[en] In forensic science, the emission of odours from objects or biological matrices is exploited for different purposes. For example, the monitoring of odours via biological or analytical detectors is used in thanatochemistry, the chemistry of death. The analysis of decomposition odour can be explored to support the localization of a missing body, a scenario encountered in urban search and rescue operations. A better understanding of the formation and evolution of decomposition odour is also of high interest to human remains detection canine handlers to improve training practices and chose appropriate training aids. Next to thanatochemistry, many other types of evidence evaluation benefit from the characterization of the volatile profile including the analysis of fire debris, chemical threat agents, explosives, and drugs. From a chemical point of view, an odour represents a complex mixture of gaseous molecules and its characterization demands for a powerful analytical technique. Especailly, in non-targeted analysis, the separation power provided by one-dimensional (1D) gas chromatography (GC) can be surpassed. Thus, a better insight is usually achieved using a multidimensional technique, such as comprehensive two-dimensional gas chromatography (GC×GC). This chapter focuses on scientific articles published between 2015 and 2020 reporting on the use of GC×GC for odour characterization in the context of forensic science. The main points are decomposition odour, volatolomic applications for profiling of human scent and illegal trade goods such as wildlife parts. Furthermore, the investigation of volatile traces of drugs and ignitable liquids in the context of arson investigations is addressed in detail. For each section, the length is proportional to the number of publications from the literature review.
Disciplines :
Chemistry
Author, co-author :
Dubois, Lena ; Université de Liège - ULiège > Molecular Systems (MolSys)
O'Sullivan, Gwen; Department of Earth and Environmental Sciences, Mount Royal University, Calgary, Canada
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Bibliography
Margot, P., Forensic science on trial—what is the law of the land?. Aust. J. Forensic Sci. 43 (2011), 89–103, 10.1080/00450618.2011.555418.
Stefanuto, P.-H., Focant, J.-F., GC×GC-TOFMS, the Swiss knife for VOC mixtures analysis in soil forensic investigations. Kars, Henk, van den Eijkel, Lida, (eds.) Soil in Criminal and Environmental Forensics, 2016, Springer, 317–329.
DeGreeff, L.E., Weakley-Jones, B., Furton, K.G., Creation of training aids for human remains detection canines utilizing a non-contact, dynamic airflow volatile concentration technique. Forensic Sci. Int. 217 (2012), 32–38, 10.1016/j.forsciint.2011.09.023.
Schoon, G.A.A., The effect of the ageing of crime scene objects on the results of scent identification line-ups using trained dogs. Forensic Sci. Int. 147 (2005), 43–47, 10.1016/j.forsciint.2004.04.080.
Tomaszewski, T., Girdwoyn, P., Scent identification evidence in jurisdiction (drawing on the example of judicial practice in Poland). Forensic Sci. Int. 162 (2006), 191–195, 10.1016/j.forsciint.2006.06.017.
Boegelsack, N., Withey, J., O'Sullivan, G., McMartin, D., A critical examination of the relationship between wildfires and climate change with consideration of the human impact. J Environ Prot (Irvine, Calif) 09 (2018), 461–467, 10.4236/jep.2018.95028.
Balch, J.K., Bradley, B.A., Abatzoglou, J.T., et al. Human-started wildfires expand the fire niche across the United States. Proc. Natl. Acad. Sci. U. S. A. 114 (2017), 2946–2951, 10.1073/pnas.1617394114.
Martín-Alberca, C., Ortega-Ojeda, F.E., García-Ruiz, C., Analytical tools for the analysis of fire debris. A review: 2008-2015. Anal. Chim. Acta 928 (2016), 1–19, 10.1016/j.aca.2016.04.056.
Baerncopf, J., Hutches, K., A review of modern challenges in fire debris analysis. Forensic Sci. Int. 244 (2014), e12–e20, 10.1016/j.forsciint.2014.08.006.
