Newman, D.J., Cragg, G.M., Natural products as sources of new drugs over the 30 years from 1981 to 2010 (2012) J. Nat. Prod, 75, pp. 311-335. , [CrossRef] [PubMed]
Cragg, G.M., Newman, D.J., Natural products: A continuing source of novel drug leads (2013) Biochim. Biophys. Acta, 1830, pp. 3670-3695. , [CrossRef]
(2013) WHO Traditional Medicine Strategy: 2014–2023, , WHO. WHO: Geneva, Switzerland, ISBN 978 92 4 150609 0
Shen, B., A New Golden Age of Natural Products Drug Discovery (2015) Cell, 163, pp. 1297-1300. , [CrossRef]
Globocan 2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012, , http://globocan.iarc.fr/Pages/online.aspx, WHO. (accessed on 27 February 2021)
Human Papillomavirus (HPV) and Cervical Cancer, , http://www.who.int/mediacentre/factsheets/fs380/en/, World Health Organization. (accessed on 26 March 2018)
Elmore, S., Apoptosis: A review of programmed cell death (2007) Toxicol. Pathol, 35, pp. 495-516. , [CrossRef] [PubMed]
D’Arcy, M.S., Cell death: A review of the major forms of apoptosis, necrosis and autophagy (2019) Cell Biol. Int, 43, pp. 582-592. , [CrossRef]
Cavalcante, G.C., Schaan, A.P., Cabral, G.F., Santana-da-Silva, M.N., Pinto, P., Vidal, A.F., Ribeiro-Dos-Santos, Â., A Cell’s Fate: An Overview of the Molecular Biology and Genetics of Apoptosis (2019) Int. J. Mol. Sci, 20, p. 4133. , [CrossRef]
Levine, A.J., p53, the cellular gatekeeper for growth and division (1997) Cell, 88, p. 323. , [CrossRef]
Vogelstein, B., Lane, D., Levine, A.J., Surfing the p53 network (2000) Nature, 408, pp. 307-310. , [CrossRef] [PubMed]
Agarwal, M.L., Taylor, W.R., Chernov, M.V., Chernova, O.B., Stark, G.R., The p53 network (1998) J. Biol. Chem, 273, p. 1. , [CrossRef]
Al-Khalaf, H.H., Aboussekhra, A., p16(INK4A) positively regulates p21(WAF1) expression by suppressing AUF1-dependent mRNA decay (2013) PLoS ONE, 8, p. e70133. , [CrossRef] [PubMed]
Jeong, J.H., Kang, S.S., Park, K.K., Chang, H.W., Magae, J., Chang, Y.C., p53-independent induction of G1 arrest and p21WAF1/CIP1 expression by ascofuranone, an isoprenoid antibiotic, through downregulation of c-Myc (2010) Mol. Cancer Ther, 9, pp. 2102-2113. , [CrossRef] [PubMed]
Ho, C.J., Lin, R.W., Zhu, W.H., Wen, T.K., Hu, C.J., Lee, Y.L., Hung, T.I., Wang, C., Transcription-independent and-dependent p53-mediated apoptosis in response to genotoxic and non-genotoxic stress (2019) Cell Death. Discov, 5, p. 131. , [CrossRef]
Junaid, S., Dileep, N., Rakesh, K.N., Prashith, K.T.R., Raghavendra, H.L., Contents of total phenolics and flavonoids, radical scavenging and anticaries activity of leaf and seed extract of Anisomeles indica Linn (2013) Int. J. Drug. Dev. Res, 5, pp. 286-292
Melkani, A.B., Mohan, L., Pant, C.C., Diterpene rich essential oil from Anisomeles indica (L.) o. kuntz. and its antimicrobial activity (2016) World J. Pharma. Res, 5, pp. 932-943
