Radiothérapie externe; Radiothérapie FLASH; Radiobiologie; Distribution de la dose; Optimisation de la dose; External beam radiation therapy; Dose optimization; Dose distribution; Radiobiology; FLASH radiotherapy
Abstract :
[fr] La radiothérapie s’est installée au 20ème siècle comme une modalité incontournable dans la lutte contre le cancer. Les avancées technologiques majeures des dernières décennies ont permis une amélioration considérable de la fenêtre thérapeutique. Elles ont également ouvert la voie à la radiothérapie stéréotaxique et à de nouvelles indications. Cet article a pour objectif de permettre aux lecteurs de comprendre la radiothérapie externe en 2021 et d’en appréhender les enjeux de demain. Trois axes d’amélioration de la discipline seront décrits, l’optimisation de la dose thérapeutique prescrite, l’amélioration de la distribution de cette dose et, finalement, la meilleure compréhension de la radiobiologie. Pour chacun de ces axes, des implications actuelles seront données ainsi que celles qui pourraient/ devraient avoir un impact sur la radiothérapie future. La radiothérapie FLASH sera, par exemple, abordée. [en] Radiotherapy established itself in the 20th century as an essential modality in the fight against cancer. The major technological advances of the last decades have allowed a considerable improvement in the therapeutic window. They have also paved the way for stereotactic radiotherapy and new indications. The aim of this article is to enable readers to understand external radiotherapy in 2021 and to understand the challenges of tomorrow. Three areas of improvement in the discipline will be described, the optimization of the prescribed therapeutic dose, the improvement of the distribution of this dose and, finally, the better understanding of radiobiology. For each of these axes, the current implications will be described as well as those which could/should have a major impact on the radiotherapy. FLASH radiotherapy will also be discussed.
Disciplines :
Oncology
Author, co-author :
Colin, Gilles ; Centre Hospitalier Universitaire de Liège - CHU > Département de Physique Médicale > Service médical de radiothérapie
COUCKE, Philippe ; Centre Hospitalier Universitaire de Liège - CHU > Département de Physique Médicale > Service médical de radiothérapie
Language :
French
Title :
Comment améliorer la radiothérapie ? évolutions teChnologiques et radiothérapie de demain
Alternative titles :
[en] how to improve radiotherapy ? teChnologiCal developments and radiotherapy of tomorrow
Publication date :
2021
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
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