Excised human larynges; Reinke’s edema; Phonotrauma; Contact stress
Abstract :
[en] Objective. To analyze the range of values of the contact pressure between the membranous vocal
folds with Reinke’s edema and to compare it to those observed in the absence of such a lesion.
Methods. Two human larynges were separately tested on the experimental bench, one of them with a bilateral
loose swelling of the vocal folds. Once in a glottal prephonatory configuration, airflow was increased until
achievement of self-sustained oscillations while recording aerodynamic, acoustic, electroglottographic data, and
contact pressure between the folds.
Results. We observed well-documented variations in acoustical parameters, as the decrease of the fundamental
frequency and the increase of the phonation threshold pressure. The results of the study also point to a significant
increase in the amplitude of the contact pressure in presence of the Reinke’s edema, and a lower degree of harmonicity
of the produced sounds.
Conclusion. This is the first report of ex vivo study of a larynx with Reinke’s edema. It highlights the increase in
the contact pressure during phonation, which possibly contributes to sustain the lesion once it appeared.
Disciplines :
Otolaryngology
Author, co-author :
SILVA, FABRICE; LABORATOIRE DE MECANIQUE ET ACOUSTIQUE-CNRS
LEGOU, THIERRY; LABORATOIRE PAROLE ET LANGAGE CNRS
CHAMPSAUR, PIERRE; LABORATOIRE D ANATOMIE FACULTE DE MEDECINE DE MARSEILLE
GIOVANNI, ANTOINE; LABORATORIE PAROLE ET LANGAGE CNRS
Lagier, Aude ; Centre Hospitalier Universitaire de Liège - CHU > Autres Services Médicaux > Service d'ORL, d'audiophonologie et de chir. cervico-faciale
Language :
English
Title :
Contact Pressure Between the Vocal Folds in Reinke’s Edema: Experimental Observations on an Excised Human Larynx
Remacle, M, Degols, JC, Delos, M, Exudative lesions of Reinke's space. An anatomopathological correlation. Acta Otorhinolaryngol Belg 50 (1996), 253–264.
Dikkers, FG, Nikkels, PG, Benign lesions of the vocal folds: histopathology and phonotrauma. Ann Otol Rhinol Laryngol 104:9 Pt 1 (1995), 698–703.
Dikkers, FG, Nikkels, PG, Lamina propria of the mucosa of benign lesions of the vocal folds. Laryngoscope 109 (1999), 1684–1689.
Marcotullio, D, Magliulo, G, Pezone, T, Reinke's edema and risk factors: clinical and histopathologic aspects. Am J Otolaryngol 23 (2002), 81–84.
Verdolini, K, Rosen, CA, Branski, RC, et al. Shifts in biochemical markers associated with wound healing in laryngeal secretions following phonotrauma: a preliminary study. Ann Otol Rhinol Laryngol 112 (2003), 1021–1025.
Titze, IR, Mechanical stress in phonation. J Voice 8 (1994), 99–105.
Verdolini, K, Chan, R, Titze, IR, et al. Correspondence of electroglottographic closed quotient to vocal fold impact stress in excised canine larynges. J Voice 12 (1998), 415–423.
Jiang, JJ, Shah, AG, Hess, MM, et al. Vocal fold impact stress analysis. J Voice 15 (2001), 4–14.
Jiang, JJ, Titze, IR, Measurement of vocal fold intraglottal pressure and impact stress. J Voice 8 (1994), 132–144.
Hess, MM, Verdolini, K, Bierhals, W, et al. Endolaryngeal contact pressures. J Voice 12 (1998), 50–67.
Gunter, HE, Howe, RD, Zeitels, SM, et al. Measurement of vocal fold collision forces during phonation: methods and preliminary data. J Speech Lang Hear Res 48 (2005), 567–576.
Chen, Li-J, Mongeau, L, Verification of two minimally invasive methods for the estimation of the contact pressure in human vocal folds during Phonation. J Acoust Soc Am 130 (2011), 1618–1627.
Verdolini, K, Hess, MM, Titze, IR, et al. Investigation of vocal fold impact stress in human subjects. JVoice 13 (1999), 184–202.
Tan, M, Bryson, PC, Pitts, C, et al. Clinical grading of Reinke's edema. Laryngoscope 127 (2017), 2310–2313.
Alipour, F, Finnegan, EM, Jaiswal, S, Phonatory characteristics of the excised human larynx in comparison to other species. J Voice 27 (2013), 441–447.
Lagier, A, Guenoun, D, Legou, T, et al. Control of the glottal configuration in ex vivo human models: quantitative anatomy for clinical and experimental practices. Surg Radiol Anat 39 (2017), 257–262.
Legou, T, Lagier, A, Silva, F, et al. Test bench for human excised larynx studies. Manfredi, C, (eds.) Models and Analysis of Vocal Emissions for Biomedical Applications: 9th International Workshop, 2015, Firenze University Press, Firenze.
Bergeot, B, Almeida, A, Gazengel, B, et al. Response of an artificially blown clarinet to different blowing pressure profiles. J Acoust Soc Am 135 (2014), 479–490.
de Cheveigné, A, Kawahara, H, YIN, a fundamental frequency estimator for speech and music. J Acoust Soc Am 111 (2002), 1917–1930.
Kasuya, H, Ogawa, S, Kikuchi, Y, An adaptive comb filtering method as applied to acoustic analyses of pathological voice. IEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP ’86), 1986, IEEE, 669–672.
Hirano, M, Tanaka, S, Fujita, M, et al. Fundamental frequency and sound pressure level of phonation in pathological states. J Voice 5:2 (1991), 120–127.
Matar, N, Portes, C, Lancia, L, et al. Voice quality and gender stereotypes: a study of lebanese women with Reinke's edema. J Speech Lang Hear Res 59:6 (2016), S1608–S1617.
Garcia, M, Herbst, CT, Excised larynx experimentation: history, current developments, and prospects for bioacoustic research. Anthropol Sci 126:1 (2018), 9–17.