Yu, C.Y., Jerry-Teng, C.L., Hung, P.S., Cheng, C.C., Hsu, S.L., Hwang, G.Y., Tzeng, Y.M., Ovatodiolide isolated from Anisomeles indica induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling pathways (2018) Eur. J. Pharmacol, 819, pp. 16-29. , [CrossRef]
Lien, H.M., Wang, C.Y., Chang, H.Y., Huang, C.L., Peng, M.T., Sing, Y.T., Chen, C.C., Lai, C.H., Bioevaluation of Anisomeles indica extracts and their inhibitory effects on Helicobacter pylori-mediated inflammation (2013) J. Ethnopharmacol, 145, pp. 397-401. , [CrossRef]
Hou, Y.Y., Wu, M.L., Hwang, Y.C., Chang, F.R., Wu, Y.C., Wu, C.C., The natural diterpenoid ovatodiolide induces cell cycle arrest and apoptosis in human oral squamous cell carcinoma Ca9-22 cells (2009) Life Sci, 85, pp. 26-32. , [CrossRef] [PubMed]
Liao, Y.F., Rao, Y.K., Tzeng, Y.M., Aqueous extract of Anisomeles indica and its purified compound exerts anti-metastatic activity through inhibition of NF-κB/AP-1-dependent MMP-9 activation in human breast cancer MCF-7 cells (2012) Food Chem. Toxicol, 50, pp. 2930-2936. , [CrossRef] [PubMed]
Lawson, N.D., Weinstein, B.M., In vivo imaging of embryonic vascular development using transgenic zebrafish (2002) Dev. Biol, 248, pp. 307-318. , [CrossRef] [PubMed]
(2002) OECD Test No. 423: Acute Oral Toxicity—Acute Toxic Class Method, , OECD Publishing. OECD Publishing: Paris, France
Wijesundara, N.M., Rupasinghe, H., Bactericidal and Anti-Biofilm Activity of Ethanol Extracts Derived from Selected Medicinal Plants against Streptococcus pyogenes (2019) Molecules, 24, p. 1165. , [CrossRef] [PubMed]
Mosmann, T., Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays (1983) J. Immunol. Methods, 65, pp. 55-63. , [CrossRef]
Schutte, B., Nuydens, R., Geerts, H., Ramaekers, F., Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells (1998) J. Neurosci. Methods, 86, pp. 63-69. , [CrossRef]
Darzynkiewicz, Z., Huang, X., Zhao, H., Analysis of Cellular DNA Content by Flow Cytometry (2017) Curr. Protoc. Cytom, 82. , 7.5.1–7.5.20
Ohgami, N., Yamanoshita, O., Thang, N.D., Yajima, I., Nakano, C., Wenting, W., Ohnuma, S., Kato, M., Carcinogenic risk of chromium, copper and arsenic in CCA-treated wood (2015) Environ. Pollut, 206, pp. 456-460. , [CrossRef]
Thang, N.D., Yajima, I., Kumasaka, M.Y., Kato, M., Bidirectional functions of arsenic as a carcinogen and an anti-cancer agent in human squamous cell carcinoma (2014) PLoS ONE, 9, p. e96945. , [CrossRef]
Lu, K.T., Wang, B.Y., Chi, W.Y., Chang-Chien, J., Yang, J.J., Lee, H.T., Tzeng, Y.M., Chang, W.W., Ovatodiolide Inhibits Breast Cancer Stem/Progenitor Cells through SMURF2-Mediated Downregulation of Hsp27 (2016) Toxins, 8, p. 127. , [CrossRef]
Lin, K.L., Tsai, P.C., Hsieh, C.Y., Chang, L.S., Lin, S.R., Antimetastatic effect and mechanism of ovatodiolide in MDA-MB-231 human breast cancer cells (2011) Chem. Biol. Interact, 194, pp. 148-158. , [CrossRef]
Koster, R., Timmer-Bosscha, H., Bischoff, R., Gietema, J.A., de Jong, S., Disruption of the MDM2-p53 interaction strongly potentiates p53-dependent apoptosis in cisplatin-resistant human testicular carcinoma cells via the Fas/FasL pathway (2011) Cell. Death Dis, 2, p. e148. , [CrossRef]