Sampat, A., Lopatka, M., Sjerps, M., et al. Forensic potential of comprehensive two-dimensional gas chromatography. TrAC Trends Anal. Chem. 80 (2016), 345–363, 10.1016/j.trac.2015.10.011.
Gruber, B., Weggler, B.A., Jaramillo, R., et al. Comprehensive two-dimensional gas chromatography in forensic science: a critical review of recent trends. TrAC Trends Anal. Chem. 105 (2018), 292–301, 10.1016/J.TRAC.2018.05.017.
Dubois, L.M., Aczon, S., Focant, J.-F., Perrault, K.A., Translation of a one-dimensional to a comprehensive two-dimensional gas chromatography method with dual-channel detection for volatile organic compound measurement in forensic applications. Anal Chem, 2020, 10.1021/acs.analchem.0c01926.
Perrault, K.A., Stefanuto, P.-H., Stuart, B.H., et al. Detection of decomposition volatile organic compounds in soil following removal of remains from a surface deposition site. Forensic Sci. Med. Pathol. 11 (2015), 376–387, 10.1007/s12024-015-9693-5.
Rosier, E., Loix, S., Develter, W., et al. Time-dependent VOC-profile of decomposed human and animal remains in laboratory environment. Forensic Sci. Int. 266 (2016), 164–169, 10.1016/j.forsciint.2016.05.035.
Chilcote, B., Rust, L., Nizio, K.D., Forbes, S.L., Profiling the scent of weathered training aids for blood-detection dogs. Sci. Justice 58 (2018), 98–108, 10.1016/j.scijus.2017.11.006.
Verheggen, F., Perrault, K.A., Megido, R.C., et al. The odor of death: an overview of current knowledge on characterization and applications. Bioscience 67 (2017), 600–613, 10.1093/biosci/bix046.
Vass, A.A., Smith, R.R., Thompson, C.V., et al. Decompositional odor analysis database. J. Forensic Sci. 49 (2004), 1–10, 10.1520/JFS2003434.
Vass, A.A., Smith, R.R., Thompson, C.V., et al. Odor analysis of decomposing buried human remains. J. Forensic Sci. 53 (2008), 384–391, 10.1111/j.1556-4029.2008.00680.x.
Statheropoulos, M., Agapiou, A., Spiliopoulou, C., et al. Environmental aspects of VOCs evolved in the early stages of human decomposition. Sci. Total Environ. 385 (2007), 221–227, 10.1016/j.scitotenv.2007.07.003.
Statheropoulos, M., Spiliopoulou, C., Agapiou, A., A study of volatile organic compounds evolved from the decaying human body. Forensic Sci. Int. 153 (2005), 147–155, 10.1016/j.forsciint.2004.08.015.
Hoffman, E.M., Curran, A.M., Dulgerian, N., et al. Characterization of the volatile organic compounds present in the headspace of decomposing human remains. Forensic Sci. Int. 186 (2009), 6–13, 10.1016/j.forsciint.2008.12.022.
Dekeirsschieter, J., Verheggen, F.J., Gohy, M., et al. Cadaveric volatile organic compounds released by decaying pig carcasses (Sus domesticus L.) in different biotopes. Forensic Sci. Int. 189 (2009), 46–53, 10.1016/j.forsciint.2009.03.034.
Stadler, S., Stefanuto, P.-H., Brokl, M., et al. Characterization of volatile organic compounds from human analogue decomposition using thermal desorption coupled to comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Anal. Chem. 85 (2013), 998–1005, 10.1021/ac302614y.
Brasseur, C., Dekeirsschieter, J., Schotsmans, E.M.J., et al. Comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the forensic study of cadaveric volatile organic compounds released in soil by buried decaying pig carcasses. J. Chromatogr. A 1255 (2012), 163–170, 10.1016/j.chroma.2012.03.048.
