Article (Scientific journals)
Nutritional interventions to improve muscle mass, muscle strength, and physical performance in older people: an umbrella review of systematic reviews and meta-analyses
Gielen, Evelien; Beckwée, David; Delaere, Andreas et al.
2021In Nutrition Reviews, 79 (2), p. 121-147
Peer Reviewed verified by ORBi
 

Files


Full Text
Nutritional interventions to improve muscle mass....pdf
Publisher postprint (715.03 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
diet; exercise; intervention; sarcopenia
Abstract :
[en] Context: Sarcopenia is a progressive and generalized skeletal muscle disorder associated with an increased risk of adverse outcomes such as falls, disability, and death. The Belgian Society of Gerontology and Geriatrics has developed evidencebased guidelines for the prevention and treatment of sarcopenia. This umbrella review presents the results of the Working Group on Nutritional Interventions. Objective: The aim of this umbrella review was to provide an evidence-based overview of nutritional interventions targeting sarcopenia or at least 1 of the 3 sarcopenia criteria (ie, muscle mass, muscle strength, or physical performance) in persons aged 65 years. Data sources: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, the PubMed and Web of Science databases were searched for systematic reviews and meta-analyses reporting the effect of nutritional supplementation on sarcopenia or muscle mass, strength, or physical performance. Data extraction: Two authors extracted data on the key characteristics of the reviews, including participants, treatment, and outcomes. Methodological quality of the reviews was assessed using the product A Measurement Tool to Assess Systematic Reviews. Three authors synthesized the extracted data and generated recommendations on the basis of an overall synthesis of the effects of each intervention. Quality of evidence was rated with the Grading of Recommendations Assessment, Development and Evaluation approach. Data analysis: A total of 15 systematic reviews were included. The following supplements were examined: proteins, essential amino acids, leucine, b-hydroxy-b-methylbutyrate, creatine, and multinutrient supplementation (with or without physical exercise). Because of both the low amount and the low to moderate quality of the reviews, the level of evidence supporting most recommendations was low to moderate. Conclusions: Best evidence is available to recommend leucine, because it has a significant effect on muscle mass in elderly people with sarcopenia. Protein supplementation on top of resistance training is recommended to increase muscle mass and strength, in particular for obese persons and for >=24weeks. Effects on sarcopenia as a construct were not reported in the included reviews.
Disciplines :
Public health, health care sciences & services
Author, co-author :
Gielen, Evelien
Beckwée, David
Delaere, Andreas
De Breucker, Sandra
Vandewoude, Maurits
Bautmans, Ivan
Beaudart, Charlotte ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Beyer, I.
Bruyère, Olivier  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
De Cock, A.-M.
de Saint-Hubert, M.
De Spiegeleer, A.
Perkisas, S.
More authors (3 more) Less
Language :
English
Title :
Nutritional interventions to improve muscle mass, muscle strength, and physical performance in older people: an umbrella review of systematic reviews and meta-analyses
Publication date :
2021
Journal title :
Nutrition Reviews
ISSN :
0029-6643
Publisher :
International Life Sciences Institute
Volume :
79
Issue :
2
Pages :
121-147
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
the Sarcopenia Guidelines Development Group of the Belgian Society of Gerontology and Geriatrics (BSGG)
Available on ORBi :
since 22 March 2021

Statistics


Number of views
2098 (5 by ULiège)
Number of downloads
1274 (3 by ULiège)

Scopus citations®
 
109
Scopus citations®
without self-citations
104
OpenCitations
 
64

Bibliography


Similar publications



Contact ORBi