Poster (Scientific congresses and symposiums)
Optimisation of novel 3D composite scaffolds for bone reconstruction
Monteiro, Ana; Pérez Jiménez, Aurora Fernanda; Plougonven, Erwan et al.
202131th Conference of the European Society for Biomaterials, ESB 2021
 

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Monteiro et al -European Society for Biomaterials (ESB) September 5th 2021 rev ChG 110321_SL.pdf
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Keywords :
scaffold; bone reconstruction
Abstract :
[en] Custom-made scaffold-mediated regeneration is an emergent field in bone reconstruction. However, the optimization of 3D degradable implants with suitable biological response and mechanical features still remains challenging today. The focus of this study was to tailor a 3D scaffold made from a polymeric macroporous matrix filled with hydroxyapatite (HA) and amphiphilic hydrogel. Accordingly, three different implant designs composed of PLA have been developped by 3D printing with various interconnected porous in an optimal range of 200 to 400 µm. In a second step, the scaffolds have been filled with an amphiphilic gel containing HA in order to optimize the dissolution rate of the gel and its ability to enhance cell colonisation and proliferation.
Disciplines :
Materials science & engineering
Author, co-author :
Monteiro, Ana ;  Université de Liège - ULiège > CEIB
Pérez Jiménez, Aurora Fernanda ;  Université de Liège - ULiège > CEIB
Plougonven, Erwan  ;  Université de Liège - ULiège > Department of Chemical Engineering > PEPs - Products, Environment, and Processes
Lambert, Stéphanie  ;  Université de Liège - ULiège > Department of Chemical Engineering > Nanomaterials, Catalysis, Electrochemistry
Grandfils, Christian ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine
Language :
English
Title :
Optimisation of novel 3D composite scaffolds for bone reconstruction
Publication date :
September 2021
Event name :
31th Conference of the European Society for Biomaterials, ESB 2021
Event date :
du 5 au 9 septembre 2021
Audience :
International
Available on ORBi :
since 13 October 2021

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