Agapiou, A., Zorba, E., Mikedi, K., et al. Analysis of volatile organic compounds released from the decay of surrogate human models simulating victims of collapsed buildings by thermal desorption-comprehensive two-dimensional gas chromatography-time of flight mass spectrometry. Anal. Chim. Acta 883 (2015), 99–108, 10.1016/j.aca.2015.04.024.
Armstrong, P., Nizio, K.D., Perrault, K.A., Forbes, S.L., Establishing the volatile profile of pig carcasses as analogues for human decomposition during the early postmortem period. Heliyon, 2, 2016, e00070, 10.1016/j.heliyon.2016.e00070.
Dent, B.B., Forbes, S.L., Stuart, B.H., Review of human decomposition processes in soil. Environ. Geol. 45 (2004), 576–585, 10.1007/s00254-003-0913-z.
Knobel, Z., Ueland, M., Nizio, K.D., et al. A comparison of human and pig decomposition rates and odour profiles in an Australian environment. Aust. J. Forensic Sci. 51 (2019), 557–572, 10.1080/00450618.2018.1439100.
Deo, A., Forbes, S.L., Stuart, B.H., Ueland, M., Profiling the seasonal variability of decomposition odour from human remains in a temperate Australian environment. Aust. J. Forensic Sci., 2019, 1–11, 10.1080/00450618.2019.1637938.
Giles, S.B., Harrison, K., Errickson, D., Márquez-Grant, N., The effect of seasonality on the application of accumulated degree-days to estimate the early post-mortem interval. Forensic Sci. Int., 315, 2020, 10.1016/j.forsciint.2020.110419.
Forbes, S.L., Perrault, K.A., Stefanuto, P.-H., et al. Comparison of the decomposition VOC profile during winter and summer in a moist, mid-latitude (Cfb) climate. PLoS One, 9, 2014, e113681, 10.1371/journal.pone.0113681.
Kasper, J., Mumm, R., Ruther, J., The composition of carcass volatile profiles in relation to storage time and climate conditions. Forensic Sci. Int. 223 (2012), 64–71, 10.1016/j.forsciint.2012.08.001.
Can, I., Javan, G.T., Pozhitkov, A.E., Noble, P.A., Distinctive thanatomicrobiome signatures found in the blood and internal organs of humans. J. Microbiol. Methods 106 (2014), 1–7, 10.1016/J.MIMET.2014.07.026.
Stefanuto, P.-H., Perrault, K.A., Lloyd, R.M., et al. Exploring new dimensions in cadaveric decomposition odour analysis. Anal. Methods 7 (2015), 2287–2294, 10.1039/C5AY00371G.
Perrault, K.A., Stefanuto, P.-H., Stuart, B.H., et al. Reducing variation in decomposition odour profiling using comprehensive two-dimensional gas chromatography. J. Sep. Sci. 38 (2015), 73–80, 10.1002/jssc.201400935.
Forbes, S.L., Troobnikoff, A.N., Ueland, M., et al. Profiling the decomposition odour at the grave surface before and after probing. Forensic Sci. Int. 259 (2016), 193–199, 10.1016/j.forsciint.2015.12.038.
Dubois, L.M., Stefanuto, P.H., Heudt, L., et al. Characterizing decomposition odor from soil and adipocere samples at a death scene using HS-SPME-GC×GC-HRTOFMS. Forensic Chem 8 (2018), 11–20, 10.1016/j.forc.2018.01.001.
Dubois, L.M., Stefanuto, P.-H., Perrault, K.A., et al. Comprehensive approach for monitoring human tissue degradation. Chromatographia 82 (2019), 857–871, 10.1007/s10337-019-03710-3.
Rust, L., Nizio, K.D., Forbes, S.L., The influence of ageing and surface type on the odour profile of blood-detection dog training aids. Anal. Bioanal. Chem. 408 (2016), 6349–6360, 10.1007/s00216-016-9748-9.
