Article (Scientific journals)
Determinants of IBD-related disability: a cross-sectional survey from the GETAID.
Tannoury, Jenny; Nachury, Maria; Martins, Carole et al.
2021In Alimentary pharmacology & therapeutics, 53 (10), p. 1098-1107
Peer reviewed
 

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Keywords :
Colitis, Ulcerative; Cross-Sectional Studies; Disability Evaluation; France/epidemiology; Humans; Inflammatory Bowel Diseases/epidemiology/therapy; Male
Abstract :
[en] BACKGROUND: The burden of inflammatory bowel disease (IBD) is rising worldwide. The goal of IBD treatment is to achieve clinical and endoscopic remission but also prevent disability. AIMS: To identify the predictive factors of disability in a large population of patients with IBD. PATIENTS AND METHODS: We conducted a cross-sectional survey in 42 tertiary centres in France and Belgium. A self-administered questionnaire was designed to explore patients and their IBD characteristics. IBD-disk is a validated tool to measure disability in patients with IBD. The IBD-disk score was then calculated for each patient. Based on a previous study, an overall IBD-disk score ≥40 was associated with moderate-to-severe disability. RESULTS: Among the 2011 patients, 1700 were analysed, including 746 (44%) in self-reported clinical remission and 752 (44.2%) declaring clinical activity. The patient global assessment of global remission was missing in 200 (11.8%) of 1700 patients. Moderate-to-severe disability was significantly increased in patients with BMI >25 kg/m(2) (OR = 1.66; 95% CI [1.29-2.14]), in those having perception of need for a psychotherapist (OR = 2.24; 95% CI [1.79-3.05]) and social worker (OR = 1.54; 95% CI [1.08-2.21]). Conversely, male gender (OR = 0.83; 95% CI [0.69-0.99]), ulcerative colitis (OR = 0.69; 95% CI [0.53-0.92]), self-reported clinical remission (OR = 0.59; 95% CI [0.46-0.77]) and employed or student occupational status (OR = 0.69; 95% CI [0.52-0.92]) were inversely correlated with disability. Overall, 257 (34.5%) patients who declared being in clinical remission had disability. CONCLUSION: Determinants of IBD-related disability include IBD-related factors but also psychological and social factors. This highlights the importance of a multidisciplinary team in the management of patients with IBD.
Disciplines :
Gastroenterology & hepatology
Author, co-author :
Tannoury, Jenny
Nachury, Maria
Martins, Carole
Serrero, Melanie
Filippi, Jerome
Roblin, Xavier
Bourrier, Anne
Bouguen, Guillaume
Franchimont, Denis
Savoye, Guillaume
Buisson, Anthony
Louis, Edouard  ;  Université de Liège - ULiège > Département des sciences cliniques > Hépato-gastroentérologie
Nancey, Stephane
Abitbol, Vered
Reimund, Jean-Marie
DeWitt, Olivier
Vuitton, Lucine
Mathieu, Nicolas
Peyrin-Biroulet, Laurent
Gilletta, Cyrielle
Allez, Matthieu
Viennot, Stephanie
Trang-Poisson, Caroline
Laharie, David
Amiot, Aurelien
More authors (15 more) Less
Language :
English
Title :
Determinants of IBD-related disability: a cross-sectional survey from the GETAID.
Publication date :
2021
Journal title :
Alimentary pharmacology & therapeutics
ISSN :
0269-2813
eISSN :
1365-2036
Volume :
53
Issue :
10
Pages :
1098-1107
Peer reviewed :
Peer reviewed
Commentary :
© 2021 John Wiley & Sons Ltd.
Available on ORBi :
since 30 September 2021

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