Article (Scientific journals)
Variations in dried blood spot immunoreactive trypsin in relation to gestational age and during the first week of life
Bourguignon, Jean-Pierre; Deby-Dupont, G.; Reuter, A. et al.
1986In European Journal of Pediatrics, 144 (6), p. 547-549
Peer Reviewed verified by ORBi
 

Files


Full Text
Bourguignon_VariationsInDriedBloodSpot_1986.pdf
Publisher postprint (309.99 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Immunoreactive trypsin; Premature newborns; Blood stains; Gestational age; Radioimmunoassay; Trypsin
Abstract :
[en] Dry blood spot immunoreactive trypsin was measured by radioimmunoassay in 84 preterm babies and in 65 full-term newborns studied daily from the first to the fifth day of life. In a control group of 3858 full-term newborns, trypsin concentrations at days 4-6 of life exhibited a log-normal pattern distribution, the geometric mean being 18 ng/ml serum. Immunoreactive trypsin concentrations did not change significantly between days 1, 2, 3, 4 and 5 after birth. Immunoreactive trypsin was found to be significantly lower (geometric mean 9 ng/ml, P<0.01) in preterm newborns before 32 weeks of gestation. In hypotrophic newborns of 34 weeks gestational age, immunoreactive trypsin values were higher than those observed at 31 weeks of gestation in eutrophic newborns, the mean birth weight not being different between both groups. These data suggest that trypsin production by the pancreas is dependent on maturity but does not seem related to intrauterine nutritional status. Immunoreactive trypsin concentrations do not change after 32 weeks gestational age and during the first postnatal week.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Bourguignon, Jean-Pierre ;  Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Deby-Dupont, G.;  Université de Liège - ULiège > Laboratoire de Radioimmunologie
Reuter, A.
Senterre, J.;  Université de Liège - ULiège > Clinique Pédiatrique
Gerard, Arlette;  Université de Liège - ULiège > Laboratoire de Radioimmunologie
Franchimont, Paul;  Université de Liège - ULiège > Laboratoire de Radioimmunologie
Language :
English
Title :
Variations in dried blood spot immunoreactive trypsin in relation to gestational age and during the first week of life
Publication date :
1986
Journal title :
European Journal of Pediatrics
ISSN :
0340-6199
eISSN :
1432-1076
Publisher :
Springer, Germany
Volume :
144
Issue :
6
Pages :
547-549
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 17 May 2021

Statistics


Number of views
26 (1 by ULiège)
Number of downloads
84 (1 by ULiège)

Scopus citations®
 
7
Scopus citations®
without self-citations
6
OpenCitations
 
7

Bibliography


Similar publications



Contact ORBi