Lanni, J.S., Lowe, S.W., Licitra, E.J., Liu, J.O., Jacks, T., p53-independent apoptosis induced by paclitaxel through an indirect mechanism (1997) Proc. Natl. Acad. Sci. USA, 94, pp. 9679-9683. , [CrossRef]
Leong, W.F., Chau, J.F., Li, B., p53 Deficiency leads to compensatory up-regulation of p16INK4a (2009) Mol. Cancer Res, 7, pp. 354-360. , [CrossRef] [PubMed]
Pines, J., Cyclins: Wheels within wheels (1991) Cell Growth Differ, 2, p. 305. , [PubMed]
Sherr, C.J., G1 phase progression: Cycling on cue (1994) Cell, 79, p. 551. , [CrossRef]
Ohtsubo, M., Theodoras, A.M., Schumacher, J., Roberts, J.M., Pagano, M., Human cyclin E, a nuclear protein essential for the G1-to-S phase transition (1995) Mol. Cell. Biol, 15, p. 2612. , [CrossRef] [PubMed]
Girard, F., Strausfeld, U., Fernandez, A., Lamb, N.J., Cyclin A is required for the onset of DNA replication in mammalian fibroblasts (1991) Cell, 67, p. 1169. , [CrossRef]
Arellano, M., Moreno, S., Regulation of CDK/cyclin complexes during the cell cycle (1997) Int. J. Biochem. Cell Biol, 29, p. 559. , [CrossRef]
Ko, L.J., Prives, C., p53: Puzzle and paradigm (1996) Genes Dev, 10, p. 1054. , [CrossRef] [PubMed]
Li, Z., Zhao, J., Du, Y., Park, H.R., Sun, S.Y., Bernal-Mizrachi, L., Aitken, A., Fu, H., Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation (2008) Proc. Natl. Acad. Sci. USA, 105, pp. 162-167. , [CrossRef]
Weinberg, F., Hamanaka, R., Wheaton, W.W., Weinberg, S., Joseph, J., Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity (2010) Proc. Natl. Acad. Sci. USA, 107, pp. 8788-8793. , [CrossRef] [PubMed]
Yao, J., He, H., Xue, J., Wang, J., Jin, H., Wu, J., Hu, J., Kuchta, K., Mori Ramulus (Chin.Ph.)-the Dried Twigs of Morus alba L./Part 1: Discovery of Two Novel Coumarin Glycosides from the Anti-Hyperuricemic Ethanol Extract (2018) Molecules, 24, p. 629. , [CrossRef]
Gori, A., Ferrini, F., Marzano, M.C., Tattini, M., Centritto, M., Baratto, M.C., Pogni, R., Brunetti, C., Characterisation and Antioxidant Activity of Crude Extract and Polyphenolic Rich Fractions from C. incanus Leaves (2016) Int. J. Mol. Sci, 17, p. 1344. , [CrossRef]
Adnan, M., Oh, K.K., Azad, M.O.K., Shin, M.H., Wang, M.H., Cho, D.H., Kenaf (Hibiscus cannabinus L.) Leaves and Seed as a Potential Source of the Bioactive Compounds: Effects of Various Extraction Solvents on Biological Properties (2020) Life, 10, p. 223. , [CrossRef] [PubMed]
Attimarad, M., Ahmed, K.K., Aldhubaib, B.E., Harsha, S., High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery (2011) Pharm. Methods, 2, pp. 71-75. , [CrossRef] [PubMed]
Razafindrakoto, Z.R., Donno, D., Tombozara, N., Andriamaniraka, H., Andrianjara, C., Ramanitrahasimbola, D., Beccaro, G.L., Antioxidant, Anti-Inflammatory, and Antidiabetic Activities of Leaves and Stems of Uapaca bojeri Bail. (EUPHORBIACEAE), an Endemic Plant of Madagascar (2020) Pharmaceuticals, 13, p. 71. , [CrossRef] [PubMed]
