Article (Scientific journals)
Neurophysiological Biomarkers of Persistent Post-Concussive Symptoms: A Scoping Reveiw
Mortaheb, Sepehr; Filippini, Maria Maddalena; Kaux, Jean-François et al.
2021In Frontiers in Neurology, 12, p. 687197
Peer Reviewed verified by ORBi
 

Files


Full Text
Final_Publishe_Version.pdf
Publisher postprint (1.37 MB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] Background and Objectives: Persistent post-concussive symptoms (PCS) consist of neurologic and psychological complaints persisting after a mild traumatic brain injury (mTBI). It affects up to 50% of mTBI patients, may cause long-term disability, and reduce patients’ quality of life. The aim of this review was to examine the possible use of different neuroimaging modalities in PCS. Methods: Articles from Pubmed database were screened to extract studies that investigated the relationship between any neuroimaging features and symptoms of PCS. Descriptive statistics were applied to report the results. Results: A total of 80 out of 939 papers were included in the final review. Ten examined conventional MRI (30% positive finding), 24 examined diffusion weighted imaging (54.17% positive finding), 23 examined functional MRI (82.61% positive finding), nine examined electro(magneto)encephalography (77.78% positive finding), and 14 examined other techniques (71% positive finding). Conclusion: MRI was the most widely used technique, while functional techniques seem to be the most sensitive tools to evaluate PCS. The common functional patterns associated with symptoms of PCS were a decreased anti-correlation between the default mode network and the task positive network and reduced brain activity in specific areas (most often in the prefrontal cortex). Significance: Our findings highlight the importance to use functional approaches which demonstrated a functional alteration in brain connectivity and activity in most studies assessing PCS.
Disciplines :
Neurology
Author, co-author :
Mortaheb, Sepehr  ;  Université de Liège - ULiège > GIGA Consciousness - Physiology of Cognition
Filippini, Maria Maddalena;  Azienda Unita Sanitaria Locale-Istituto di Ricovero e Cura a Carattere Scientifico (USL-IRCSS) di Reggio Emilia > Neuromotor and Rehabilitation Department
Kaux, Jean-François  ;  Université de Liège - ULiège > Département des sciences de la motricité > Médecine physique, réadaptation et traumatologie du sport
Annen, Jitka  ;  Université de Liège - ULiège > GIGA Consciousness - Coma Science Group ; CHU Liège - Central University Hospital of Liege > Centre du Cerveau²
Lejeune, Nicolas  ;  Université de Liège - ULiège > GIGA Consciousness - Coma Science Group
Martens, Géraldine  ;  Université de Liège - ULiège > Département des sciences de la motricité > Kinésithérapie générale et réadaptation
calderon, Maria Antonia Fuentes;  Neurorehabilitation (NEURORHB) Servicio de Neurorrehabilitación de Hospitales Vithas
LAUREYS, Steven  ;  Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Centre du Cerveau²
Thibaut, Aurore ;  Université de Liège - ULiège > GIGA > GIGA Consciousness - Coma Science Group ; CHU Liège - Centre Hospitalier Universitaire de Liège > Centre du Cerveau²
Language :
English
Title :
Neurophysiological Biomarkers of Persistent Post-Concussive Symptoms: A Scoping Reveiw
Publication date :
September 2021
Journal title :
Frontiers in Neurology
eISSN :
1664-2295
Publisher :
Frontiers Media S.A., Switzerland
Volume :
12
Pages :
687197
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 01 November 2021

Statistics


Number of views
157 (9 by ULiège)
Number of downloads
131 (6 by ULiège)

Scopus citations®
 
5
Scopus citations®
without self-citations
5
OpenCitations
 
2

Bibliography


Similar publications



Contact ORBi