[en] The excretion of immunoreactive and radioactive material in urine was studied after intravenous injection of synthetic LH-RH in the rabbit and in man. The LH-RH-like immunoreactive substance (LHRH-LIS) found in unextracted urine by radioimmunoassay was excreted within the same time lag and in the same proportions in the rabbit and in the human. The urinary LHRH-LIS showed immunological properties identical to those of synthetic LH-RH. The physicochemical properties of the urinary LHRH-LIS were similar in the rabbit and in the human, but different from those of synthetic LH-RH, as shown by purifications on sephadex.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Bourguignon, Jean-Pierre ; Université de Liège - ULiège > Département des sciences cliniques > Pédiatrie
Leinartz-Dourcy, C.
Franchimont, Paul
Language :
French
Title :
Excrétion urinaire du LH-RH après injection intraveineuse chez le lapin et chez l'homme
Alternative titles :
[en] Urinary excretion of LH RH after i.v. injection in rabbit and man
Publication date :
1977
Journal title :
Comptes Rendus des Séances de la Société de Biologie et de ses Filiales
