sensitivity of a bacterium to beta-lactam antibiotics depends upon the interplay between 3 independent factors: the sensitivity of the essential penicillin-binding enzyme(s), the quantity and properties of the beta-lactamase(s) and the diffusion barrier that the outer-membrane of Gram-negative bacteria can represent. Those three factors can be modified by mutations or by the horizontal transfer of genes or portions of genes.

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Frère, Jean-Marie ; Université de Liège - ULiège > Laboratoire d'Enzymologie, Centre d'Ingénierie des Protéines

Joris, Bernard ; Université de Liège - ULiège > Centre d'ingénierie des protéines

Granier, B.; Université de Liège - ULiège > Laboratoire d'Enzymologie, Centre d'Ingénierie des Protéines

Matagne, André ; Université de Liège - ULiège > Laboratoire d'Enzymologie, Centre d'Ingénierie des Protéines

Ackerman, Francine ; Centre Hospitalier Universitaire de Liège - CHU > Cardiologie

Bourguignon-Bellefroid, C.; Université de Liège - ULiège > Laboratoire d'Enzymologie, Centre d'Ingénierie des Protéines

Language :

English

Title :

Diversity of the Mechanisms of Resistance to Beta-Lactam Antibiotics

Publication date :

1991

Journal title :

Research in Microbiology

ISSN :

0923-2508

eISSN :

1769-7123

Publisher :

Elsevier, Netherlands

Volume :

142

Issue :

6, Jul-Aug

Pages :