Stefanuto, P.-H., Perrault, K., Grabherr, S., et al. Postmortem internal gas reservoir monitoring using GC × GC-HRTOF-MS. Separations, 3, 2016, 24, 10.3390/separations3030024.
Perrault, K.A., Stefanuto, P.-H., Dubois, L.M., et al. A minimally-invasive method for profiling volatile organic compounds within postmortem internal gas reservoirs. Int. J. Leg. Med. 131 (2017), 1271–1281, 10.1007/s00414-017-1621-7.
Nizio, K.D., Ueland, M., Stuart, B.H., Forbes, S.L., The analysis of textiles associated with decomposing remains as a natural training aid for cadaver-detection dogs. Forensic Chem 5 (2017), 33–45, 10.1016/J.FORC.2017.06.002.
Perrault, K.A., Nizio, K.D., Forbes, S.L., A comparison of one-dimensional and comprehensive two-dimensional gas chromatography for decomposition odour profiling using inter-year replicate field trials. Chromatographia 78 (2015), 1057–1070, 10.1007/s10337-015-2916-9.
Dubois, L.M., Perrault, K.A., Stefanuto, P.-H., et al. Thermal desorption comprehensive two-dimensional gas chromatography coupled to variable-energy electron ionization time-of-flight mass spectrometry for monitoring subtle changes in volatile organic compound profiles of human blood. J. Chromatogr. A 1501 (2017), 117–127, 10.1016/j.chroma.2017.04.026.
Stefanuto, P.-H., Perrault, K.A., Stadler, S., et al. GC×GC-TOFMS and supervised multivariate approaches to study human cadaveric decomposition olfactive signatures. Anal. Bioanal. Chem. 407 (2015), 4767–4778, 10.1007/s00216-015-8683-5.
Perrault, K.A., Stefanuto, P.-H., Dubois, L.M., et al. A minimally-invasive method for profiling volatile organic compounds within postmortem internal gas reservoirs. Int. J. Leg. Med. 131 (2017), 1271–1281, 10.1007/s00414-017-1621-7.
Sigman, M., Williams, M., Advances in fire debris analysis. Separations, 6, 2019, 13, 10.3390/separations6010013.
Cuzuel, V., Sizun, A., Cognon, G., et al. Human odor and forensics. Optimization of a comprehensive two-dimensional gas chromatography method based on orthogonality: how not to choose between criteria. J. Chromatogr. A 1536 (2018), 58–66, 10.1016/j.chroma.2017.08.060.
Doležal, P., Kyjaková, P., Valterová, I., Urban, Š., Qualitative analyses of less-volatile organic molecules from female skin scents by comprehensive two dimensional gas chromatography–time of flight mass spectrometry. J. Chromatogr. A 1505 (2017), 77–86, 10.1016/j.chroma.2017.04.062.
Ueland, M., Ewart, K., Troobnikoff, A.N., et al. A rapid chemical odour profiling method for the identification of rhinoceros horns. Forensic Sci. Int. 266 (2016), e99–e102, 10.1016/j.forsciint.2016.05.011.
Abel, R.J., Lunder, J.L., Harynuk, J.J., A novel protocol for producing low-abundance targets to characterize the sensitivity limits of ignitable liquid detection canines. Forensic Chem, 18, 2020, 100230, 10.1016/j.forc.2020.100230.
Almirall, J., Arkes, H., Lentini, J., et al. AAAS, Forensic Science Assessments: A Quality and Gap Analysis- Fire Investigation. 2017, 1–89, 10.1126/srhrl.aag2872.
O'Brien, É., Daeid, N.N., Black, S., Science in the court: pitfalls, challenges and solutions. Philos Trans R Soc B Biol Sci, 370, 2015, 10.1098/rstb.2015.0062.
Frysinger, G.S., Gaines, R.B., Reddy, C.M., GC×GC—a new analytical tool for environmental forensics. Environ Forensics 3 (2002), 27–34, 10.1080/713848318.
