Etude de la variabilite interindividuelle de la variation contingente negative (VCN)

[en] The use of CNV in clinical practice requires the choice of a standardised protocol, the constitution of reference normative data and the consideration of intra- and interindividual variability. For this purpose, we recorded CNV in 86 control subjects (44 men and 42 women, 18 to 62 years old (mean age = 34 +/- 13 years) during a reaction time paradigm with a warning signal and a 1-second S1-S2 interval. Moreover, the role of inter-stimulation interval was analysed in a group of 12 subjects through the comparison of recordings made with 1- and 3-second intervals. The CNV amplitude, its morphology and topographic distribution as well as its resolution mode and evolution through the recording were studied. The subjects' performances and their interactions with electroencephalographic data were also included in the analyses. Our results underscore the contribution of age and gender and psychological factors to CNV variability. CNV amplitude (both M1 and M2) increased and changed topographic distribution toward more central sites in older. Men had faster reaction times than women and lower post-S1 P300. Moreover, the life events-related stress and the subject's current anxiety level were accompanied by a decreased CNV amplitude.

Disciplines :

Neurosciences & behavior

Author, co-author :

Crasson, Marion ; Université de Liège - ULiège > Département des sciences cliniques > Psychiatrie et psychologie médicale

Lembreghts, M.

el Ahmadi, A.

Legros, Jean-Jacques ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques

Timsit-Berthier, M.

Language :

French

Title :

Etude de la variabilite interindividuelle de la variation contingente negative (VCN)

Alternative titles :

[en] Interindividual Variability of Contingent Negative Variation

Publication date :

October 2001

Journal title :

Neurophysiologie Clinique

ISSN :

0987-7053

eISSN :

1769-7131

Publisher :

Elsevier, United States - New York

Volume :

Issue :

Pages :

300-20

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 22 October 2009

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