Reference : Applications de l'extraction et du dosage radioimmunologique du LH-RH dans les urines...
Scientific journals : Article
Human health sciences : Endocrinology, metabolism & nutrition
Applications de l'extraction et du dosage radioimmunologique du LH-RH dans les urines humaines
[en] Use of radioimmunology determination of LH RH in human urine
Bourguignon, Jean-Pierre mailto [Université de Liège - ULiège > Département des sciences cliniques > Pédiatrie > >]
Dourcy, C. [> > > >]
Franchimont, Paul [> >]
Comptes Rendus des Séances de la Société de Biologie et de ses Filiales
Masson Publishing
Yes (verified by ORBi)
[en] Human ; Animal ; Synthetic hormones ; Menopause ; Female ; Gonadorelin
[en] The existence of endogenous LH-RH like immunoreactivity is shown in human urines after appropriate extraction, by the radioimmunoassay of LH-RH. In normally cycling and menopausal women the quantities of endogenous hormone found in urines are greater after acid extraction than those found after extraction at pH 7. Furthermore, the increase observed by extraction in acidified methanol is directly correlated and proportional to the quantity of hormone assayable by extraction at pH 7. The hypothesis of urinary excretion of LH-RH as a polymer of immunoreactive units is suggested by this study.
Researchers ; Professionals ; Students

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