Taylor, C., An arson investigation by using comprehensive two-dimensional gas chromatography-quadrupole mass spectrometry. J Forensic Res, 03, 2012, 10.4172/2157-7145.1000169.
Nizio, K., Cochran, J., Forbes, S., Achieving a near-theoretical maximum in peak capacity gain for the forensic analysis of ignitable liquids using GC×GC-TOFMS. Separations, 3, 2016, 26, 10.3390/separations3030026.
Lopatka, M., Sampat, A.A., Jonkers, S., et al. Local ion signatures (LIS) for the examination of comprehensive two-dimensional gas chromatography applied to fire debris analysis. Forensic Chem 3 (2017), 1–13, 10.1016/j.forc.2016.10.003.
Abel, R.J., Zadora, G., Sandercock, P.M.L., Harynuk, J.J., Modern instrumental limits of identification of ignitable liquids in forensic fire debris analysis. Separations 5 (2018), 1–18, 10.3390/separations5040058.
Pandohee, J., Hughes, J.G., Pearson, J.R., Jones O, A.H., Chemical fingerprinting of petrochemicals for arson investigations using two-dimensional gas chromatography - flame ionisation detection and multivariate analysis. Sci. Justice 60 (2020), 381–387, 10.1016/j.scijus.2020.04.004.
Sampat, A.A.S., Van, D.B., Lopatka, M., et al. Detection and characterization of ignitable liquid residues in forensic fire debris samples by comprehensive two-dimensional gas chromatography. Separations, 5, 2018, 43, 10.3390/separations5030043.
Boegelsack, N., Sandau, C., McMartin, D.W., et al. Development of retention time indices for comprehensive multidimensional gas chromatography and application to ignitable liquid residue mapping in wildfire investigations. J. Chromatogr. A, 1635, 2021, 10.1016/j.chroma.2020.461717.
Kates, L.N., Richards, P.I., Sandau, C.D., The application of comprehensive two-dimensional gas chromatography to the analysis of wildfire debris for ignitable liquid residue. Forensic Sci. Int., 310, 2020, 10.1016/j.forsciint.2020.110256.
Stauffer, E., Dolan, J., Newman, R., Fire Debris Analysis. 1st ed., 2007, Elsevier.
Cordero, C., Kiefl, J., Schieberle, P., et al. Comprehensive two-dimensional gas chromatography and food sensory properties: potential and challenges. Anal. Bioanal. Chem. 407 (2015), 169–191, 10.1007/s00216-014-8248-z.
Schwemer, T., Rössler, T., Ahrens, B., et al. Characterization of a heroin manufacturing process based on acidic extracts by combining complementary information from two-dimensional gas chromatography and high resolution mass spectrometry. Forensic Chem 4 (2017), 9–18, 10.1016/j.forc.2017.02.006.
Franchina, F.A., Dubois, L.M., Focant, J.-F., In-depth Cannabis multiclass metabolite profiling using Sorptive extraction and multidimensional gas chromatography with low- and high-resolution mass spectrometry. Anal Chem, 2020, 10.1021/acs.analchem.0c01301.
Stefanuto, P.-H., Perrault, K., Focant, J.-F., Forbes, S., Fast chromatographic method for explosive profiling. Chromatography 2 (2015), 213–224, 10.3390/chromatography2020213.
Tsai, C.W., Milam, S.J., Tipple, C.A., Exploring the analysis and differentiation of plastic explosives by comprehensive multidimensional gas chromatography-mass spectrometry (GC × GC–MS) with a statistical approach. Forensic Chem 6 (2017), 10–18, 10.1016/j.forc.2017.08.003.
Strozier, E.D., Mooney, D.D., Friedenberg, D.A., et al. Use of comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometric detection and random Forest pattern recognition techniques for classifying chemical threat agents and detecting chemical attribution signatures. Anal. Chem. 88 (2016), 7068–7075, 10.1021/acs.analchem.6b00725.
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