705-10

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 23 November 2009

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Bibliography

Amicosante, Franceschini, Segatore, Oratore, Fattorini, Orefici, Van Beeumen, Frère (1990) Characterization of a β-lactamase produced in Myobacterium fortuitum D316. Biochem. J. 271:729-734.
Barthélemy, Péduzzi, Yaghlane, Labia (1988) Single amino acid substitution between SHV-1 β-lactamase and cefotaxime-hydrolysing SHV-2 enzyme. FEBS Letters 231:217-220.
Brannigan, Tirodimos, Zhang, Dowson, Spratt (1990) Insertion of an extra amino acid is the main cause of the low affinity of penicillin-binding protein-2 in penicillin-resistant strains of Neisseria gonorrhoeae. Mol. Microbiol. 4:913-919.
Chase, Reynolds (1981) The cell wall as a permeability barrier to beta-lactam antibiotics in Bacillus megaterium. FEMS Microbiol. Letters 10:285-289.
Fontana, Cerini, Longoni, Grossato, Canepari (1983) Identification of a streptococcal penicillin-binding protein that reacts very slowly with penicillin. J. Bact. 155:1343-1350.
Frère (1989) Quantitative y relationship between sensitivity to beta-lactam antibiotics and beta-lactamase production in Gram-negative bacteria. — 1. Steady-state treatment. Biochem. Pharmacol. 38:1415-1426.
Frère, Duez, Ghuysen, Vandekerckhove (1976) Occurrence of a serine residue in the penicillin-binding site of the exocellular DD-carboxy-peptidase-transpeptidase from Streptomyces R61. FEBS Letters 70:257-260.
Frère, Ghuysen, Degelaen, Loffet, Perkins (1975) Fragmentation of benzylpenicillin after interaction with the exocellular DD-carboxy-peptidase-transpeptidases of Streptomyces R61 et R39. Nature 258:168-170.
Frère, Joris (1985) Penicillin-sensitive enzymes in peptidoglycan biosynthesis. CRC Crit. Rev. Microbiol. 1:299-396.
Frère, Joris (1988) Beta-lactamases as the main resistance factor to penicillin-related antibiotics. Ann. Biol. Clin. 46:151-156.
Frère, Joris, Crine, Martin (1989) Quantitative relationship between sensitivity to beta-lactam antibiotics anbeta-lactamase production in Gram-negative bacteria. — II. Non-steady-state treatment and progress curves. Biochem. Pharmacol. 38:1427-1433.
Galleni, Amicosante, Frère (1988) A survey of the kinetic parameters of class C β-lactamases. — II. Cephalosporins and other β-lactam compounds. Biochem. J. 255:123-129.
Galleni, Frère (1988) A survey of the kinetic parameters of class C β-lactamases. — I. Penicillins. Biochem. J. 255:119-122.
Hechler, Van Den Weghe, Martin, Frère (1989) Overproduced β-lactamase and the outer membrane barrier as resistance factors in Serratia marcescens highly resistant to β-lactamase stable β-lactam antibiotics. J. gen. Microbiol. 135:1275-1290.
Jacob, Joris, Dideberg, Dusart, Ghuysen, Frère (1990) Engineering a novel β-lactamase by a single point mutation. Protein Eng. 4:79-86.
Joris, Ghuysen, Dive, Renard, Dideberg, Charlier, Frère, Kelly, Boyington, Moews, Knox (1988) The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family. Biochem. J. 250:313-324.
Kelly, Dideberg, Charlier, Wéry, Libert, Moews, Knox, Duez, Fraipont, Joris, Dusart, Frère, Ghuysen (1986) On the origin of bacterial resistance to penicillin: comparison of a β-lactamase and a penicillin target. Science 231:1429-1431.
Leyh-Bouille, Nguyen-Distèche, Pirlot, Veithen, Bourguignon, Ghuysen (1986) Streptomyces K15 DD-peptidase-catalysed reactions with suicide beta-lactam carbonyl donors. Biochem. J. , [published erratum appears in Biochem. J., 15, 236(3): following 933]; 235:177-182.
Nicolas, Jarlier, Honoré, Philippon, Cole (1989) Molecular characterization of the gene encoding SHV-3 β-lactamase responsible for transferable cefotaxime resistance in clinical isolates of Klebsiella pneumoniae. Antimicrob. Agents a. Chemother. 33:2096-2100.
Nikaido (1985) Role of permeability barriers in resistance to beta-lactam antibiotics. Pharmacol. Ther. 27:197-231.
Nikaido, Normark (1987) Sensitivity of Escherichia coli to various β-lactams is determined by the interplay of outer membrane permeability and degradation by periplasmic β-lactamase: a quantitative predictive treatment. Mol. Microbiol. 1:29-36.
Sanders (1983) Novel resistance selected by the new expanded-spectrum cephalosporins: a concern. J. infect. Dis. 47:585-589.
Song, Wachi, Doi, Ishino, Matsuhashi (1987) Evolution of an inducible penicillin-target protein in methicillin-resistant S. aureus by gene fusion. FEBS Letters 221:167-171.
Sougakoff, Goussard, Gerbaud, Courvalin (1988) Plasmid-mediated resistance to third-generation cephalosporins caused by TEM-type penicillinase genes. Rev. infect. Dis. 10:879-884.
Sougakoff, Petit, Goussard, Sirot, Bure, Courvalin (1989) Characterization of the plasmid genes blaT-4 and blaT-5 which encode the broad spectrum β-lactamases TEM-4 and TEM-5 in Enterobacteriaceaea. Gene 783:339-348.
Spratt, Zhang, Jones, Hutchison, Brannigan (1990) Recruitment of a penicillin-binding protein gene from Neisseria flavescens during the emergence of penicillin resistance in Neisseria meningiditis. Proceedings of the National Academy of Sciences 86:8988-8992.
Spratt (1977) Properties of the penicillin-binding proteins of Escherichia coli K12. Europ. J. Biochem. 72:341-352.
Then, Anghern (1982) Trapping of non-hydrolysable cephalosporins in Enterobacter cloacae and Pseudomonas aeruginosa as a possible resistance mechanism. Antimicrob. Agents a. Chemother. 21:711-717.
Waley (1987) An explicit model for bacterial resistance: application to beta-lactam antibiotics. Microbiol. Sci. 4:143-146.
Zimmermann, Rosselet (1977) The function of the outer membrane of Escherichia coli as a permeability barrier to β-lactam antibiotics. Antimicrob. Agents a. Chemother. 12:368-372.