COVID-19 et asthme.

Administration, Inhalation; Adrenal Cortex Hormones/therapeutic use; Anti-Asthmatic Agents/therapeutic use; Asthma/drug therapy/epidemiology; Betacoronavirus; COVID-19; Coronavirus Infections; Humans; Pandemics; Pneumonia, Viral; SARS-CoV-2; Asthma; Corticoids – Biologicals; Death; 19; COVID

Abstract :

[en] Given the prominent role of respiratory viruses in asthma exacerbations it has been feared that the SARS-CoV-2 pandemic may result in massive irruption of asthmatic patients in the hospital emergency departments. It seems, however, that asthma is not a particular risk factor for SARS-COV-2 infection nor for death resulting from severe infection. Inhaled corticosteroids (ICS) were found to reduce expression of ACE2 receptor in sputum cells, thereby maybe reducing the risk of lung infection. Only the more severe asthmatic patients treated with oral corticoids or high dose ICS were found to be at risk of death, presumably because of associated comorbidities. Biologicals directed towards IgE or interleukin-5 do not seem to confer an increased risk of severe infection.

Disciplines :

Cardiovascular & respiratory systems

Author, co-author :

Louis, Renaud ; Université de Liège - ULiège > Département des sciences cliniques > Pneumologie - Allergologie

CALMES, Doriane ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de pneumologie - allergologie

Frix, Anne-Noëlle ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de pneumologie - allergologie

Schleich, Florence ; Université de Liège - ULiège > Département des sciences de la motricité > Département des sciences de la motricité

Language :

French

Title :

COVID-19 et asthme.

Alternative titles :

[en] COVID-19 and asthma

Publication date :

2021

Journal title :

Revue Médicale de Liège

ISSN :

0370-629X

eISSN :

2566-1566

Publisher :

Université de Liège. Revue Médicale de Liège, Liège, Belgium

Volume :

Issue :

Pages :

130-132

Peer reviewed :

Peer reviewed

Available on ORBi :

since 22 March 2021

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397 (9 by ULiège)

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203 (4 by ULiège)

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Scopus citations^®

Scopus citations^®
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Bibliography

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