Hypertension arterielle pulmonaire et bronchopathie chronique obstructive

[en] In this paper we review the current knowledge on pulmonary hypertension (PH) occurring in COPD. PH is defined as a mean pulmonary arterial pressure at rest greater than 20 mmHg measured by right heart catheterisation. PH is usually present during exercise before appearing at rest. PH in COPD increases the risk of hospitalisation and darkens the disease prognosis. Chronic hypoxemia is the major contributor to PH, but remodelling of arterial wall and mechanical factors such as hyperinflation also play a role. Transthoracic echocardiography is the most useful non invasive investigation, but right heart catheterisation is necessary to ascertain the diagnosis. Long term 02 supplementation is the basis of the treatment while vasodilatators may worsen hypoxemia.

Disciplines :

General & internal medicine

Author, co-author :

Naldi, Marco ; Centre Hospitalier Universitaire de Liège - CHU > Pneumologie-Allergologie

D'Orio, Vincenzo ; Université de Liège - ULiège > Département des sciences cliniques > Médecine d'urgence - bioch. et phys. hum. normales et path.

Louis, Renaud ; Université de Liège - ULiège > Département des sciences cliniques > Pneumologie - Allergologie

Language :

French

Title :

Hypertension arterielle pulmonaire et bronchopathie chronique obstructive

Alternative titles :

[en] Pulmonary Arterial Hypertension Due to Copd

Publication date :

2006

Journal title :

Revue Médicale de Liège

ISSN :

0370-629X

eISSN :

2566-1566

Publisher :

Université de Liège. Revue Médicale de Liège, Liège, Belgium

Volume :

Issue :

7-8, Jul-Aug

Pages :

563-71

Peer reviewed :

Peer reviewed

Available on ORBi :

since 14 October 2009

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377 (4 by ULiège)

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